Quinidine Adverse Effects and Drug Interactions Quiz
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Questions and Answers

Which of the following is a common side effect associated with the use of ACE inhibitors like captopril, enalapril, and lisinopril?

  • Hyperglycemia
  • Angioedema (correct)
  • Drowsiness
  • Constipation

Which of the following is the primary mechanism of action of the direct renin inhibitor aliskiren?

  • Directly stimulating the release of renin from the kidneys
  • Blocking the action of angiotensin II at the AT1 receptor
  • Inhibiting the conversion of angiotensinogen to angiotensin I (correct)
  • Increasing the production of aldosterone

Which of the following is a key difference between the aldosterone antagonist eplerenone and the diuretic spironolactone?

  • Eplerenone has a longer half-life
  • Eplerenone is associated with a higher risk of hyperkalemia
  • Eplerenone is less selective for the aldosterone receptor
  • Eplerenone has fewer side effects than spironolactone (correct)

Which of the following conditions is losartan specifically indicated for, in addition to hypertension?

<p>Diabetic nephropathy (B)</p> Signup and view all the answers

What is the primary difference between the angiotensin II receptor blockers (ARBs) like losartan, olmesartan, and valsartan?

<p>There are no significant differences between these ARBs in their indications or mechanisms of action (C)</p> Signup and view all the answers

Which of the following is a common drug interaction associated with the use of ACE inhibitors?

<p>Increased risk of hyperkalemia with potassium-sparing diuretics (B)</p> Signup and view all the answers

Which of the following is a calcium channel blocker (CCB)?

<p>Amlodipine (B)</p> Signup and view all the answers

What is the primary therapeutic use of verapamil?

<p>Dysrhythmias (D)</p> Signup and view all the answers

Which of the following drugs is NOT a calcium channel blocker?

<p>Digoxin (D)</p> Signup and view all the answers

What is a potential adverse effect of nifedipine?

<p>Postural hypotension and reflex tachycardia (B)</p> Signup and view all the answers

Which drug is used in hypertensive emergencies due to its fast-acting nature?

<p>Nitroprusside (C)</p> Signup and view all the answers

Which of the following statements about digoxin is correct?

<p>It is considered a second-line treatment option (B)</p> Signup and view all the answers

Which of the following is a specific adverse effect associated with the use of quinidine?

<p>Lupus-like syndrome (B)</p> Signup and view all the answers

What is the relationship between the effective dose and toxic dose of quinidine?

<p>The effective dose is close to the toxic dose. (D)</p> Signup and view all the answers

Which of the following statements is true about the use of organic nitrates?

<p>They work directly on smooth muscle to promote dilation of veins, thereby decreasing oxygen demand. (D)</p> Signup and view all the answers

What is the primary mechanism by which organic nitrates are used to treat angina pectoris?

<p>They decrease oxygen demand in the heart. (C)</p> Signup and view all the answers

Which of the following is a specific drug interaction associated with organic nitrates?

<p>Interactions with antihypertensive drugs. (B)</p> Signup and view all the answers

What is a key factor that can affect the stability and potency of organic nitrates?

<p>All of the above. (D)</p> Signup and view all the answers

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