Psoriasis Causes and Triggers

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What is thought to cause the over activation of CD8+-T cells in psoriasis in HIV-positive individuals?

Diminished CD4+-T cell presence

Name one microbe that can worsen psoriasis.

Staphylococcus aureus

What is the characteristic feature of psoriasis in terms of the growth of the epidermal layer?

Abnormally excessive and rapid growth

Which medications can induce psoriasis?

Beta blockers, lithium, antimalarial medications, non steroidal antiinflammatory drugs Signup and view all the answers

How often are skin cells replaced in psoriasis compared to the usual replacement rate?

Every 3-5 days (usual rate: 28-30 days) Signup and view all the answers

What is the first phase in the sequence of pathological events in psoriasis?

Initiation phase Signup and view all the answers

What immune cells are involved in the inflammatory cascade that stimulates premature maturation of Keratinocytes in psoriasis?

Dendritic cells, macrophages, and T cells Signup and view all the answers

Which inflammatory signals secreted by immune cells are believed to stimulate keratinocytes to proliferate in psoriasis?

Interleukin γ, tumor necrosis factor-α, Interleukin1β, Interleukin-6, and Interleukin-22 Signup and view all the answers

What type of skin characteristics are typical for psoriasis?

Scaly, erythematous plaques, papules, or patches of skin Signup and view all the answers

How are gene mutations related to the development of psoriasis?

Gene mutations of proteins involved in the skin's barrier function are markers of susceptibility Signup and view all the answers

What diagnostic procedure involves examining skin cells under a microscope to determine if psoriasis is the cause of symptoms?

Skin biopsy Signup and view all the answers

What type of biopsy is usually performed by dermatologists to diagnose psoriasis?

Punch biopsy Signup and view all the answers

What is the autoimmune disease characterized by raised areas of abnormal skin that can vary in severity from small patches to complete body coverage?

Psoriasis Signup and view all the answers

What phenomenon is known as the triggering of psoriatic skin changes at a spot due to injury to the skin?

The Koebner phenomenon Signup and view all the answers

What is one of the causes of psoriasis where around one-third of people with psoriasis report a family history of the disease?

Genetics Signup and view all the answers

Name a lifestyle factor reported to worsen psoriasis that includes chronic infections, stress, and changes in season and climate.

Life style Signup and view all the answers

In individuals infected with HIV, what type of immune response characterizes the immune system compared to those with psoriasis?

Th2 subset of CD4+ helper T cells Signup and view all the answers

What is the pattern of cellular signals typical of the immune response in psoriasis vulgaris?

Th1 subset of CD4+ helper T cells and Th17 helper T cells Signup and view all the answers

Psoriasis Causes and Triggers

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Questions and Answers

What is thought to cause the over activation of CD8+-T cells in psoriasis in HIV-positive individuals?

Name one microbe that can worsen psoriasis.

What is the characteristic feature of psoriasis in terms of the growth of the epidermal layer?

Which medications can induce psoriasis?

How often are skin cells replaced in psoriasis compared to the usual replacement rate?

What is the first phase in the sequence of pathological events in psoriasis?

What immune cells are involved in the inflammatory cascade that stimulates premature maturation of Keratinocytes in psoriasis?

Which inflammatory signals secreted by immune cells are believed to stimulate keratinocytes to proliferate in psoriasis?

What type of skin characteristics are typical for psoriasis?

How are gene mutations related to the development of psoriasis?

What diagnostic procedure involves examining skin cells under a microscope to determine if psoriasis is the cause of symptoms?

What type of biopsy is usually performed by dermatologists to diagnose psoriasis?

What is the autoimmune disease characterized by raised areas of abnormal skin that can vary in severity from small patches to complete body coverage?

What phenomenon is known as the triggering of psoriatic skin changes at a spot due to injury to the skin?

What is one of the causes of psoriasis where around one-third of people with psoriasis report a family history of the disease?

Name a lifestyle factor reported to worsen psoriasis that includes chronic infections, stress, and changes in season and climate.

In individuals infected with HIV, what type of immune response characterizes the immune system compared to those with psoriasis?

What is the pattern of cellular signals typical of the immune response in psoriasis vulgaris?

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