Protein Binding of Drugs

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Questions and Answers

Which of the following is true about protein binding of drugs?

  • Protein binding of drugs occurs when a drug is metabolized or excreted.
  • Protein binding of drugs occurs when a drug binds to DNA.
  • Protein binding of drugs occurs when a drug binds to blood cells.
  • Protein binding of drugs occurs when a drug irreversibly binds to a receptor protein. (correct)

What is a ligand in the context of protein binding of drugs?

  • A ligand is a drug that is metabolized or excreted.
  • A ligand is a molecule or atom that irreversibly binds to a receptor protein. (correct)
  • A ligand is a drug that binds to blood cells.
  • A ligand is a protein responsible for drug-protein interactions.

What is the significance of protein/tissue binding of drugs?

  • Protein/tissue binding of drugs is irrelevant to drug action.
  • Protein/tissue binding of drugs enhances drug metabolism and excretion.
  • Protein/tissue binding of drugs increases drug toxicity.
  • Protein/tissue binding of drugs prevents drug metabolism and excretion. (correct)

What are the factors that can affect protein drug binding?

<p>pH, temperature, and drug concentration (C)</p> Signup and view all the answers

What is the definition of a protein bound drug?

<p>A protein bound drug is a drug that is neither metabolized nor excreted. (B)</p> Signup and view all the answers

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