Podcast
Questions and Answers
Which of the following is a definition of a ligand?
Which of the following is a definition of a ligand?
- A molecule that interacts with macromolecules such as protein, DNA or adipose
- A molecule that is responsible for complex formation of drug with protein
- A molecule that is metabolized and excreted
- A molecule that irreversibly binds to a receiving protein molecule (correct)
What is the term used to describe the complex formation of a drug with protein?
What is the term used to describe the complex formation of a drug with protein?
- Determination of protein-drug binding
- Kinetics of protein drug binding
- Protein binding of drug (correct)
- Classes of protein drug binding
Why is a protein bound drug not metabolized or excreted?
Why is a protein bound drug not metabolized or excreted?
- Because it is a ligand
- Because it is bound to a protein (correct)
- Because it interacts with macromolecules such as protein, DNA or adipose
- Because it irreversibly binds to a receiving protein molecule
What are the tissue components available in the body for biological interactions to take place?
What are the tissue components available in the body for biological interactions to take place?
What are the factors that can affect protein drug binding?
What are the factors that can affect protein drug binding?