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Questions and Answers

What are the main characteristics of normal microbial flora in the mouth?

Millions of bacteria present in 1 mL of saliva.

What is the bacterial concentration in the large intestine?

100 billion bacteria per gram of feces, making up 40% of fecal mass.

Which of these factors can make normal flora pathogenic? (Select all that apply)

  • Balanced diet
  • Host is immunocompromised (correct)
  • Healthy immune system
  • Chronic antibiotic use (correct)
  • What are the advantages of normal residential flora? (Select all that apply)

    <p>Production of vitamin K</p> Signup and view all the answers

    Which of the following are predisposing factors for diarrheal diseases? (Select all that apply)

    <p>Extremes of age</p> Signup and view all the answers

    The term _______________ refers to inflammation of the intestines with severe abdominal cramps and frequent low-volume stools.

    <p>Dysentery</p> Signup and view all the answers

    What is an enterotoxin?

    <p>An exotoxin with enteric activity affecting the intestinal tract.</p> Signup and view all the answers

    The presence of gut flora does not contribute to the immune system.

    <p>False</p> Signup and view all the answers

    What characterizes bacillary dysentery?

    <p>Caused by bacterial infection with invasion of host cells and/or production of exotoxins.</p> Signup and view all the answers

    Which of the following can be considered a mechanical barrier in gastrointestinal defenses?

    <p>Tight junctions between epithelial cells</p> Signup and view all the answers

    Study Notes

    Oral Microbial Flora Characteristics

    • Oral flora is diverse and includes numerous types of bacteria, including aerobic and anaerobic species.
    • The composition of oral flora is influenced by factors such as age, diet, and oral hygiene practices.
    • Some bacteria in oral flora contribute to dental plaque formation, which can lead to tooth decay and gum disease.
    • Key fact: Oral flora plays a crucial role in maintaining oral health, and imbalances in its composition can compromise oral health.

    Bacterial Concentration in the Large Intestine

    • Key fact: The large intestine harbors a high concentration of bacteria, estimated to be around 10^11 to 10^12 bacteria per gram of feces.

    Factors that Can Make Normal Flora Pathogenic

    • Compromised host defenses: Weakened immune systems can allow opportunistic pathogens to proliferate.
    • Introduction of new strains: Changes in the normal flora, such as antibiotic use, can create opportunities for new, potentially pathogenic strains to establish themselves.
    • Changes in the host environment: Factors like pH imbalances or changes in the composition of the gut microbiota can favor the growth of pathogenic bacteria.

    Advantages of Normal Residential Flora

    • Competition with pathogens: Normal flora occupies niches and competes with pathogens for resources, inhibiting their growth.
    • Production of antimicrobial substances: Certain bacteria in normal flora produce substances that inhibit the growth of other bacteria, including pathogens.
    • Stimulation of the immune system: The presence of diverse bacteria in normal flora helps to train and strengthen the immune system.

    Predisposing Factors for Diarrheal Diseases

    • Infections: Viral, bacterial, and parasitic infections can lead to diarrhea by causing intestinal inflammation, damage, or fluid imbalance.
    • Food poisoning: Ingestion of contaminated food containing toxins or bacteria can trigger diarrheal symptoms.
    • Malabsorption: Disorders that impair nutrient absorption in the intestines can lead to diarrhea, often accompanied by other symptoms.
    • Certain medications: Some medications, such as antibiotics, can disrupt the balance of gut bacteria and contribute to diarrhea.

    Inflammation of the Intestines

    • Key fact: The term enteritis refers to the inflammation of the intestines, characterized by severe abdominal cramps and frequent low-volume stools.

    Enterotoxin

    • Key fact: An enterotoxin is a type of toxin produced by certain bacteria that specifically affects the intestines, causing gastrointestinal distress.

    Gut Flora and Immune System

    • Key fact: The presence of gut flora plays a significant role in the development and function of the immune system, and its absence can lead to a weakened immune response.

    Bacillary Dysentery

    • Key fact: Bacillary dysentery is characterized by intestinal inflammation and bloody diarrhea caused by bacteria such as Shigella.

    Mechanical Barrier in Gastrointestinal Defenses

    • Key fact: The lining of the gastrointestinal tract, including the mucous membrane and tight junctions between cells, acts as a physical barrier, preventing the entry of pathogens into the bloodstream.

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