Podcast
Questions and Answers
What is the primary reason why the frontal lobes are of most interest to psychotherapy interventions like CBT?
What is the primary reason why the frontal lobes are of most interest to psychotherapy interventions like CBT?
What is the function of catechol-o-methyltransferase?
What is the function of catechol-o-methyltransferase?
What is one of the executive functions associated with the PFC in the frontal lobes?
What is one of the executive functions associated with the PFC in the frontal lobes?
What is NOT a function associated with the frontal lobes?
What is NOT a function associated with the frontal lobes?
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What is the product of the reaction catalyzed by monoamine oxidase?
What is the product of the reaction catalyzed by monoamine oxidase?
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What is the substrate for monoamine oxidase?
What is the substrate for monoamine oxidase?
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What is the term used to describe the ability to regulate one's emotions, which is associated with the frontal lobes?
What is the term used to describe the ability to regulate one's emotions, which is associated with the frontal lobes?
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What is the difference between the functions of catechol-o-methyltransferase and monoamine oxidase?
What is the difference between the functions of catechol-o-methyltransferase and monoamine oxidase?
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According to the content, what is the outcome of having healthy frontal lobe function?
According to the content, what is the outcome of having healthy frontal lobe function?
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Which of the following is NOT a metabolite of norepinephrine?
Which of the following is NOT a metabolite of norepinephrine?
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What happens when reuptake or enzyme degradation is blocked?
What happens when reuptake or enzyme degradation is blocked?
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What is the primary function of enzyme degradation in neurotransmission?
What is the primary function of enzyme degradation in neurotransmission?
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What is the main purpose of reuptake in neurotransmission?
What is the main purpose of reuptake in neurotransmission?
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What is the net result of blocking reuptake and enzyme degradation?
What is the net result of blocking reuptake and enzyme degradation?
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What is the primary mechanism of regulating neurotransmitter activity?
What is the primary mechanism of regulating neurotransmitter activity?
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What type of receptor does Memantine antagonize?
What type of receptor does Memantine antagonize?
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What is the primary mechanism of action of Memantine in the treatment of Alzheimer's disease?
What is the primary mechanism of action of Memantine in the treatment of Alzheimer's disease?
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What is the indication for Memantine (Namenda) in the treatment of Alzheimer's disease?
What is the indication for Memantine (Namenda) in the treatment of Alzheimer's disease?
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What is the name of the brand-name medication that is an NMDA receptor antagonist?
What is the name of the brand-name medication that is an NMDA receptor antagonist?
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What is the relationship between Memantine and GABA?
What is the relationship between Memantine and GABA?
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The left OFC is associated with emotions that are
The left OFC is associated with emotions that are
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The right OFC is associated with emotions that are
The right OFC is associated with emotions that are
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What is the primary difference between the left and right OFC?
What is the primary difference between the left and right OFC?
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Which of the following is NOT a function of the left OFC?
Which of the following is NOT a function of the left OFC?
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What can be inferred about the hemispherical differences in the OFC?
What can be inferred about the hemispherical differences in the OFC?
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Study Notes
OFC Hemispherical Differences
- Left OFC is associated with positive emotions
- Right OFC is associated with more negative emotions
Memantine (Namenda)
- NMDA receptor antagonist
- Blocks influx of calcium
- Indicated for patients with moderate to severe Alzheimer's disease
Neurotransmitter Regulation
- GABA: inhibitory neurotransmitter
- Catechol-o-methyltransferase: methylates norepinephrine and intermediate metabolites
- Monoamine oxidase: deaminates norepinephrine and normetanephrine to their corresponding aldehydes
- Reuptake or enzyme degradation blockage: increases neurotransmitter concentration in the synaptic cleft
Frontal Lobes and PFC
- Frontal lobes: home to the prefrontal cortex (PFC)
- PFC: involved in executive functions, including:
- Concentration
- Organization
- Judgment
- Reasoning
- Decision-making
- Creativity
- Emotional regulation
- Social-relational abilities
- Abstract thinking
- Importance of PFC in healthy relationships with oneself and others
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Description
This quiz covers the differences in brain hemispheres and their relation to emotions, the effects of Memantine on Alzheimer's disease, and the regulation of neurotransmitters like GABA and norepinephrine.