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Questions and Answers
What is the primary function of the hypothalamic-pituitary-adrenal (HPA) axis?
What is the primary function of the hypothalamic-pituitary-adrenal (HPA) axis?
Which hormone is produced by the adrenal gland and plays a key role in the stress response?
Which hormone is produced by the adrenal gland and plays a key role in the stress response?
How does homeostasis differ from allostasis?
How does homeostasis differ from allostasis?
Which of these is NOT a component of the HPA axis?
Which of these is NOT a component of the HPA axis?
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Which of the following is NOT a component of the HPA axis?
Which of the following is NOT a component of the HPA axis?
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What is the role of the hypothalamus in the stress response?
What is the role of the hypothalamus in the stress response?
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What is the initial change observed in the body's response to acute stress?
What is the initial change observed in the body's response to acute stress?
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How can exercise be considered a stressor?
How can exercise be considered a stressor?
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What is the primary role of the pituitary gland in the stress response?
What is the primary role of the pituitary gland in the stress response?
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What is the primary role of the salience network during acute stress?
What is the primary role of the salience network during acute stress?
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Which of the following is NOT a consequence of the acute stress response?
Which of the following is NOT a consequence of the acute stress response?
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How can peripheral effects of exercise influence central mechanisms?
How can peripheral effects of exercise influence central mechanisms?
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Which of the following is TRUE regarding the effect of acute stress on gene transcription?
Which of the following is TRUE regarding the effect of acute stress on gene transcription?
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What is the function of the executive network in the context of acute stress?
What is the function of the executive network in the context of acute stress?
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Which of the following brain regions is NOT directly involved in the salience network?
Which of the following brain regions is NOT directly involved in the salience network?
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What is the PRIMARY distinction between the acute stress response and chronic stress?
What is the PRIMARY distinction between the acute stress response and chronic stress?
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Which of the following is NOT a neurotransmitter mentioned in the text that is affected by physical activity?
Which of the following is NOT a neurotransmitter mentioned in the text that is affected by physical activity?
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Which brain region is directly involved in modulating visual cortex activity due to physical activity?
Which brain region is directly involved in modulating visual cortex activity due to physical activity?
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What is the primary function of the basal forebrain, mentioned in the text, in relation to physical activity?
What is the primary function of the basal forebrain, mentioned in the text, in relation to physical activity?
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Which of the following is NOT a documented impact of exercise on the body, as suggested in the text?
Which of the following is NOT a documented impact of exercise on the body, as suggested in the text?
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How does physical activity impact mood according to the text?
How does physical activity impact mood according to the text?
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What is the primary difference between neurotrophic and neuromodulatory effects of exercise?
What is the primary difference between neurotrophic and neuromodulatory effects of exercise?
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Based on the provided information, how does the peripheral nervous system influence the central nervous system in response to exercise?
Based on the provided information, how does the peripheral nervous system influence the central nervous system in response to exercise?
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Which of the following statements BEST represents the central takeaway of the provided content?
Which of the following statements BEST represents the central takeaway of the provided content?
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What is the primary function of the sympathetic nervous system?
What is the primary function of the sympathetic nervous system?
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What is the main component of the central nervous system that receives and processes information from the body?
What is the main component of the central nervous system that receives and processes information from the body?
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Which of these is NOT a known neurotransmitter discussed in the text?
Which of these is NOT a known neurotransmitter discussed in the text?
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What type of effect can neurotransmitters have on the nervous system?
What type of effect can neurotransmitters have on the nervous system?
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What is the main function of myokines in the neurotrophic impacts of exercise?
What is the main function of myokines in the neurotrophic impacts of exercise?
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Which of the following is NOT a neurotrophic effect of exercise?
Which of the following is NOT a neurotrophic effect of exercise?
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What is the name of the selective membrane that separates the bloodstream from brain tissue?
What is the name of the selective membrane that separates the bloodstream from brain tissue?
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What is the primary difference between the peripheral and central nervous systems?
What is the primary difference between the peripheral and central nervous systems?
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How do myokines contribute to the neurotrophic effects of exercise?
How do myokines contribute to the neurotrophic effects of exercise?
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Which of these is NOT a component of the autonomic nervous system?
Which of these is NOT a component of the autonomic nervous system?
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What is the primary role of BDNF in the neurotrophic effects of exercise?
What is the primary role of BDNF in the neurotrophic effects of exercise?
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Which division of the autonomic nervous system is responsible for the "rest and digest" response?
Which division of the autonomic nervous system is responsible for the "rest and digest" response?
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Which of the following is a key difference between neurotrophic and neuromodulatory effects of exercise?
Which of the following is a key difference between neurotrophic and neuromodulatory effects of exercise?
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How does vigorous physical activity influence the release of IGF-1?
How does vigorous physical activity influence the release of IGF-1?
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What is the primary function of the skeletal motor nervous system?
What is the primary function of the skeletal motor nervous system?
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Which of the following is an example of a neuromodulatory effect of exercise?
Which of the following is an example of a neuromodulatory effect of exercise?
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How can exercise affect the blood-brain barrier?
How can exercise affect the blood-brain barrier?
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What are the two main ways that the central nervous system transmits signals?
What are the two main ways that the central nervous system transmits signals?
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What is the significance of the blood-brain barrier in relation to the effects of exercise?
What is the significance of the blood-brain barrier in relation to the effects of exercise?
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What is a common physiological response to stress?
What is a common physiological response to stress?
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Which of these is NOT a factor that could influence the interaction between the peripheral and central nervous systems?
Which of these is NOT a factor that could influence the interaction between the peripheral and central nervous systems?
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What two brain networks are proposed to have a tradeoff in functioning, according to the text?
What two brain networks are proposed to have a tradeoff in functioning, according to the text?
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What is a key aspect of the definition of stress as presented in the text?
What is a key aspect of the definition of stress as presented in the text?
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Flashcards
Body’s Regulatory Cycles
Body’s Regulatory Cycles
Biological processes that help adapt to stressors and challenges.
Homeostasis
Homeostasis
A feedback system maintaining stability through constancy.
Allostasis
Allostasis
A predictive system that anticipates demands and promotes stability through change.
HPA Axis
HPA Axis
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Hypothalamus
Hypothalamus
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Pituitary Gland
Pituitary Gland
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Adrenal Gland
Adrenal Gland
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Stress Response
Stress Response
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Acute Stress Response
Acute Stress Response
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Catecholamines
Catecholamines
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Corticosteroids
Corticosteroids
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Salience Network
Salience Network
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Executive Network
Executive Network
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Norepinephrine
Norepinephrine
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Cognition Impact
Cognition Impact
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Neurotrophic Effects
Neurotrophic Effects
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Examples of Neurotrophic Effects
Examples of Neurotrophic Effects
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Myokines
Myokines
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Insulin-like Growth Factor 1 (IGF-1)
Insulin-like Growth Factor 1 (IGF-1)
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Brain Derived Neurotrophic Factor (BDNF)
Brain Derived Neurotrophic Factor (BDNF)
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Neuromodulatory Effects
Neuromodulatory Effects
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Serotonin Release
Serotonin Release
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Peripheral Organ Effects
Peripheral Organ Effects
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DLPFC
DLPFC
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PPC
PPC
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Stress Definition
Stress Definition
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Peripheral Effects
Peripheral Effects
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Central Effects
Central Effects
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Motor Component
Motor Component
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Sensory Component
Sensory Component
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Autonomic Nervous System
Autonomic Nervous System
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Parasympathetic Nervous System
Parasympathetic Nervous System
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Sympathetic Nervous System
Sympathetic Nervous System
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Neurotransmitters
Neurotransmitters
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Blood-Brain Barrier
Blood-Brain Barrier
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Exercise Impact
Exercise Impact
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Neuromodulatory Impacts
Neuromodulatory Impacts
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Dopamine Release
Dopamine Release
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Ventral Tegmental Area
Ventral Tegmental Area
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Substantia Nigra
Substantia Nigra
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Acetylcholine
Acetylcholine
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Basal Forebrain
Basal Forebrain
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Peripheral and Central Effects
Peripheral and Central Effects
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Study Notes
Lecture 2: What Happens When We Move Our Bodies?
- The body's regulatory systems adapt to challenges and stressors.
- Exercise is a stressor that impacts both the peripheral and central nervous systems.
- Peripheral effects can influence central mechanisms.
- There are two main categories of central effects.
How Does the Body Regulate Itself?
- Homeostasis maintains stability through constancy.
- Allostasis is a predictive system that promotes stability through change.
- The body allocates just enough resources at the right time.
- Allostatic load results from chronically repeated or diverse stressors.
The Stress Response Aids Regulation
- The hypothalamic-pituitary-adrenal (HPA) axis controls the body's stress response.
- The hypothalamus manages the autonomic nervous system (e.g., breathing, heart rate).
- The pituitary gland releases hormones.
- The adrenal gland releases steroid hormones (e.g., cortisol), adrenaline, and noradrenaline.
- Stress triggers a chain reaction in the HPA axis affecting blood flow, respiration, metabolism, immune response, arousal.
- CRH (Corticotropin-releasing hormone) and ACTH (Adrenocorticotropic hormone) are key hormones in this process.
- Cortisol affects the immune system suppressing it.
How Does Our Body Respond to Acute Stress?
- Acute stressors cause dynamic neuroendocrine changes.
- Catecholamines (e.g., norepinephrine, dopamine) increase rapidly.
- Corticosteroids (e.g., cortisol) increase slowly.
- These changes affect cellular levels altering neural activity and gene transcription.
- Acute stress impacts cognitive function by affecting the tradeoff between the salience network and the executive control network.
Exercise as a Stressor
- Exercise impacts cognitive function and the body.
- Exercise has both peripheral and central effects.
Exercise Has Peripheral and Central Effects
- Peripheral effects are outside the head and spinal cord.
- The peripheral nervous system has two components: motor and sensory
- Motor component is responsible for voluntary movements.
- Somatic nervous system is responsible for voluntary movements.
- Central nervous system is between the ears and spinal cord.
- Autonomic nervous system regulates internal organs (eyes, digestive system, heart rate).
Autonomic Nervous System
- Can be divided into three components:
- Parasympathetic (rest and digest)
- Sympathetic (fight or flight)
- Enteric (manages digestion).
- Autonomic nervous system has effects on heart rate, pupils, saliva, airways, stomach, intestines, and digestion.
Central Nervous System
- The central nervous system includes the brain and spinal cord.
- Signaling occurs through electrical activity, neurochemical changes, and neurotransmitters.
- More than 100 known neurotransmitters including amino-acids, monoamines and peptides.
- The blood-brain barrier (BBB) is a key point of interaction between the peripheral and central nervous systems.
Exercise Impacts Central Nervous System
- Exercise has neurotrophic effects. These effects promote neurogenesis, proliferation, differentiation, and health of neurons.
- Exercise has neuromodulatory effects. These effects alter neural activity via electrochemical processes.
Exercise and Physical Activity Neurobiological Impacts
- Physical activity impacts peripheral organs which release hormones and growth factors into the bloodstream. Some of these compounds cross the BBB. Some examples include myokines (e.g., irisin and cathepsin), and IGF-1 (Insulin-like growth factor 1).
- Physical activity affects the hippocampus volume, releasing BDNF, and modulating neurotransmitter function.
- Physical activity affects brain neurotransmitters like serotonin, dopamine, and acetylcholine via the raphe nucleus, ventral tegmental area, substantia nigra,and basal forebrain.
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Description
Test your knowledge on the hypothalamic-pituitary-adrenal (HPA) axis and its role in stress response. This quiz covers essential concepts such as the functions of various hormones, the differences between homeostasis and allostasis, and the impact of stress on gene transcription. Perfect for psychology students looking to deepen their understanding of stress mechanisms.