Psychology Chapter 1: Episodic Memory Dynamics
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Questions and Answers

Which of the following BEST describes the key characteristic of episodic memory?

  • It focuses on the recollection of specific events tied to time and place. (correct)
  • It is primarily used for language comprehension and vocabulary.
  • It involves the storage of general knowledge and facts.
  • It is primarily responsible for procedural skills and habits.
  • Who is credited with providing the widely accepted definition of episodic memory?

  • Endel Tulving (correct)
  • Noam Chomsky
  • Jean Piaget
  • B.F. Skinner
  • The definition of episodic memory highlights its association with which of the following?

  • Working Memory
  • Procedural Memory
  • Sensory Memory (correct)
  • Semantic Memory
  • What is NOT a crucial element in the definition of episodic memory?

    <p>Association with emotional states (A)</p> Signup and view all the answers

    Which of the following is an example of an episodic memory?

    <p>Remembering your first day of school. (B)</p> Signup and view all the answers

    How does episodic memory differ from semantic memory?

    <p>Episodic memory involves specific experiences and context, while semantic memory relates to general knowledge and facts. (A)</p> Signup and view all the answers

    Which of the following is NOT a key component of episodic memory as a spatiotemporal trajectory?

    <p>Emotional intensity (C)</p> Signup and view all the answers

    What does the term 'mental time travel' refer to in the context of episodic memory?

    <p>The ability to remember specific moments in time and vividly experience them again. (C)</p> Signup and view all the answers

    How does the brain represent a trajectory through space and time in episodic memory?

    <p>By encoding the relative timing of rhythmic activity in different neuron populations. (D)</p> Signup and view all the answers

    What is the main consequence of bilateral medial temporal lobe resection, as evidenced by HM's case?

    <p>Inability to form new memories. (D)</p> Signup and view all the answers

    What does the term 'temporally graded' refer to regarding retrograde amnesia in HM's case?

    <p>Newer memories are more affected than older memories. (D)</p> Signup and view all the answers

    Which type of memory is most likely to be impaired by damage to the hippocampus?

    <p>Episodic memory (C)</p> Signup and view all the answers

    How does procedural memory differ from episodic memory?

    <p>Procedural memory involves knowing how to do things, while episodic memory involves remembering specific experiences. (C)</p> Signup and view all the answers

    What is a key characteristic of episodic memory that differentiates it from other memory types?

    <p>Involves remembering specific experiences, often linked to a particular time and place. (B)</p> Signup and view all the answers

    What is a 'spatiotemporal trajectory' in the context of episodic memory?

    <p>The continuous sequence of spatial and temporal information associated with an experience. (C)</p> Signup and view all the answers

    Which aspect of memory is primarily preserved in individuals with hippocampal damage?

    <p>Working memory (B)</p> Signup and view all the answers

    What does performance in the Brown-Peterson Task assess?

    <p>Short-term memory decay (C)</p> Signup and view all the answers

    What type of memory impairment does not show permanent deficits in initial studies with monkey lesions?

    <p>Entorhinal lesions (A)</p> Signup and view all the answers

    What did fMRI studies reveal about hippocampal activation?

    <p>It shows robust activation during complex memory tasks. (C)</p> Signup and view all the answers

    What unique ability do scrub jays exhibit regarding memory?

    <p>They plan for future needs related to food storage. (D)</p> Signup and view all the answers

    Which of the following findings about hippocampal lesions is correct?

    <p>They produce distinct effects based on the area damaged. (B)</p> Signup and view all the answers

    What was a significant conclusion from studies on patient HM?

    <p>The hippocampus is critical for memory formation. (D)</p> Signup and view all the answers

    What does the involvement of the fornix signify in memory processing?

    <p>It is involved in coordination between different memory systems. (A)</p> Signup and view all the answers

    What is the primary role of glutamate in neuronal communication?

    <p>Excitement of neurons via sodium and potassium channels (C)</p> Signup and view all the answers

    What mechanism drives the persistent spiking phenomenon in entorhinal neurons?

    <p>Calcium-activated nonspecific cation current (D)</p> Signup and view all the answers

    How do stellate cells in the medial entorhinal cortex influence oscillatory activity?

    <p>By exhibiting strong oscillatory activity and resonance (A)</p> Signup and view all the answers

    What is the primary function of spike frequency accommodation in neurons?

    <p>To adapt neuronal activity to prior input levels (B)</p> Signup and view all the answers

    What role does the h-current play in neuronal function?

    <p>Allowing neurons to rebound from inhibition and generate oscillations (D)</p> Signup and view all the answers

    What part of the brain is responsible for processing spatial location in the context of episodic memory?

    <p>Medial entorhinal cortex (D)</p> Signup and view all the answers

    What is the significance of membrane potential oscillations in neurons?

    <p>They facilitate coding of space and time (C)</p> Signup and view all the answers

    Which structure receives convergent input from both the lateral and medial entorhinal cortex?

    <p>Dentate gyrus (B)</p> Signup and view all the answers

    Which type of neurotransmitter action is associated with GABA?

    <p>Inhibits neuronal firing through chloride channels (D)</p> Signup and view all the answers

    What process links spatial context with specific events to form episodic memories?

    <p>Role of CA1 (A)</p> Signup and view all the answers

    What is meant by graded spiking in entorhinal cortex neurons?

    <p>Firing frequency adjusts based on the strength of input (A)</p> Signup and view all the answers

    Which ions are primarily involved in maintaining the resting potential of hippocampal neurons?

    <p>Sodium (Na⁺) and chloride (Cl⁻) (B)</p> Signup and view all the answers

    What is the primary role of the hippocampus in episodic memory formation?

    <p>Strengthening associations between sensory details and spatiotemporal trajectories (D)</p> Signup and view all the answers

    Which of the following best describes the function of the CA3 region in episodic memory?

    <p>Facilitating the categorization of memories by broader themes (C)</p> Signup and view all the answers

    What aspect of neuronal behavior is crucial for the support of episodic memory?

    <p>Spiking activity and synaptic potentials (A)</p> Signup and view all the answers

    Episodic memories can be triggered by which mechanism?

    <p>Convergence mechanisms (B)</p> Signup and view all the answers

    What is the primary purpose of the delayed spatial alternation task in rodents?

    <p>To assess memory retention across trial delays (B)</p> Signup and view all the answers

    Which brain structures are indicated to impair performance in delayed spatial alternation tasks when lesioned?

    <p>Hippocampus, septum, and fornix (B)</p> Signup and view all the answers

    What is the task involved in the Morris Water Maze designed to assess?

    <p>Learning and memory of platform location (A)</p> Signup and view all the answers

    How does the forced choice delayed alternation task differ from other alternation tasks?

    <p>The first choice is forced by blocking an arm (C)</p> Signup and view all the answers

    In the context of object investigation time, what aspect of memory is being assessed?

    <p>Memory of novel versus familiar stimuli (D)</p> Signup and view all the answers

    What happens to rat performance in the eight-arm radial maze when the hippocampus is lesioned?

    <p>They exhibit impairment in avoiding previously explored arms (D)</p> Signup and view all the answers

    What is demonstrated through probe trials in the Morris Water Maze?

    <p>Long-term retention of spatial memory (D)</p> Signup and view all the answers

    What best describes the role of the hippocampus in episodic memory?

    <p>It acts as a central hub for memory encoding and retrieval (A)</p> Signup and view all the answers

    What characterizes the spontaneous alternation task for rodents?

    <p>Rats follow their instinct to visit the unvisited arm from the last trial (A)</p> Signup and view all the answers

    What effect do fornix lesions have on rats in spatial reversal tasks?

    <p>Impairment of extinction after extensive training (B)</p> Signup and view all the answers

    Flashcards

    Episodic Memory

    Recollection of specific sensory experiences tied to times and places.

    Sensory Experiences

    Inputs from the senses that help create memories.

    Time in Episodic Memory

    Specific moments when events occur in episodic memory.

    Place in Episodic Memory

    Particular locations associated with memories.

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    Tulving's Definition

    Episodic memory defined by Endel Tulving in 1972.

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    Semantic Memory

    Memory for facts and general knowledge without specific context.

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    Procedural Memory

    Memory for skills and how to do things unconsciously.

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    Working Memory

    Short-term memory for holding and manipulating information.

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    Mental Time Travel

    The ability to mentally relive past experiences.

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    Spatiotemporal Trajectory

    Episodic memory as a sequence of spatial and timing information.

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    Key Components of Episodic Memory

    Includes absolute location, movement, direction, and timing.

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    HM Case Study

    A patient who lost the ability to form new episodic memories.

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    Anterograde Amnesia

    Inability to form new memories after a brain injury.

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    Retrograde Amnesia

    Loss of memories before a particular point in time.

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    Delayed Spatial Alternation

    A task where rats remember and alternate choices over a delay.

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    Rewarded Alternation Task

    A task where rats are rewarded for changing their choice from the previous trial.

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    Forced Choice Delayed Alternation

    A task where rats must choose the previously blocked arm after a delay.

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    Spatial Reversal

    Training rats to switch food locations on a T-maze after learning one side.

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    Eight-Arm Radial Maze

    A maze where rats navigate to find food while avoiding revisits.

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    Morris Water Maze

    A task to assess a rat's memory of a hidden platform using spatial cues.

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    Probe Trials

    Tests that measure how well rats recall a hidden platform's location after it's removed.

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    Object Investigation Time

    Evaluates memory by observing rats' focus on new versus familiar objects.

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    Hippocampal Lesions

    Damage to the hippocampus that impairs spatial learning and memory in rats.

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    Episodic Memory in Rats

    The capability of rats to remember details of what, where, and when regarding their experiences.

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    Parallel Streams

    Separate processing pathways for 'what' (items/events) and 'where' (spatial location) in the brain.

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    Lateral Entorhinal Cortex

    Processes items/events and receives input from the perirhinal cortex; projects to distal CA1.

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    Medial Entorhinal Cortex

    Processes spatial location; receives input from the parahippocampal cortex and relies on postsubiculum input.

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    Role of CA1

    Links spatial context ('where') with specific events ('what') to create episodic memories.

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    Reciprocal Richness

    Episodic memories integrate sensory details via widespread neuronal activation across sensory cortices.

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    Convergence Mechanism

    Episodic memories can be triggered by different contextual cues, integrating 'what' and 'where'.

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    Ion Concentration Dynamics

    Neurons maintain resting potential due to differences in sodium, chloride, and potassium ions, influencing excitability.

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    CA3 and Dentate Gyrus

    Receive convergent input from both lateral and medial entorhinal cortex, enabling memory differentiation by themes.

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    Hippocampal Damage Effects

    Hippocampal damage spares short-term memory but affects long-term retention.

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    Working Memory Capacity

    Hippocampus is needed when working memory capacity is exceeded, especially in longer lists.

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    Brown-Peterson Task

    A task that tests short-term memory decay in individuals, particularly amnesics.

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    Hippocampus and Memory

    Functional imaging studies tie hippocampal activity to memory encoding and retrieval.

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    Episodic-like Memory in Birds

    Scrub jays show episodic-like memory, recalling what, where, and when they stored food.

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    Primates and Episodic Memory

    Research on nonhuman primates links hippocampal studies to episodic memory in humans.

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    Impact of Lesions

    Lesions in various medial temporal structures have unique effects on memory performance.

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    Fornix in Memory Processing

    The fornix is involved in memory processing, especially linked to the hippocampus.

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    Action Potential

    A rapid spike in membrane potential when sodium channels open at ~-50mV.

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    Neurotransmitter Effects

    Glutamate excites, GABA inhibits, and acetylcholine modulates neural activity.

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    Persistent Spiking

    Neurons fire continuously after a stimulus ends, even with blocked transmission.

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    CAL Current

    Calcium-activated nonspecific cation current driving persistent spiking.

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    Oscillatory Activity

    Neurons resonate at specific frequencies, impacting spatial and temporal coding.

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    Theta-Frequency Oscillations

    Oscillations between 4-10 Hz in entorhinal and hippocampal circuits.

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    Spike Frequency Accommodation

    Gradual slowing of neuron firing during sustained input; forms short-term memory.

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    h-Current

    Hyperpolarization-activated cation current enabling rebound after inhibition.

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    Study Notes

    Chapter 1: Behavioral Dynamics of Episodic Memory

    • Definition: Episodic memory is the recollection of specific sensory experiences tied to particular times and places. It involves a sense of experiencing the event as if reliving it, represented as short time slices.
    • Contrast with other memory types:
      • Semantic Memory: General knowledge and facts, doesn't involve specific experiences or time/place.
      • Procedural Memory: Knowing how to perform tasks, often motor skills. Doesn't rely on conscious recollection of time-specific experiences.
      • Working Memory: Actively holds and manipulates information in the short term, not tied to past experiences.
    • Comparison to Mental Time Travel: Episodic memory involves mentally reliving past events.
    • Episodic Memory as a Spatiotemporal Trajectory: Episodic memory involves encoding and retrieving experiences as a continuous sequence of spatial and temporal information.
      • Key Components:
        • Absolute location: Specific places visited.
        • Movement and direction: The trajectory captured.
        • Timing: Relating events to time, including duration at each location.

    Chapter 2: Neural Dynamics of Episodic Memory

    • Anatomical Circuits:
      • Hippocampus: Central hub for encoding and retrieving episodic memories. Crucial for spatial and contextual memory.
      • Medial Temporal Lobe (MTL): Includes entorhinal, perirhinal, and parahippocampal cortices. Processes and relays episodic information to the hippocampus.
      • Fornix: Major white matter pathway connecting hippocampus to mammillary bodies and anterior thalamus, supporting memory consolidation.
      • Mammillary Bodies & Anterior Thalamus: Involved in relaying hippocampal outputs and integrating memory with executive and attentional processes.
      • Prefrontal Cortex: Regulates memory retrieval, organization, and decision-making related to episodic recall.
    • Principles of Connectivity:
      • Consistent Scales of Space and Time: Hierarchical spatial coding across different scales (e.g., room to object). Maintains consistent spatiotemporal maps for accurate retrieval.
      • Topographic Organization: Dorsal and ventral entorhinal cortex projects to dorsal and ventral hippocampus, respectively, creating a structured flow of spatial-temporal information.

    Network Oscillations

    • Theta Rhythm Oscillations: 4-10 Hz oscillations in hippocampus and entorhinal cortex, correlate with movement, arousal, and attention. Stronger theta power enhances learning. Theta frequency modulates with speed (velocity coding).
    • Gamma and Beta Rhythm Oscillations: Higher frequencies than theta, prominent in the neocortex during arousal and attention. Desynchronization (reduction in large-amplitude slow waves) indicates active cognitive processing. Theta-nested gamma: Gamma oscillations align with theta phases, supporting hippocampal interactions.

    Cellular Mechanisms and Episodic Memory

    • Neuronal Properties: Spiking activity, synaptic potentials and oscillatory dynamics support episodic memory in hippocampus and entorhinal cortex. Neurons maintain a resting potential, changes in ion conductance drive depolarization or hyperpolarization.
    • Action Potentials: Neurons triggers rapid spike-followed by potassium efflux to restore resting potential.
    • Glutamate & GABA: Glutamate excites neurons, while GABA inhibits. Acetylcholine modulates spiking and synaptic plasticity.
    • Persistent Spiking: Neurons continue firing after a stimulus ends, even when synaptic transmission is blocked. Driven by calcium-activated non-specific cation (CAN) current maintaining depolarization.
    • Membrane Potential Oscillations and Resonance: Neurons in entorhinal cortex resonate at specific frequencies, contributing to coding space and time.

    Spiking Patterns

    • Place Cells: Neurons in the hippocampus that fire selectively when an animal is in a specific spatial location, independent of rewards or specific tasks. Maintain consistent firing locations in consistent environments, but remap in new environments or when task conditions change. They exhibit directional selectivity.
    • Context-Dependent Firing/Memory Space Theory: Hippocampal neurons encode a multi-dimensional "memory space", integrating spatial and contextual information across an episode.
    • Splitter Cells: Hippocampal neurons differentiate firing based on past or future trajectories.
    • Oscillatory Interference Model of Grid Cells: Oscillatory interference model predicts multiple firing fields. Grid cell spacing increases along the dorsal-ventral axis due to a decrease in intrinsic oscillation frequency.

    Other Key Features

    • Theta Phase Precession: Hippocampal place cells fire at progressively earlier theta phases as an animal moves.
    • Grid Cells: Neurons in the medial entorhinal cortex that fire at multiple locations arranged in a hexagonal grid pattern. Provide a spatial coordinate system.
    • Head Direction Cells: Neurons that fire when an animal's head is oriented in a specific direction.
    • Adaptive Spatial Coding: Grid and place cells adjust their firing patterns in response to environmental changes.
    • Episodic Replay: Hippocampal neurons replay sequences of past experiences.

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    Description

    Explore the fascinating world of episodic memory in this quiz based on Chapter 1. Understand how episodic memory differs from semantic, procedural, and working memory, and learn about its characteristics and significance in cognitive psychology. Test your knowledge about the spatiotemporal aspects of this type of memory.

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