Protein Structure Exam

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Questions and Answers

What is the consequence of the glutamic acid being replaced by valine in sickle-cell anemia?

  • Impaired oxygen binding to red blood cells (correct)
  • Increased circulation in small blood vessels
  • Enhanced oxygen binding to red blood cells
  • Prevention of organ damage

What type of bond stabilizes the α-helix structure in proteins?

  • Ionic bonds
  • Covalent bonds
  • Van der Waals forces
  • Hydrogen bonds (correct)

How are the hydrogen bonds arranged in the β-pleated sheet structure?

  • Distributed randomly along the peptide backbone
  • Only within a single polypeptide chain
  • Between all amino acid residues
  • Formed between different peptide chains (correct)

What is the role of the amide proton and carbonyl oxygen in forming secondary structures?

<p>Forming hydrogen bonds (D)</p> Signup and view all the answers

In the α-helix structure, where does the partial negative charge occur?

<p>C-terminus (C)</p> Signup and view all the answers

How do antiparallel β-pleated sheets differ from parallel sheets in terms of hydrophobic side chains distribution?

<p>Parallel sheets distribute hydrophobic side chains on both sides (A)</p> Signup and view all the answers

What is the primary structure of a protein defined by?

<p>The arrangement of amino acids in the protein (D)</p> Signup and view all the answers

Which terminus of a polypeptide chain contains the free carboxyl group?

<p>C-terminus (C)</p> Signup and view all the answers

What defines the one-dimensional first step in specifying the three-dimensional structure of a protein?

<p>Primary structure (C)</p> Signup and view all the answers

Which level of protein structure involves the arrangement of multiple polypeptide chains to form a functional protein complex?

<p>Quaternary structure (C)</p> Signup and view all the answers

What provides insight into the functional diversity of protein molecules in biological systems?

<p>Sequence variation within polypeptide chains (C)</p> Signup and view all the answers

Where is the amino sequence read from in a polypeptide chain?

<p>N-terminal end (C)</p> Signup and view all the answers

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