Rabies
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Questions and Answers

What type of genetic material does the rabies virus possess?

  • dsDNA
  • ssRNA (correct)
  • dsRNA
  • ssDNA
  • Which of the following is NOT a common source of rabies in the US?

  • Skunks
  • Cats (correct)
  • Bats
  • Coyotes
  • How does the rabies virus progress after entering through a bite?

  • Attacks the immune system first
  • Immediately attacks the brain
  • Spreads through the bloodstream instantly
  • Multiplies at the bite site before entering nerves (correct)
  • What is one of the primary characteristics of rabies progression?

    <p>Very slow progression with a long incubation period</p> Signup and view all the answers

    What neurological symptom occurs first in untreated rabies progression?

    <p>Fever</p> Signup and view all the answers

    What is the primary method of confirming rabies post-mortem?

    <p>Finding Negri bodies in the brain</p> Signup and view all the answers

    What preventive measure has the government implemented to control rabies among wild animals?

    <p>Distribution of food containing rabies vaccine</p> Signup and view all the answers

    What is a common misconception regarding rabies vaccination after exposure?

    <p>There is no time for vaccination after exposure</p> Signup and view all the answers

    Who is at risk of rabies infection?

    <p>All mammals</p> Signup and view all the answers

    What does rabies exemplify in its nature as an infection?

    <p>Zoonosis</p> Signup and view all the answers

    Match the following mammals with their rabies risk status:

    <p>Skunks = Common rabies carriers in the US Bats = Most common source of rabies in the US Dogs = Primary rabies risk in countries without vaccination Cats = Former common source of rabies in the US</p> Signup and view all the answers

    Match the stages of rabies progression with their symptoms:

    <p>Initial stage = Fever, headache, and fatigue Middle stage = Agitation and disorientation Severe stage = Paralysis and coma Final stage = Death</p> Signup and view all the answers

    Match the following rabies characteristics with their descriptions:

    <p>Zoonosis = Infection normally found in animals transmissible to humans ssRNA genome = Type of genetic material in rabies virus Helical capsid = Shape of the rabies virus structure Bullet-shaped envelope = Distinctive feature of the rabies virus</p> Signup and view all the answers

    Match the rabies facts with their implications:

    <p>Vaccination post-exposure = Possible due to slow progression of rabies Rabies diagnosis = Often confirmed at autopsy Negri bodies = Sites of virus replication in the brain Wild animal vaccination program = Government initiative for prevention</p> Signup and view all the answers

    Match the following rabies virus transmission scenarios:

    <p>Domesticated animal bites = Less common source in the US today Wild animal bites = Primary source of rabies cases now Dog bites = Major risk in countries with poor vaccination Coyote encounters = Potential rabies exposure in the wild</p> Signup and view all the answers

    Match the symptoms of rabies infection with their stages:

    <p>Hydrophobia = Middle stage symptom Fatigue = Initial stage symptom Coma = Severe stage symptom Disorientation = Middle stage symptom</p> Signup and view all the answers

    Match health responses to rabies scenarios:

    <p>Bite prevention = Avoiding wild animal encounters Post-exposure treatment = Vaccination after a suspicious bite Veterinary vaccination campaigns = Reducing domestic animal rabies risk Wildlife rabies vaccination = Protecting both animals and humans</p> Signup and view all the answers

    Match the following rabies symptoms with their order of progression:

    <p>Fever = First symptom Agitation = Second symptom Hydrophobia = Third symptom Paralysis = Final symptom</p> Signup and view all the answers

    Match the following measures with their rabies control purpose:

    <p>Veterinary vaccinations = Increase domestic animal immunity Wild animal vaccination programs = Reduce wild animal reservoirs Public health awareness = Encourage prompt medical responses Post-exposure prophylaxis = Prevent infection after bites</p> Signup and view all the answers

    Match the following rabies virus characteristics with their specifics:

    <p>Reservoir = Wild mammals in the US Transmission route = Through animal bites or scratches Symptom onset = Can take weeks to months Fatality rate when untreated = 100%</p> Signup and view all the answers

    Study Notes

    Rabies Virus

    • Rabies is a zoonotic disease caused by a virus belonging to the rhabdovirus group.
    • The virus has a single-stranded RNA genome (ssRNA), a helical capsid, and a distinctive bullet-shaped envelope.
    • The virus is found in the saliva of infected animals.
    • All mammals are susceptible to rabies infection.
    • In the US, the main reservoir for rabies is wild mammals.

    Rabies Transmission

    • The most common way for humans to contract rabies is through a bite from an infected animal.
    • Other ways of transmission include scratches, licking, and contact with contaminated saliva.
    • In the US, bats are the most common source of rabies.
    • Other common sources include skunks, coyotes, and raccoons.
    • In countries with weak veterinary vaccination programs, dog bites are a major source of rabies.

    Rabies Progression

    • After entering the body through a bite, the virus multiplies at the bite site for a week.
    • The virus then travels through nerves to the spinal cord, brain, and salivary glands.
    • This progression can take weeks or months, allowing time for post-exposure treatment.

    Rabies Symptoms

    • Initial symptoms include fever, headache, and fatigue.
    • As the disease progresses, symptoms can include agitation, disorientation, hydrophobia, paralysis, coma, and death.
    • Untreated rabies is 100% fatal.
    • Diagnosis often involves finding Negri bodies in the brain during autopsy.

    Rabies Prevention and Treatment

    • Vaccination is the most effective way to prevent rabies.
    • Post-exposure vaccination is effective if administered promptly after a bite or scratch.
    • The government has initiated a wild animal rabies vaccination program using food baits containing the vaccine.
    • The goal is to protect both wild animals and humans from rabies.

    Rabies Virus

    • Part of the rhabdovirus group
    • Single-stranded RNA genome (ssRNA)
    • Helical capsid
    • Distinctive bullet-shaped envelope

    Rabies Transmission

    • Transmissible to all mammals
    • Reservoir in wild mammals
    • Primarily transmitted through bites
    • US: Bats, skunks, coyotes, raccoons
    • Other countries: Dogs

    Zoonosis

    • Infection normally found in animals
    • Transmissible to humans

    Rabies Progression

    • Slow progression (weeks to months)
    • Virus multiplies at bite site for a week
    • Enters nerves and moves to spinal cord, brain, and salivary glands
    • Time for post-exposure vaccination

    Symptoms

    • Fever, headache, fatigue
    • Agitation, disorientation, hydrophobia
    • Paralysis, coma, death

    Treatment

    • Post-exposure vaccination available
    • Vaccination effective if administered before symptoms develop

    Mortality

    • 100% fatal if untreated
    • Diagnosis often confirmed post-mortem by finding Negri bodies in the brain

    Rabies Prevention

    • US government vaccination programs for wild animals
    • Vaccine-laced food left for wild animals to consume

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    Description

    This quiz covers essential information about the rabies virus, including its characteristics, transmission methods, and progression in hosts. Test your knowledge on how rabies affects mammals, the common sources of infection, and the disease’s effects on humans. Perfect for biology students and anyone interested in infectious diseases.

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