Quinidine Adverse Effects and Drug Interactions Quiz
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Questions and Answers

Which of the following is NOT a common adverse effect associated with quinidine?

  • Gastrointestinal effects
  • Central nervous system effects
  • Hepatotoxicity (correct)
  • Increased risk of dysrhythmias

    • What is the primary mechanism of action for organic nitrates, such as nitroglycerin?

  • Direct vasodilation of veins to decrease preload (correct)
  • Inhibition of angiotensin-converting enzyme
  • Inhibition of platelet aggregation
  • Stimulation of adrenergic receptors to increase heart rate

    • Which of the following is a unique adverse effect associated with quinidine?

  • Lupus-like syndrome (correct)
  • Orthostatic hypotension
  • Anorexia
  • Headache

    • What is a significant drug interaction associated with quinidine?

    <p>Increased metabolism with grapefruit juice</p> Signup and view all the answers

    Which population is quinidine considered a first-line treatment for?

    <p>African American patients</p> Signup and view all the answers

    What is the primary mechanism of action of calcium channel blockers (CCBs)?

    <p>Prevents calcium from entering cells, especially in the heart and blood vessels</p> Signup and view all the answers

    Which of the following is a common therapeutic use of calcium channel blockers?

    <p>Hypertension and angina pectoris</p> Signup and view all the answers

    Which of the following is a common adverse effect associated with the use of calcium channel blockers?

    <p>Constipation and dysrhythmias</p> Signup and view all the answers

    Which specific calcium channel blocker is known to primarily affect the heart rather than the vasculature?

    <p>Verapamil</p> Signup and view all the answers

    Which class of drugs is considered a second-line option for the treatment of hypertension compared to calcium channel blockers?

    <p>Cardiac glycosides</p> Signup and view all the answers

    Which of the following best describes the mechanism of action of ACE inhibitors?

    <p>They reduce levels of angiotensin II, dilating blood vessels</p> Signup and view all the answers

    Which class of drugs is known for causing a dry, irritating cough as a side effect?

    <p>Angiotensin converting enzyme inhibitors (ACE inhibitors)</p> Signup and view all the answers

    Which of the following therapeutic uses is NOT associated with ACE inhibitors or ARBs?

    <p>Treatment of asthma</p> Signup and view all the answers

    Which of the following is a potential drug interaction with ACE inhibitors?

    <p>Increased risk of first-dose hypotension when taken with diuretics</p> Signup and view all the answers

    Which of the following statements regarding ARBs is correct?

    <p>They are less likely to cause cough and angioedema compared to ACE inhibitors</p> Signup and view all the answers

    Which of the following is the primary mechanism of action for ACE inhibitors?

    <p>Inhibition of the conversion of angiotensin I to angiotensin II</p> Signup and view all the answers

    Which of the following is a common adverse effect associated with ACE inhibitors?

    <p>Hyperkalemia</p> Signup and view all the answers

    Which of the following ACE inhibitors is specifically mentioned for use in diabetic nephropathy?

    <p>Losartan</p> Signup and view all the answers

    Which of the following drug classes has a lower risk of cough and angioedema compared to ACE inhibitors?

    <p>Direct renin inhibitors</p> Signup and view all the answers

    Which of the following statements about aldosterone antagonists is correct?

    <p>Eplerenone is used for treatment of hypertension and heart failure</p> Signup and view all the answers

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