Prostate Cancer and Benign Prostatic Hyperplasia Quiz

Play an AI-generated podcast conversation about this lesson

What is the most common non-cutaneous cancer in men?

Colorectal Cancer

Melanoma

Adenocarcinoma of Prostate (correct)

Lung Cancer

What is produced by prostate epithelial cells?

Dihydrotestosterone

Prostate Specific Antigen (PSA) (correct)

Estrogen

Testosterone

What is the normal PSA level?

< 2ng/mL

< 8ng/mL

< 4ng/mL (correct)

< 6ng/mL

What is the main hormone responsible for Benign Prostatic Hyperplasia?

Dihydrotestosterone Signup and view all the answers

What is the role of Type II 5-a-reductase in Prostatic Nodular Hyperplasia?

Converting testosterone to dihydrotestosterone Signup and view all the answers

What is the consequence of chronic bladder obstruction in Prostatic Nodular Hyperplasia?

All of the above Signup and view all the answers

What is the origin of Adenocarcinoma of Prostate?

Luminal cells Signup and view all the answers

What is the role of Estrogen in Prostatic Nodular Hyperplasia?

Increases the production of androgen receptors Signup and view all the answers

What is the result of DHT stimulation in Prostatic Nodular Hyperplasia?

Stimulates stromal and epithelial cell proliferation Signup and view all the answers

What is a genetic factor that increases the risk of prostate cancer?

All of the above Signup and view all the answers

What is the role of androgen and androgen receptor signaling in adenocarcinoma?

It is critical in the pathogenesis of adenocarcinoma Signup and view all the answers

What is the characteristic of the tumor cells in adenocarcinoma?

They overexpress alpha methylacyl-CoA racemase (AMACR) Signup and view all the answers

What is the significance of an elevated PSA level?

It is a screening test for prostate cancer Signup and view all the answers

What is the Gleason score based on?

The histologic pattern of the tumor Signup and view all the answers

What is the characteristic of a Gleason score of 1?

Very rare, single, separate, closely packed, uniform round glands in a circumscribed nodule with pushing borders Signup and view all the answers

What is the significance of an abnormal digital rectal examination?

It is a nonspecific symptom of adenocarcinoma Signup and view all the answers

What is the role of HK2 in adenocarcinoma?

It is a human kallikrein-2 Signup and view all the answers

What is the characteristic of the tumor cells in adenocarcinoma in terms of basal cells?

They are absent in cancer Signup and view all the answers