Intro to (PFTs)

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Questions and Answers

Indications for spirometry include detecting the presence or absence of lung ______ suggested by history or physical signs and symptoms.

dysfunction

A circumstance that could affect the reliability of spirometry measurements is ______ of unknown origin.

hemoptysis

A potential hazard or complication of spirometry is ______ coughing.

paroxysmal

Every day before testing, volume verification uses a calibrated known-volume ______ with a volume of at least 3 L to ascertain that the spirometer reads a known volume accurately.

<p>syringe</p> Signup and view all the answers

If possible, computer software for measurement and computer calculations should be checked against ______ calculations.

<p>manual</p> Signup and view all the answers

Each laboratory or testing site should develop, establish, and implement quality ______ indicators for equipment calibration and maintenance and patient preparation.

<p>assurance</p> Signup and view all the answers

The following should be evaluated during the performance of spirometric measurements to ascertain the validity of the results: Acceptability of maneuver and ______ of PVC and FEV₁.

<p>reproducibility</p> Signup and view all the answers

Assess response to therapeutic interventions; transplantation, radiation, chemotherapy, ______.

<p>lobectomy</p> Signup and view all the answers

With respect to whole-body plethysmography, factors such as ______, upper body paralysis, obtrusive body casts, or other conditions that immobilize or prevent the patient from fitting into or gaining access to the 'body box' are a concern.

<p>claustrophobia</p> Signup and view all the answers

One hazard and complication of measuring lung volumes is depressed ______ drive in susceptible subjects as a consequence of breathing 100% $O_2$ during the nitrogen washout.

<p>ventilatory</p> Signup and view all the answers

Outcome and test quality are determined by ascertaining that the desired information has been generated for the specific indication and that ______ and reproducibility have been ensured.

<p>validity</p> Signup and view all the answers

Equipment calibration and quality control measures specific to measuring lung volumes should be applied and ______.

<p>documented</p> Signup and view all the answers

[Blank] lung disease is a category of pulmonary disease.

<p>obstructive</p> Signup and view all the answers

Asthma is an example of an ______ lung disorder.

<p>obstructive</p> Signup and view all the answers

[Blank] volume, inspiratory reserve volume, expiratory reserve volume, and residual volume are the four lung volumes.

<p>tidal</p> Signup and view all the answers

Vital capacity, inspiratory capacity, functional residual capacity, and total lung ______ are the four lung capacities.

<p>capacity</p> Signup and view all the answers

Height, age, gender, and ______ are how we get the 'predicted' values.

<p>race</p> Signup and view all the answers

The Ideal Body Weight for a male is: 106 + (6 x Ht Inches) / 2.2 = Ideal Body weight in ______.

<p>kg</p> Signup and view all the answers

[Blank] tests measure ability of lungs to move large volumes of air quickly through airways.

<p>spirometry</p> Signup and view all the answers

main types of pulmonary function ______.

<p>Vol flo Diffusion</p> Signup and view all the answers

[Blank] includes tests such as a 6 & 12 minute walk.

<p>other</p> Signup and view all the answers

FVC, SVC, MVV, RV/FRC, DLCO, and post FVC are all parts of a ______ PFT order.

<p>full</p> Signup and view all the answers

[Blank] volume, inspiratory reserve volume, expiratory reserve volume, and residual volume are lung volumes.

<p>tidal</p> Signup and view all the answers

Identify & quantify changes in pulmonary function due to ______ is one of the purposes of PFT.

<p>disease</p> Signup and view all the answers

[Blank] is an example of a contraindication to pulmonary function testing.

<p>pneumothorax</p> Signup and view all the answers

Obstructive and ______ are the two main categories of pulmonary disease.

<p>restrictive</p> Signup and view all the answers

Spirometers and pneumotachometers are examples of PFT ______.

<p>equipment</p> Signup and view all the answers

Accuracy and precision are Elements of Quality ______.

<p>Assurance</p> Signup and view all the answers

Restrictive disease will not increase lung ______.

<p>volumes</p> Signup and view all the answers

[Blank] is used to measure airway mechanics.

<p>spirometry</p> Signup and view all the answers

The ______ vital capacity measures the most common test.

<p>forced</p> Signup and view all the answers

[Blank] is the highest point on flow-volume graph.

<p>PEFR</p> Signup and view all the answers

It's important to know that the FEV1/______ should be at least 70%.

<p>FVC</p> Signup and view all the answers

Normal MVV for males is 160 to 180 L/min & slightly lower in ______.

<p>females</p> Signup and view all the answers

Reversibility is defined as 12% & 200 ml from predose in FEV₁ &/or ______.

<p>FVC</p> Signup and view all the answers

Helium dilution is a technique used for measuring ______ volume.

<p>residual</p> Signup and view all the answers

Exercise is not a factor that can ______ the diffusing capacity of the lungs.

<p>decrease</p> Signup and view all the answers

Quality Assurance of Spirometry uses a 3.0 L syringe used for accuracy & precision of volume or ______.

<p>flow</p> Signup and view all the answers

One of three ways to perform measurements for residual volumes (RV) is ______.

<p>body box</p> Signup and view all the answers

FEV1/FVC is less than 70%, this would indicate; obstructive ______.

<p>disease</p> Signup and view all the answers

The functional ______ capacity consists of expiratory reserve volume and residual volume.

<p>residual</p> Signup and view all the answers

The indications for spirometry include detecting the presence or absence of lung ______.

<p>dysfunction</p> Signup and view all the answers

A circumstance that could affect the reliability of spirometry is performing the procedure on someone with ______ of an unknown origin.

<p>hemoptysis</p> Signup and view all the answers

Before each test, a calibrated known-volume ______ should be used to ascertain that the spirometer reads a known volume accurately.

<p>syringe</p> Signup and view all the answers

A volume-displacement spirometer must be evaluated for ______ daily.

<p>leaks</p> Signup and view all the answers

Spirometry helps to differentiate between obstructive and ______ disease patterns.

<p>restrictive</p> Signup and view all the answers

Quantifying the amount of gas ______ is achieved by through comparing results of different lung function techniques.

<p>trapping</p> Signup and view all the answers

The measurement and computer calculations of spirometry software should be regularly checked against ______ calculations for accuracy.

<p>manual</p> Signup and view all the answers

The assessment of outcome and test quality is the outcome and test quality are determined by ascertaining that the desired information has been generated for the specific ______.

<p>indication</p> Signup and view all the answers

The measurement of lung volumes require equipment calibration and ______ control measures specific.

<p>quality</p> Signup and view all the answers

A primary problem in ______ disease is a decrease in either lung compliance or lung volumes, or both.

<p>restrictive</p> Signup and view all the answers

Lung volumes and capacities are measured using volume measuring devices, also known as ______.

<p>spirometers</p> Signup and view all the answers

Lung volumes and capacities can be measured using flow measuring devices also known as ______.

<p>pneumotachometers</p> Signup and view all the answers

Elements of quality assurance contains the ______ and precision of measuring instruments.

<p>accuracy</p> Signup and view all the answers

During the maximal voluntary ventilation (MVV) test, the patient is asked to breathe deep and fast for ______ seconds.

<p>12</p> Signup and view all the answers

A 3.0 L ______ is used for assurance of accuracy and precision of volume or flow.

<p>syringe</p> Signup and view all the answers

Flashcards

Indications for Spirometry

Detect lung dysfunction, quantify severity, assess changes over time, evaluate exposure effects, and assess surgical risks.

Contraindications for Spirometry

Hemoptysis, pneumothorax, unstable cardiovascular status, aneurysms, recent eye surgery, or acute illness.

Hazards of Spirometry

Pneumothorax, coughing, increased intracranial pressure, infection, syncope, desaturation, chest pain, and bronchospasm.

Volume Verification

Verifying volume accuracy using a calibrated syringe.

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Monitoring During Spirometry

Acceptability of maneuver, reproducibility of FVC and FEV1, patient effort, equipment function, and test quality.

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Indications for Lung Volume Determination

Diagnose restrictive disease patterns, differentiate between obstructive and restrictive diseases, and evaluate pulmonary disability.

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Contraindications for Lung Volume Determination

Hemoptysis, pneumothorax, unstable cardiovascular status, and thoracic aneurysms.

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Hazards of Lung Volume Determination

Nosocomial infection, hypoxemia, and depressed ventilatory drive in CO2 retainers.

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Assessing Lung Volume Test Quality

Valid equipment, patient understanding and effort, and all quality control measures applied.

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Four Lung Volumes

Tidal Volume (VT), Inspiratory Reserve Volume (IRV), Expiratory Reserve Volume (ERV), and Residual Volume (RV).

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Four Lung Capacities

Vital Capacity (VC), Inspiratory Capacity (IC), Functional Residual Capacity (FRC), and Total Lung Capacity (TLC).

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Factors for Predicted Values

Height, age, gender, and race.

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Ideal Body Weight(Male)

106 + (6 x inches over 5ft) / 2.2

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Ideal Body Weight(Female)

105 + (5 x inches over 5ft) / 2.2

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Main Types of PFTs

Spirometry (volume),Flows, and Diffusion.

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Other Types of PFTs

6/12 minute walk, MIP/MEP, PF, ABG's and other.

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Full PFT Includes

FVC, SVC, MVV, RV/FRC, DLCO, Post FVC.

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Tidal Volume (TV)

Volume of air entering/leaving lungs during a single breath.

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Inspiratory Reserve Volume (IRV)

Extra air maximally inhaled over typical breath.

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Expiratory Reserve Volume (ERV)

Extra air actively exhaled by maximal contraction.

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Residual Volume (RV)

Minimum air remaining after maximal exhalation.

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Purposes of PFTs

Identify/quantify changes, evaluate therapy, surveillance, assess post-op risk, determine disability.

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Not Contraindication for PFT

Hypertension.

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Categories of Pulmonary Disease

Obstructive and Restrictive.

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Physiologic Patterns of Disease

Obstructive= Increased airways resistance, Restrictive= Decrease in lung volumes/compliance.

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General Types of PFT Measuring Devices

Measure volume & Measure flow.

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Elements of Quality Assurance

instruments, Respiratory Therapist (RT), and standard.

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Not a Pathophysiologic Patterns of Pulmonary Disease

Restrictive disease will increase lung volumes.

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Components of Measurement

Spirometry, measuring lung volumes and capacities and Measuring diffusion capacity of lung.

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What Spirometry Tests?

Forced vital capacity (FVC) and Forced expiratory volume in 1 second (FEV1).

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Value of Spirometry Test

Assess ability of lungs to move large air volumes quickly.

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Forced Vital Capacity (FVC)

The most common test (VC).

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What is FEV1?

Volume of gas exhaled in first 1-second of FVC maneuver.

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FEV1/FVC is calculated

Dividing largest FEV1 by largest FVC.

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Maximal Voluntary Ventilation (MVV)

Breathe deep & fast for 12 seconds.

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  1. 0 L Syringe

Accuracy of volume or flow.

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What does FEV₁ indicate?

Reduced with both obstructive & restrictive lung disease.

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If Obstruction is Present

Reversibility must be evaluated.

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FEV1/FVC < 70%

Obstructive disease.

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What Lung Capacities?

total lung capacity, Inspiratory capacity, Functional residual capacity and Vital capacity.

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Functional Residual Capacity Volume

Expiratory reserve volume and residual volume.

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Techniques for Measuring Residual Volume (RV)

Helium dilution and Nitrogen washout.

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Decreases Diffusing Capacity

Pulmonary emphysema.

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Study Notes

Introduction to PFTs

  • Pulmonary Function Tests (PFTs) help assess lung function and diagnose respiratory conditions

Types of Pulmonary Function Tests

  • Three main categories: Volume, Flow, Diffusion
  • Other types are a 6 or 12 minute walk test, Peak Flow (PF), Maximum Inspiratory Pressure/Maximum Expiratory Pressure (MIP/MEP), and Arterial Blood Gas (ABG) analysis

Lung Volumes, Capacities, and Predicted Values

  • Four primary lung volumes: Tidal Volume (VT), Inspiratory Reserve Volume (IRV), Expiratory Reserve Volume (ERV), Residual Volume (RV)
  • Four lung capacities: Vital Capacity (VC), Inspiratory Capacity (IC), Functional Residual Capacity (FRC), Total Lung Capacity (TLC)
  • Predicted values determined by Height, Age, Gender, and Race (HAGR)

Ideal Body Weight Calculation

  • For males: Ideal Body Weight (IBW) = 106 + (6 x Height in inches) / 2.2 = IBW in kg
  • For females: IBW = 105 + (5 x Height in inches) / 2.2 = IBW in kg

Full Pulmonary Function Test components

  • Includes Forced Vital Capacity (FVC), Slow Vital Capacity (SVC), Maximum Voluntary Ventilation (MVV), Residual Volume/Functional Residual Capacity (RV/FRC), Diffusing Capacity of the Lungs for Carbon Monoxide (DLCO) and Post FVC

Lung Volumes and Capacities Explained

  • Tidal Volume (TV): Volume of air entering or leaving lungs during a single breath
  • Inspiratory Reserve Volume (IRV): Extra volume of air that can be maximally inspired over and above the typical resting tidal volume
  • Inspiratory Capacity (IC): Maximum volume of air that can be inspired at the end of a normal quiet expiration, calculated as IC = IRV + TV
  • Expiratory Reserve Volume (ERV): Extra volume of air that can be actively expired by maximal contraction beyond the normal volume of air after a resting tidal volume
  • Residual Volume (RV): Minimum volume of air remaining in the lungs even after a maximal expiration

Purposes of Pulmonary Function Testing (Indications)

  • Identify and quantify changes in pulmonary function due to disease
  • Evaluate the effectiveness of therapy
  • Perform epidemiological surveillance for pulmonary disease
  • Assess patients for the risk of postoperative complications
  • Determine pulmonary disability

Pathophysiologic Patterns in Pulmonary Disease

  • Two major categories of pulmonary disease: obstructive and restrictive
  • Obstructive diseases primary abnormality is increased airways resistance
  • Restrictive diseases primary problem is a decrease in either lung compliance or lung volumes or both
  • Some pulmonary diseases can cause both obstructive and restrictive impairments

PFT Equipment Types

  • Volume-measuring devices which are generically termed Spirometers
  • Flow-measuring devices which are called Pneumotachometers

Quality Assurance Elements

  • Accuracy and precision of measuring instruments
  • Performance of Respiratory Therapist (RT)
  • Test results when measuring against a known standard

Key Principles of Measurement

  • Most pulmonary function laboratories have 3 key components
  • Spirometry to measure airway mechanics
  • Measurements of lung volumes and capacities
  • Diffusion capacity measurements
  • All 3 test components are required to identify the presence and degree of pulmonary impairment

Spirometry Tests

  • Forced Vital Capacity (FVC)
  • Forced Expiratory Volume in 1 second (FEV₁)
  • Other forced expiratory flow measurements
  • Maximum Voluntary Ventilation

Forced Vital Capacity (FVC)

  • A common test that relies on patient effort and cooperation
  • Requires careful patient instruction
  • Requires at least 3 acceptable maneuvers to ensure validity

Important Spirometry Measures

  • FEV1 represents the volume of gas exhaled in the first second of an FVC maneuver
  • FEV1/FVC is calculated by dividing the largest FEV1 by the largest FVC
  • FEF200-1200 is the average flow rate early in the FVC
  • FEF25-75 is a measure of flow during the middle portion of the test
  • PEFR (Peak Expiratory Flow Rate) represents the highest point on a flow-volume graph

Maximal Voluntary Ventilation (MVV)

  • An effort-dependent test where the patient is asked to breathe deeply and quickly for 12 seconds
  • Results reflect patient effort, function of respiratory muscles, chest wall ability to expand, and patency of airways

Quality Assurance of Spirometry

  • A 3.0 L syringe is used for accuracy and precision of volume or flow measurements
  • Multiple strokes at various injection speeds
  • The average volume should be within +/- 3% standard
  • 95% expected performance range should be determined
  • Technologist performance should be observed and reviewed periodically

Significance of Spirometry Results

  • Normal FEV₁ is 5.6 L for an average 20-year-old man
  • FEV₁ is reduced with both obstructive and restrictive lung disease
  • FEV1/FVC should normally be at least 70%
    • Reduced with obstructive disease
    • Normal with restrictive disease
  • Other measures of expiratory flow are also reduced when obstructive disease is present
  • Normal MVV for males is 160 to 180 L/min and slightly lower in females
  • MVV is reduced in patients with moderate to severe obstructive lung disease
  • MVV may be normal or slightly reduced in patients with restrictive disease
  • Undernourished patients may have reduced MVV

Reversibility Testing

  • If obstruction is present, reversibility must be evaluated with spirometry
  • Spirometry is performed before and after therapy, with a bronchodilator administered typically via small-volume nebulizer or Metered Dose Inhaler (MDI)
  • Criteria for reversibility include an increase of 12% and 200 ml from predose in FEV₁ and/or FVC

Techniques for Measuring Residual Volume (RV)

  • Helium dilution is based on the fact that a known amount of helium will be diluted by the size of the patient's RV
  • Nitrogen washout is based on the fact that 79% of RV is nitrogen, Volume of nitrogen exhaled ÷ 0.79 = RV
  • Body box applies Boyle's law to measure RV

Key Interpretation Rule of Thumb

  • An FEV1/FVC (FEV1%) < 70% always indicates an obstructive disorder.
  • An FVC < 80% predicted in combination with a normal or high FEV1% defines a restrictive disorder.

Contraindications to Pulmonary Function Testing

  • Hemoptysis of unknown origin
  • Pneumothorax
  • Unstable cardiovascular status
  • Thoracic, abdominal, or cerebral aneurysms
  • Recent eye surgery
  • Acute disease processes
  • Recent surgery of thorax or abdomen

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