Podcast
Questions and Answers
What is the function of proto-oncogenes?
What is the function of proto-oncogenes?
- Cause abnormal protein expression
- Inhibit apoptosis
- Suppress cell differentiation
- Promote cell growth and division (correct)
How do proto-oncogenes transform into oncogenes?
How do proto-oncogenes transform into oncogenes?
- By decreasing the production of corresponding proteins
- Through structural mutations and abnormal expression (correct)
- By triggering apoptosis
- By reducing cell proliferation
What can result from changes in the DNA sequence of an oncogene?
What can result from changes in the DNA sequence of an oncogene?
- Production of hyperactive or overexpressed protein (correct)
- Inhibition of protein production
- Enhanced apoptosis
- Suppression of cell growth
Which signaling pathway involves the activation of the Ras protein?
Which signaling pathway involves the activation of the Ras protein?
What is responsible for the transforming activity of the rasH oncogene detected in bladder carcinoma DNA?
What is responsible for the transforming activity of the rasH oncogene detected in bladder carcinoma DNA?
What is the main effect of activated ERK translocating to the nucleus?
What is the main effect of activated ERK translocating to the nucleus?
How can oncogenes be activated via chromosomal translocations?
How can oncogenes be activated via chromosomal translocations?
Which gene is translocated to form Bcr/Abl in chronic myeloid leukemia?
Which gene is translocated to form Bcr/Abl in chronic myeloid leukemia?
What is the main consequence of viral integration into the host cell's DNA?
What is the main consequence of viral integration into the host cell's DNA?
What is the main function of Imatinib in relation to mutated leukemic cells?
What is the main function of Imatinib in relation to mutated leukemic cells?
What is the main function of proto-oncogenes?
What is the main function of proto-oncogenes?
How do proto-oncogenes differ from oncogenes?
How do proto-oncogenes differ from oncogenes?
Which gene translocation forms Bcr/Abl in chronic myeloid leukemia?
Which gene translocation forms Bcr/Abl in chronic myeloid leukemia?
What is responsible for the transforming activity of the rasH oncogene detected in bladder carcinoma DNA?
What is responsible for the transforming activity of the rasH oncogene detected in bladder carcinoma DNA?
What is the initial step in MAP kinase signaling from growth factor receptors?
What is the initial step in MAP kinase signaling from growth factor receptors?
What is the main consequence of activated ERK translocating to the nucleus?
What is the main consequence of activated ERK translocating to the nucleus?
How are proto-oncogenes commonly activated to oncogenes?
How are proto-oncogenes commonly activated to oncogenes?
What is the main function of Imatinib in relation to mutated leukemic cells?
What is the main function of Imatinib in relation to mutated leukemic cells?
What is responsible for the transforming activity of the rasH oncogene detected in bladder carcinoma DNA?
What is responsible for the transforming activity of the rasH oncogene detected in bladder carcinoma DNA?
What can result from changes in the DNA sequence of an oncogene?
What can result from changes in the DNA sequence of an oncogene?
