Podcast
Questions and Answers
The body's reaction to damage or threat, involving various physiological changes, is known as a ______ reaction.
The body's reaction to damage or threat, involving various physiological changes, is known as a ______ reaction.
stress
Stressors can only be psychological, such as sadness about job loss.
Stressors can only be psychological, such as sadness about job loss.
False (B)
Which of the following is NOT a biological concept of stress?
Which of the following is NOT a biological concept of stress?
What are two physiological changes associated with stress reactions?
What are two physiological changes associated with stress reactions?
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Match the stress concepts with their corresponding theorists:
Match the stress concepts with their corresponding theorists:
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What hormone is referred to as the 'cuddle/bonding hormone'?
What hormone is referred to as the 'cuddle/bonding hormone'?
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Chronic stress has no harmful effects on the body.
Chronic stress has no harmful effects on the body.
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Name one effect that oxytocin has on interpersonal relationships.
Name one effect that oxytocin has on interpersonal relationships.
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Chronic stress leads to a harmful reaction known as __________.
Chronic stress leads to a harmful reaction known as __________.
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Match the following effects with the corresponding hormones:
Match the following effects with the corresponding hormones:
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What is the primary physiological measure for stress?
What is the primary physiological measure for stress?
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The fight or flight response occurs only in response to long-term stressors.
The fight or flight response occurs only in response to long-term stressors.
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What system is activated during the stress response?
What system is activated during the stress response?
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Stress responses are initiated in the ______ part of the brain.
Stress responses are initiated in the ______ part of the brain.
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What is chronic pain defined as?
What is chronic pain defined as?
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Match the components of the stress process with their definitions:
Match the components of the stress process with their definitions:
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Chronic primary pain can occur with identified biological or psychological contributors.
Chronic primary pain can occur with identified biological or psychological contributors.
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Which of the following statements best describes the role of coping mechanisms in stress?
Which of the following statements best describes the role of coping mechanisms in stress?
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Glucocorticoids are primarily associated with long-term stress response.
Glucocorticoids are primarily associated with long-term stress response.
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What are the three factors that contribute to chronic pain syndromes?
What are the three factors that contribute to chronic pain syndromes?
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What is the main purpose of the fight-or-flight response?
What is the main purpose of the fight-or-flight response?
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Phantom pain primarily occurs in an ______ part of the body.
Phantom pain primarily occurs in an ______ part of the body.
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Match the following types of chronic pain with their definitions:
Match the following types of chronic pain with their definitions:
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What is a common sensation experienced in phantom pain?
What is a common sensation experienced in phantom pain?
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Chronic pain can only be diagnosed when physical causes are identified.
Chronic pain can only be diagnosed when physical causes are identified.
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What causes phantom pain primarily?
What causes phantom pain primarily?
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What is the term for the intensity level of a physical stimulus at which the stimulus is consciously perceived?
What is the term for the intensity level of a physical stimulus at which the stimulus is consciously perceived?
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Chronic pain is defined as intermittent pain that lasts at least six months.
Chronic pain is defined as intermittent pain that lasts at least six months.
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What are the three stages of chronic pain described in the content?
What are the three stages of chronic pain described in the content?
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Persistent pain disorder in ICD-10 is classified as ___.
Persistent pain disorder in ICD-10 is classified as ___.
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Subjects with high self-efficacy expectations tend to tolerate pain how?
Subjects with high self-efficacy expectations tend to tolerate pain how?
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The term 'learned helplessness' pertains to a chronic pain patient relying solely on adequate medication.
The term 'learned helplessness' pertains to a chronic pain patient relying solely on adequate medication.
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What are the two classifications of chronic pain in ICD-11 mentioned in the content?
What are the two classifications of chronic pain in ICD-11 mentioned in the content?
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Pain is described as an unpleasant sensory and emotional experience associated with actual or potential ___ damage.
Pain is described as an unpleasant sensory and emotional experience associated with actual or potential ___ damage.
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Match the following types of pain with their definitions:
Match the following types of pain with their definitions:
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Which factor contributes to altered membrane properties and increased excitability of postsynaptic nociceptive neurons?
Which factor contributes to altered membrane properties and increased excitability of postsynaptic nociceptive neurons?
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What is the primary effect of activating the sympathetic nervous system?
What is the primary effect of activating the sympathetic nervous system?
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The parasympathetic nervous system is responsible for the 'fight or flight' response.
The parasympathetic nervous system is responsible for the 'fight or flight' response.
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What does CRH stand for in the context of the HPA axis?
What does CRH stand for in the context of the HPA axis?
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Activation of the HPA axis leads to the secretion of __________ from the adrenal cortex.
Activation of the HPA axis leads to the secretion of __________ from the adrenal cortex.
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Match the following hormones to their corresponding glands:
Match the following hormones to their corresponding glands:
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Which of the following is NOT a result of the Trier Social Stress Test?
Which of the following is NOT a result of the Trier Social Stress Test?
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The parasympathetic nervous system primarily promotes body functions and relaxation.
The parasympathetic nervous system primarily promotes body functions and relaxation.
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What is the central aspect of the Trier Social Stress Test?
What is the central aspect of the Trier Social Stress Test?
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Flashcards
Allergic Rhinitis
Allergic Rhinitis
An allergic reaction causing nasal congestion and sneezing.
Autoimmune Disease
Autoimmune Disease
Condition where the immune system attacks the body's own cells.
Type 1 Diabetes
Type 1 Diabetes
Autoimmune disease where insulin-producing pancreatic cells are destroyed.
Stress Reaction
Stress Reaction
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Short-term Stress
Short-term Stress
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Chronic Pain Definition
Chronic Pain Definition
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Causes of Chronic Pain
Causes of Chronic Pain
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Chronic Primary Pain
Chronic Primary Pain
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Diagnosis of Chronic Pain
Diagnosis of Chronic Pain
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Phantom Pain Definition
Phantom Pain Definition
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Cause of Phantom Pain
Cause of Phantom Pain
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Internal Representation of Body
Internal Representation of Body
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Types of Chronic Pain
Types of Chronic Pain
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Stressor
Stressor
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Stress response
Stress response
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Coping mechanisms
Coping mechanisms
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Sympathetic nervous system
Sympathetic nervous system
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Hypothalamic-pituitary-adrenal axis
Hypothalamic-pituitary-adrenal axis
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Glucocorticoids
Glucocorticoids
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Fight or flight response
Fight or flight response
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Redistribution of resources
Redistribution of resources
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Chronic Stress
Chronic Stress
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Oxytocin
Oxytocin
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Stress and Immune System
Stress and Immune System
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Allostatic Load
Allostatic Load
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Empathy and Stress
Empathy and Stress
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Parasympathetic Nervous System
Parasympathetic Nervous System
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HPA Axis
HPA Axis
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CRH
CRH
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ACTH
ACTH
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Cortisol
Cortisol
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Trier Social Stress Test
Trier Social Stress Test
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Stress Effects
Stress Effects
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Pain Sensitivity
Pain Sensitivity
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Perception Threshold
Perception Threshold
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Tolerance Threshold
Tolerance Threshold
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F45.4 Persistent Pain Disorder
F45.4 Persistent Pain Disorder
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Chronic Pain (ICD-11)
Chronic Pain (ICD-11)
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Learned Helplessness
Learned Helplessness
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Medication Misuse
Medication Misuse
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Ice Water Experiment
Ice Water Experiment
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Biological Plasticity
Biological Plasticity
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Study Notes
Pain Biopsychology
- This course is on pain and biopsychology.
- The presenter is Marla Joy Mierzejewski.
- The course is at the University of Europe for Applied Sciences.
Semester Schedule
- Week 1: Introduction to the Central Nervous System (CNS). (October 28, 2024)
- Week 2: Peripheral Nervous System and Neurons. (November 4, 2024)
- Week 3: Drugs, Psychiatric Disorders, and Sensory System 1. (November 11, 2024)
- Week 4: Sensory System 2, Movement, and Pain 1. (November 18, 2024)
- Week 5: Pain 2, Immune System, and Stress. (November 25, 2024)
- Week 6: Heart, Breath, and Hunger. (December 2, 2024)
- Week 7: Sleep, Sexuality, and Genetics. (December 9, 2024)
- Week 8: Methods and Recap. (December 16, 2024)
Recap
- Sensory systems: Visual, auditory, olfactory, gustatory, and haptic.
- Motor system: Basal ganglia, cerebellum, thalamus, brainstem, and spinal cord.
- Pain: Acute vs. chronic pain, pain diagnostics, neuroplasticity, and biofeedback.
Research
- Research in groups of 4-5 on how pain sensation and processing works.
- Research on nociceptors and their role.
- Research on brain areas essential for pain processing.
- Report findings within 10 minutes.
Pain Conduction
- Nociceptors perceive thermal, chemical, or mechanical stimuli potentially harmful.
- Nociceptors are not pain receptors.
- Stimuli trigger signals to spinal cord - >thalamus.
- Thalamus filters information, passing it on to lateral and medial systems and frontal cortex.
- Lateral system relays conscious pain perception to somatosensory cortex.
- Medial system processes pain's affective and subjective meanings through limbic system.
- Frontal cortex processes memories and experiences related to pain.
Chronic Pain Risk Factors
- Current stressors (work, family).
- Operant reinforcement (leads to stronger pain behaviors).
- Operant mechanisms (related to medication intake and activity design).
- Model learning.
- Attention processes.
- Iatrogenic influences: Over-diagnostics, incorrect information (rest, bed rest), or incorrect medication.
- First learning processes at the level of the posterior horn; Cerebral changes in the form of expanded representations in the somatosensory cortex, leading to somatosensory "pain memory".
Chronic Pain definition (Temporal, Spatial & Behavioral)
- Temporal: Intermittent (stage 1), continuous (stage 2), highly changing intensity (stage 3).
- Spatial/Localization: Limited to time / paraphrased (stage 1), extended to neighboring areas (stage 2/3).
- Behavioral: Adequate medication, doctor consultations, hospital/surgery (stage 1), partly abuse of medicines, change of doctor, hospital/surgery (stage 2-3)
Pain Disorder in ICD-10 & -11
- ICD-10 F45.4: Persistent pain disorder (at least 6 months of severe pain).
- ICD-11 MG30: Chronic pain. Primary pain (visceral, widespread, musculoskeletal, headache, orofacial), cancer related, postsurgical/post traumatic, secondary musculoskeletal, visceral, or neuropathic pain.
- Psychological and social factors influence chronic pain.
- Symptoms, Signs, or Clinical Findings (chronic pain, associated emotional distress, and functional disability) affect appropriate diagnoses.
Phantom Limb
- Pain that occurs in an amputated body part.
- Characterized by tingling sensations, touch and warmth/cold.
- Related to changes in the brain's nervous system (functional reorganization of somatosensory cortex; internal representation remains intact).
- Damaged neurons form neuroma and generate action potentials.
Pain Therapy
- Acute pain: Tablets, pain pumps, appropriate activity and physiotherapy are used.
- Phantom pain: Medication, prosthesis, and mirror therapy are used.
- Chronic pain: Electromyography biofeedback, physiotherapy, relaxation method, cognitive behavioral therapy, imagination, and mindfulness are used.
Immune System
- Brainstorming topics: Immune system function; Composition of the immune system; Influence of the immune system; Problems with malfunctioning.
- Reading material: Innate and adaptive immune systems and associated questions.
- Study topics: Protective function, Innate immune system, Adaptive immune system.
Immune System and Vaccination
- Principle of vaccination: Injection of killed or weakened pathogens.
- Immune response: Body reacts by producing antibodies and memory cells to prepare for real pathogen encounter.
- Covid-19 and Vaccination: The vaccination against Covid-19 generates an immune response, reducing the chance of severe illness and death, and minimizes chances of spreading the virus.
Immune System - Infection vs. Vaccination & Measles
- Measles: High infectivity, epidemic risk, potential serious consequences from infection, as opposed to vaccination.
- Research (in groups of 4-5) should be done on the correlation between measles vaccination and autism in the U.S.
Disorders of the Immune System
- Primary immune deficiencies: Born with a weak immune system.
- Acquired immune deficiencies: Resulting from a disease or medicine that weakens the immune system.
- Overactive immune systems: Can cause allergic reactions (rhinitis, asthma, eczema).
- Autoimmune disorders: Immune system attacks the body's own cells (type 1 diabetes, rheumatoid arthritis).
Stress
- Brainstorming topics: Identifying stressors; How to recognize stress; Discussion within small groups.
- Stress definition: Body reactants with physiological change in response to stressor.
- Stress definition – biological: Fight or flight response, General Adaptation Syndrome, and Allostatic Load.
- Stress definition – psychological: Critical Life Events, Transactional stress theory, Theory of Resource Conservation.
- Stress components: Stressor (environmental stimulus), Detection of threat (unconscious/conscious), Stress response (activation of various biological systems).
- Stress Location in the Brain: Hypothalamic-pituitary-adrenocortical axis (HPA axis); Corticotropin releasing hormone (CRH), Adrenocorticotropic hormone (ACTH), and Cortisol.
- Stress and allostatic load: Allostasis, the body’s ability to adapt and maintain homeostasis during a stress response. Allostatic load represents consequences of the constant adaptation, damage to the body due to long-term stress exposure, or inefficient system response.
Immune System & Stress
- Short-term stress has a positive effect; Long-term stress weakens the immune system.
- Chronic stress, elevated cortisol levels and increased vulnerability to infections.
- Stress can reduce the number of natural killer cells and influence T- and B-lymphocytes.
- Communication/interactions between nervous system and immune system are relevant.
- Hippocampus is vulnerable to stress.
- More research is needed.
Research Topics
- Stress role in disease development (in groups of 4-5).
- HPA axis and the functions of CRH, ACTH, and Cortisol (in groups of 4–5).
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Description
Test your understanding of the body's response to stress and its physiological changes. This quiz will cover key concepts, theorists, and differentiate between biological and psychological stressors. Hone your knowledge on how stress affects both the mind and body.