Protein Binding of Drugs
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Questions and Answers

Which of the following is a definition of a ligand?

  • A molecule that interacts with macromolecules such as protein, DNA or adipose
  • A molecule that is responsible for complex formation of drug with protein
  • A molecule that is metabolized and excreted
  • A molecule that irreversibly binds to a receiving protein molecule (correct)
  • What is the term used to describe the complex formation of a drug with protein?

  • Determination of protein-drug binding
  • Kinetics of protein drug binding
  • Protein binding of drug (correct)
  • Classes of protein drug binding
  • Why is a protein bound drug not metabolized or excreted?

  • Because it is a ligand
  • Because it is bound to a protein (correct)
  • Because it interacts with macromolecules such as protein, DNA or adipose
  • Because it irreversibly binds to a receiving protein molecule
  • What are the tissue components available in the body for biological interactions to take place?

    <p>Blood and extravascular tissues</p> Signup and view all the answers

    What are the factors that can affect protein drug binding?

    <p>Other relevant factors</p> Signup and view all the answers

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