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Protein Structure Exam

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Questions and Answers

What is the consequence of the glutamic acid being replaced by valine in sickle-cell anemia?

Impaired oxygen binding to red blood cells (correct)

Increased circulation in small blood vessels

Enhanced oxygen binding to red blood cells

Prevention of organ damage

What type of bond stabilizes the α-helix structure in proteins?

Ionic bonds

Covalent bonds

Van der Waals forces

Hydrogen bonds (correct)

How are the hydrogen bonds arranged in the β-pleated sheet structure?

Distributed randomly along the peptide backbone

Only within a single polypeptide chain

Between all amino acid residues

Formed between different peptide chains (correct)

What is the role of the amide proton and carbonyl oxygen in forming secondary structures?

Forming hydrogen bonds Signup and view all the answers

In the α-helix structure, where does the partial negative charge occur?

C-terminus Signup and view all the answers

How do antiparallel β-pleated sheets differ from parallel sheets in terms of hydrophobic side chains distribution?

Parallel sheets distribute hydrophobic side chains on both sides Signup and view all the answers

What is the primary structure of a protein defined by?

The arrangement of amino acids in the protein Signup and view all the answers

Which terminus of a polypeptide chain contains the free carboxyl group?

C-terminus Signup and view all the answers

What defines the one-dimensional first step in specifying the three-dimensional structure of a protein?

Primary structure Signup and view all the answers

Which level of protein structure involves the arrangement of multiple polypeptide chains to form a functional protein complex?

Quaternary structure Signup and view all the answers

What provides insight into the functional diversity of protein molecules in biological systems?

Sequence variation within polypeptide chains Signup and view all the answers

Where is the amino sequence read from in a polypeptide chain?

N-terminal end Signup and view all the answers