Protein Targeting and Mannose Oligosaccharides
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Questions and Answers

Which organelle is involved in hydrolysis and contains a variety of degradative hydrolytic enzymes?

  • Lysosomes (correct)
  • Endoplasmic reticulum
  • Mitochondria
  • Golgi apparatus

    • What type of glycoproteins are most of the hydrolytic enzymes in lysosomes?

  • N-linked glycoproteins (correct)
  • Glycosylphosphatidylinositol (GPI)-anchored glycoproteins
  • Mannose 6-phosphate glycoproteins
  • O-linked glycoproteins

    • How are the enzymes destined for the lysosomes 'sorted' in the Golgi apparatus?

  • Through endocytosis
  • By attaching a phosphate group to mannose residues
  • By binding to mannose 6-phosphate receptors (correct)
  • By forming O-linked glycoproteins

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