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Questions and Answers
Which of the following BEST describes the key characteristic of episodic memory?
Which of the following BEST describes the key characteristic of episodic memory?
Who is credited with providing the widely accepted definition of episodic memory?
Who is credited with providing the widely accepted definition of episodic memory?
The definition of episodic memory highlights its association with which of the following?
The definition of episodic memory highlights its association with which of the following?
What is NOT a crucial element in the definition of episodic memory?
What is NOT a crucial element in the definition of episodic memory?
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Which of the following is an example of an episodic memory?
Which of the following is an example of an episodic memory?
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How does episodic memory differ from semantic memory?
How does episodic memory differ from semantic memory?
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Which of the following is NOT a key component of episodic memory as a spatiotemporal trajectory?
Which of the following is NOT a key component of episodic memory as a spatiotemporal trajectory?
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What does the term 'mental time travel' refer to in the context of episodic memory?
What does the term 'mental time travel' refer to in the context of episodic memory?
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How does the brain represent a trajectory through space and time in episodic memory?
How does the brain represent a trajectory through space and time in episodic memory?
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What is the main consequence of bilateral medial temporal lobe resection, as evidenced by HM's case?
What is the main consequence of bilateral medial temporal lobe resection, as evidenced by HM's case?
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What does the term 'temporally graded' refer to regarding retrograde amnesia in HM's case?
What does the term 'temporally graded' refer to regarding retrograde amnesia in HM's case?
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Which type of memory is most likely to be impaired by damage to the hippocampus?
Which type of memory is most likely to be impaired by damage to the hippocampus?
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How does procedural memory differ from episodic memory?
How does procedural memory differ from episodic memory?
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What is a key characteristic of episodic memory that differentiates it from other memory types?
What is a key characteristic of episodic memory that differentiates it from other memory types?
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What is a 'spatiotemporal trajectory' in the context of episodic memory?
What is a 'spatiotemporal trajectory' in the context of episodic memory?
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Which aspect of memory is primarily preserved in individuals with hippocampal damage?
Which aspect of memory is primarily preserved in individuals with hippocampal damage?
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What does performance in the Brown-Peterson Task assess?
What does performance in the Brown-Peterson Task assess?
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What type of memory impairment does not show permanent deficits in initial studies with monkey lesions?
What type of memory impairment does not show permanent deficits in initial studies with monkey lesions?
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What did fMRI studies reveal about hippocampal activation?
What did fMRI studies reveal about hippocampal activation?
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What unique ability do scrub jays exhibit regarding memory?
What unique ability do scrub jays exhibit regarding memory?
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Which of the following findings about hippocampal lesions is correct?
Which of the following findings about hippocampal lesions is correct?
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What was a significant conclusion from studies on patient HM?
What was a significant conclusion from studies on patient HM?
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What does the involvement of the fornix signify in memory processing?
What does the involvement of the fornix signify in memory processing?
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What is the primary role of glutamate in neuronal communication?
What is the primary role of glutamate in neuronal communication?
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What mechanism drives the persistent spiking phenomenon in entorhinal neurons?
What mechanism drives the persistent spiking phenomenon in entorhinal neurons?
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How do stellate cells in the medial entorhinal cortex influence oscillatory activity?
How do stellate cells in the medial entorhinal cortex influence oscillatory activity?
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What is the primary function of spike frequency accommodation in neurons?
What is the primary function of spike frequency accommodation in neurons?
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What role does the h-current play in neuronal function?
What role does the h-current play in neuronal function?
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What part of the brain is responsible for processing spatial location in the context of episodic memory?
What part of the brain is responsible for processing spatial location in the context of episodic memory?
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What is the significance of membrane potential oscillations in neurons?
What is the significance of membrane potential oscillations in neurons?
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Which structure receives convergent input from both the lateral and medial entorhinal cortex?
Which structure receives convergent input from both the lateral and medial entorhinal cortex?
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Which type of neurotransmitter action is associated with GABA?
Which type of neurotransmitter action is associated with GABA?
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What process links spatial context with specific events to form episodic memories?
What process links spatial context with specific events to form episodic memories?
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What is meant by graded spiking in entorhinal cortex neurons?
What is meant by graded spiking in entorhinal cortex neurons?
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Which ions are primarily involved in maintaining the resting potential of hippocampal neurons?
Which ions are primarily involved in maintaining the resting potential of hippocampal neurons?
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What is the primary role of the hippocampus in episodic memory formation?
What is the primary role of the hippocampus in episodic memory formation?
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Which of the following best describes the function of the CA3 region in episodic memory?
Which of the following best describes the function of the CA3 region in episodic memory?
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What aspect of neuronal behavior is crucial for the support of episodic memory?
What aspect of neuronal behavior is crucial for the support of episodic memory?
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Episodic memories can be triggered by which mechanism?
Episodic memories can be triggered by which mechanism?
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What is the primary purpose of the delayed spatial alternation task in rodents?
What is the primary purpose of the delayed spatial alternation task in rodents?
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Which brain structures are indicated to impair performance in delayed spatial alternation tasks when lesioned?
Which brain structures are indicated to impair performance in delayed spatial alternation tasks when lesioned?
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What is the task involved in the Morris Water Maze designed to assess?
What is the task involved in the Morris Water Maze designed to assess?
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How does the forced choice delayed alternation task differ from other alternation tasks?
How does the forced choice delayed alternation task differ from other alternation tasks?
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In the context of object investigation time, what aspect of memory is being assessed?
In the context of object investigation time, what aspect of memory is being assessed?
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What happens to rat performance in the eight-arm radial maze when the hippocampus is lesioned?
What happens to rat performance in the eight-arm radial maze when the hippocampus is lesioned?
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What is demonstrated through probe trials in the Morris Water Maze?
What is demonstrated through probe trials in the Morris Water Maze?
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What best describes the role of the hippocampus in episodic memory?
What best describes the role of the hippocampus in episodic memory?
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What characterizes the spontaneous alternation task for rodents?
What characterizes the spontaneous alternation task for rodents?
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What effect do fornix lesions have on rats in spatial reversal tasks?
What effect do fornix lesions have on rats in spatial reversal tasks?
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Flashcards
Episodic Memory
Episodic Memory
Recollection of specific sensory experiences tied to times and places.
Sensory Experiences
Sensory Experiences
Inputs from the senses that help create memories.
Time in Episodic Memory
Time in Episodic Memory
Specific moments when events occur in episodic memory.
Place in Episodic Memory
Place in Episodic Memory
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Tulving's Definition
Tulving's Definition
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Semantic Memory
Semantic Memory
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Procedural Memory
Procedural Memory
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Working Memory
Working Memory
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Mental Time Travel
Mental Time Travel
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Spatiotemporal Trajectory
Spatiotemporal Trajectory
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Key Components of Episodic Memory
Key Components of Episodic Memory
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HM Case Study
HM Case Study
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Anterograde Amnesia
Anterograde Amnesia
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Retrograde Amnesia
Retrograde Amnesia
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Delayed Spatial Alternation
Delayed Spatial Alternation
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Rewarded Alternation Task
Rewarded Alternation Task
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Forced Choice Delayed Alternation
Forced Choice Delayed Alternation
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Spatial Reversal
Spatial Reversal
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Eight-Arm Radial Maze
Eight-Arm Radial Maze
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Morris Water Maze
Morris Water Maze
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Probe Trials
Probe Trials
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Object Investigation Time
Object Investigation Time
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Hippocampal Lesions
Hippocampal Lesions
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Episodic Memory in Rats
Episodic Memory in Rats
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Parallel Streams
Parallel Streams
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Lateral Entorhinal Cortex
Lateral Entorhinal Cortex
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Medial Entorhinal Cortex
Medial Entorhinal Cortex
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Role of CA1
Role of CA1
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Reciprocal Richness
Reciprocal Richness
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Convergence Mechanism
Convergence Mechanism
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Ion Concentration Dynamics
Ion Concentration Dynamics
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CA3 and Dentate Gyrus
CA3 and Dentate Gyrus
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Hippocampal Damage Effects
Hippocampal Damage Effects
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Working Memory Capacity
Working Memory Capacity
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Brown-Peterson Task
Brown-Peterson Task
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Hippocampus and Memory
Hippocampus and Memory
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Episodic-like Memory in Birds
Episodic-like Memory in Birds
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Primates and Episodic Memory
Primates and Episodic Memory
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Impact of Lesions
Impact of Lesions
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Fornix in Memory Processing
Fornix in Memory Processing
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Action Potential
Action Potential
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Neurotransmitter Effects
Neurotransmitter Effects
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Persistent Spiking
Persistent Spiking
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CAL Current
CAL Current
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Oscillatory Activity
Oscillatory Activity
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Theta-Frequency Oscillations
Theta-Frequency Oscillations
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Spike Frequency Accommodation
Spike Frequency Accommodation
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h-Current
h-Current
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Study Notes
Chapter 1: Behavioral Dynamics of Episodic Memory
- Definition: Episodic memory is the recollection of specific sensory experiences tied to particular times and places. It involves a sense of experiencing the event as if reliving it, represented as short time slices.
- Contrast with other memory types:
- Semantic Memory: General knowledge and facts, doesn't involve specific experiences or time/place.
- Procedural Memory: Knowing how to perform tasks, often motor skills. Doesn't rely on conscious recollection of time-specific experiences.
- Working Memory: Actively holds and manipulates information in the short term, not tied to past experiences.
- Comparison to Mental Time Travel: Episodic memory involves mentally reliving past events.
- Episodic Memory as a Spatiotemporal Trajectory: Episodic memory involves encoding and retrieving experiences as a continuous sequence of spatial and temporal information.
- Key Components:
- Absolute location: Specific places visited.
- Movement and direction: The trajectory captured.
- Timing: Relating events to time, including duration at each location.
- Key Components:
Chapter 2: Neural Dynamics of Episodic Memory
- Anatomical Circuits:
- Hippocampus: Central hub for encoding and retrieving episodic memories. Crucial for spatial and contextual memory.
- Medial Temporal Lobe (MTL): Includes entorhinal, perirhinal, and parahippocampal cortices. Processes and relays episodic information to the hippocampus.
- Fornix: Major white matter pathway connecting hippocampus to mammillary bodies and anterior thalamus, supporting memory consolidation.
- Mammillary Bodies & Anterior Thalamus: Involved in relaying hippocampal outputs and integrating memory with executive and attentional processes.
- Prefrontal Cortex: Regulates memory retrieval, organization, and decision-making related to episodic recall.
- Principles of Connectivity:
- Consistent Scales of Space and Time: Hierarchical spatial coding across different scales (e.g., room to object). Maintains consistent spatiotemporal maps for accurate retrieval.
- Topographic Organization: Dorsal and ventral entorhinal cortex projects to dorsal and ventral hippocampus, respectively, creating a structured flow of spatial-temporal information.
Network Oscillations
- Theta Rhythm Oscillations: 4-10 Hz oscillations in hippocampus and entorhinal cortex, correlate with movement, arousal, and attention. Stronger theta power enhances learning. Theta frequency modulates with speed (velocity coding).
- Gamma and Beta Rhythm Oscillations: Higher frequencies than theta, prominent in the neocortex during arousal and attention. Desynchronization (reduction in large-amplitude slow waves) indicates active cognitive processing. Theta-nested gamma: Gamma oscillations align with theta phases, supporting hippocampal interactions.
Cellular Mechanisms and Episodic Memory
- Neuronal Properties: Spiking activity, synaptic potentials and oscillatory dynamics support episodic memory in hippocampus and entorhinal cortex. Neurons maintain a resting potential, changes in ion conductance drive depolarization or hyperpolarization.
- Action Potentials: Neurons triggers rapid spike-followed by potassium efflux to restore resting potential.
- Glutamate & GABA: Glutamate excites neurons, while GABA inhibits. Acetylcholine modulates spiking and synaptic plasticity.
- Persistent Spiking: Neurons continue firing after a stimulus ends, even when synaptic transmission is blocked. Driven by calcium-activated non-specific cation (CAN) current maintaining depolarization.
- Membrane Potential Oscillations and Resonance: Neurons in entorhinal cortex resonate at specific frequencies, contributing to coding space and time.
Spiking Patterns
- Place Cells: Neurons in the hippocampus that fire selectively when an animal is in a specific spatial location, independent of rewards or specific tasks. Maintain consistent firing locations in consistent environments, but remap in new environments or when task conditions change. They exhibit directional selectivity.
- Context-Dependent Firing/Memory Space Theory: Hippocampal neurons encode a multi-dimensional "memory space", integrating spatial and contextual information across an episode.
- Splitter Cells: Hippocampal neurons differentiate firing based on past or future trajectories.
- Oscillatory Interference Model of Grid Cells: Oscillatory interference model predicts multiple firing fields. Grid cell spacing increases along the dorsal-ventral axis due to a decrease in intrinsic oscillation frequency.
Other Key Features
- Theta Phase Precession: Hippocampal place cells fire at progressively earlier theta phases as an animal moves.
- Grid Cells: Neurons in the medial entorhinal cortex that fire at multiple locations arranged in a hexagonal grid pattern. Provide a spatial coordinate system.
- Head Direction Cells: Neurons that fire when an animal's head is oriented in a specific direction.
- Adaptive Spatial Coding: Grid and place cells adjust their firing patterns in response to environmental changes.
- Episodic Replay: Hippocampal neurons replay sequences of past experiences.
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Description
Explore the fascinating world of episodic memory in this quiz based on Chapter 1. Understand how episodic memory differs from semantic, procedural, and working memory, and learn about its characteristics and significance in cognitive psychology. Test your knowledge about the spatiotemporal aspects of this type of memory.