Quinoline Synthesis in Organic Chemistry

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Questions and Answers

In Combes synthesis, what is used to give β-aminoenone?

  • Aldehydes
  • β- Arylethylamines
  • Substituted α,β-unsaturated
  • 1,3-dicarbonyl compound with an arylamine (correct)

Which type of medication is used to treat and prevent malaria?

  • Acrolein
  • 1,3-dicarbonyl compound
  • Sub aniline
  • Primaquine & chloroquine (correct)

Which group must be present p- to the point of cyclization in the Pictet-Spengler synthesis?

  • +I group
  • -I group
  • +M group (correct)
  • -M group

What is the evidence for Michael addition according to Dr/HZM - 3 Sigma Organic Chemistry - III 2024 Extra?

<p>Substituted α,β-unsaturated (A)</p> Signup and view all the answers

What may occur if starting with acrolein due to toxicity in Quinoline synthesis?

<p>Self condensation may occur in acidic medium (C)</p> Signup and view all the answers

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