Prostate Cancer and Benign Prostatic Hyperplasia Quiz
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Questions and Answers

What is the most common non-cutaneous cancer in men?

  • Colorectal Cancer
  • Melanoma
  • Adenocarcinoma of Prostate (correct)
  • Lung Cancer
  • What is produced by prostate epithelial cells?

  • Dihydrotestosterone
  • Prostate Specific Antigen (PSA) (correct)
  • Estrogen
  • Testosterone
  • What is the normal PSA level?

  • < 2ng/mL
  • < 8ng/mL
  • < 4ng/mL (correct)
  • < 6ng/mL
  • What is the main hormone responsible for Benign Prostatic Hyperplasia?

    <p>Dihydrotestosterone</p> Signup and view all the answers

    What is the role of Type II 5-a-reductase in Prostatic Nodular Hyperplasia?

    <p>Converting testosterone to dihydrotestosterone</p> Signup and view all the answers

    What is the consequence of chronic bladder obstruction in Prostatic Nodular Hyperplasia?

    <p>All of the above</p> Signup and view all the answers

    What is the origin of Adenocarcinoma of Prostate?

    <p>Luminal cells</p> Signup and view all the answers

    What is the role of Estrogen in Prostatic Nodular Hyperplasia?

    <p>Increases the production of androgen receptors</p> Signup and view all the answers

    What is the result of DHT stimulation in Prostatic Nodular Hyperplasia?

    <p>Stimulates stromal and epithelial cell proliferation</p> Signup and view all the answers

    What is a genetic factor that increases the risk of prostate cancer?

    <p>All of the above</p> Signup and view all the answers

    What is the role of androgen and androgen receptor signaling in adenocarcinoma?

    <p>It is critical in the pathogenesis of adenocarcinoma</p> Signup and view all the answers

    What is the characteristic of the tumor cells in adenocarcinoma?

    <p>They overexpress alpha methylacyl-CoA racemase (AMACR)</p> Signup and view all the answers

    What is the significance of an elevated PSA level?

    <p>It is a screening test for prostate cancer</p> Signup and view all the answers

    What is the Gleason score based on?

    <p>The histologic pattern of the tumor</p> Signup and view all the answers

    What is the characteristic of a Gleason score of 1?

    <p>Very rare, single, separate, closely packed, uniform round glands in a circumscribed nodule with pushing borders</p> Signup and view all the answers

    What is the significance of an abnormal digital rectal examination?

    <p>It is a nonspecific symptom of adenocarcinoma</p> Signup and view all the answers

    What is the role of HK2 in adenocarcinoma?

    <p>It is a human kallikrein-2</p> Signup and view all the answers

    What is the characteristic of the tumor cells in adenocarcinoma in terms of basal cells?

    <p>They are absent in cancer</p> Signup and view all the answers

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