Quinidine: Adverse Effects, Drug Interactions, and Unique Features

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Match the following with their mechanism of action:

Organic Nitrates = Works directly on smooth muscle to promote dilation of veins Quinidine = Both tachy and brady mechanisms Nitroglycerin = Promotes dilation of veins Anti-dysrhythmias = Changes in the EKG

Match the following with their therapeutic uses:

Quinidine = First line for African-American population BP, HF & hypertensive crisis Organic Nitrates = Used for angina pectoris Nitroglycerin = Works for angina pectoris Anti-dysrhythmias = Used for dysrhythmias

Match the following with their adverse effects:

Quinidine = Anorexia*--an early sign of toxicity Organic Nitrates = Headache Nitroglycerin = Orthostatic hypotension and reflex tachycardia Anti-dysrhythmias = CNS and GI adverse effects

Match the following with specific drugs:

Quinidine = Specific Drugs Many drug interactions Organic Nitrates = 548 Nitroglycerin = Lots of different routes and durations Anti-dysrhythmias = Several categories Signup and view all the answers

Match the following with potential drug interactions:

Quinidine = No grapefruit juice Organic Nitrates = All hypotensive drugs especially beta blockers Nitroglycerin = Many drug interactions Anti-dysrhythmias = Many drug interactions Signup and view all the answers

Match the following drugs with their primary therapeutic uses:

Captopril = High BP, HF, Nephropathy Enalapril = High BP, HF Losartan = High BP, Stroke prevention, Diabetic nephropathy Olmesartan = High BP Signup and view all the answers

Match the following drug classes with their mechanism of action:

Direct Renin Inhibitors (e.g., Aliskirin) = Inhibits conversion of angiotensinogen into angiotensin I Aldosterone Antagonists (e.g., Eplerenone) = Selective aldosterone receptor blocker Signup and view all the answers

Match the following adverse effects with the associated drugs:

Hyperkalemia = ACE Inhibitors Angioedema = ACE Inhibitors Cough = Direct Renin Inhibitors (Aliskirin) Increased capillary permeability = ACE Inhibitors Signup and view all the answers

Match the following drugs with their specific usage:

Valsartan = High BP, HF, MI Lisinopril = High BP, HF, MI Olmesartan = High BP only Captopril = High BP, HF, Nephropathy Signup and view all the answers

Match the following drug interactions with the associated medications:

Drugs that increase K levels = ACE Inhibitors Lithium = Drugs that increase K levels NSAIDs = Drugs that increase K levels Diuretics; Other antihypertensive drugs = ACE Inhibitors Signup and view all the answers

Match the following cardiovascular system medication with their mechanism of action:

Angiotensin Converting Enzyme Inhibitor = Reduces levels of angiotensin II and dilates blood vessels Angiotensin Receptor Blockers (ARBs) = Blocks access to receptors in blood vessels and increases levels of bradykinins Signup and view all the answers

Match the following cardiovascular system medication with their therapeutic uses:

Angiotensin Converting Enzyme Inhibitor = Uses for HF & MI and Nephropathy Angiotensin Receptor Blockers (ARBs) = Uses for HF & MI and Diabetic nephropathy Signup and view all the answers

Match the following cardiovascular system medication with their adverse effects:

Angiotensin Converting Enzyme Inhibitor = Cough, dizziness, diarrhea Angiotensin Receptor Blockers (ARBs) = Dizziness, muscle cramps or weakness, heartburn Signup and view all the answers

Match the following cardiovascular system medication with their specific drugs:

Angiotensin Converting Enzyme Inhibitor = Ends with 'ipril' Angiotensin Receptor Blockers (ARBs) = Ends with 'artan' Signup and view all the answers

Match the following cardiovascular system medication with potential drug interactions:

Angiotensin Converting Enzyme Inhibitor = Need to lower initial dose or stop diuretics 2-3 days Angiotensin Receptor Blockers (ARBs) = Especially if on diuretic, so need to lower initial dose or stop diuretics 2-3 days Signup and view all the answers

Match the following cardiovascular medication category with its primary mechanism of action:

Calcium Channel Blockers (CCB) = Prevents calcium from entering cells, especially at heart & blood vessels Cardiac Glycosides = Inotropic—increases force of contraction, slows conduction and increases refractory period Vasodilators = Wide variety of mechanisms including absorption variable; excretion slow Organic nitrates = Relaxes blood vessels, mainly veins, to reduce workload on the heart Signup and view all the answers

Match the following cardiovascular medication with its major therapeutic use:

Amlodipine = Hypertension Hydralazine = Hypertensive emergency in ER Verapamil = Dysrhythmias Minoxidil = Severe hypertension Signup and view all the answers

Match the following adverse effects with the corresponding medication category:

Headaches, drowsiness, flushing, fatigue, dizziness, edema = Calcium Channel Blockers (CCB) Constipation/dysrhythmia = Calcium Channel Blockers (CCB) Anorexia, nausea/vomiting, diplopia = Vasodilators Postural hypotension and reflex tachycardia = Calcium Channel Blockers (CCB) Signup and view all the answers

Match the following cardiovascular medication with its specific use:

Nifedipine = Angina pectoris Nitroprusside = Hypertensive emergency in ER Digoxin = Inotropic support in heart failure Diltiazem = Dysrhythmias Signup and view all the answers

Match the following drug classes with their primary mechanism of action:

Class I - Sodium channel blockers = Blocks sodium channels in cardiac tissues Class II - Beta adrenergic blockers = Blocks beta adrenergic receptors leading to decreased heart rate and contractility Class III - Potassium channel block = Blocks potassium channels in cardiac tissues Class IV - Calcium channel block = Blocks calcium channels in cardiac tissues Signup and view all the answers