Propofol vs

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Which drug induces hypnosis or sleep?

Soybean oil

Methohexital

Thiopental

Propofol (correct)

What is the main advantage of propofol as an anesthetic?

It causes increased plasma triglycerides concentrations

It induces unconsciousness within 30 seconds (correct)

It supports bacterial growth

It is an insoluble drug

What is the purpose of soybean oil in the formulation of propofol?

To emulsify the drug (correct)

To induce hypnosis

To reduce anxiety

To support bacterial growth

Which organ is responsible for the rapid and extensive metabolism of propofol?

Liver (B) Signup and view all the answers

What is the major metabolic pathway for propofol?

Glucuronidation (C) Signup and view all the answers

What is the elimination half-time of propofol?

40 to 60 minutes (B) Signup and view all the answers

Which patient population exhibits a decreased rate of plasma clearance of propofol?

Patients older than 60 years of age (D) Signup and view all the answers

Which drug has replaced thiopental for induction of anesthesia in many clinical situations?

Propofol (B) Signup and view all the answers

What is the typical conscious sedation dose of propofol for IV sedation?

75 to 100 mg/kg/minute (A) Signup and view all the answers

Which drug may be added to propofol for continuous IV sedation in selected patients?

Midazolam (D) Signup and view all the answers

Which drug has emerged as the agent of choice for sedation during brief gastrointestinal endoscopy procedures?

Propofol (A) Signup and view all the answers

Which effect of propofol is related to its ability to depress spinal cord activity?

Antipruritic effect (D) Signup and view all the answers

Propofol possesses antiepileptic properties due to its inhibition of which ion channels?

Chloride ion channels (C) Signup and view all the answers

Which formulation of propofol may cause bronchoconstriction in asthmatic patients?

Propofol with metabisulfite (C) Signup and view all the answers

What effect does propofol have on cerebral blood flow and intracranial pressure?

Decreases cerebral blood flow and intracranial pressure (A) Signup and view all the answers

Which of the following is true about the impact of propofol on sympathetic nervous system activation?

Propofol blunts the increase in epinephrine concentration associated with a sudden increase in desflurane concentration. (D) Signup and view all the answers

Which patients may experience exaggerated blood pressure effects from propofol?

All of the above (D) Signup and view all the answers

What is the effect of propofol on heart rate?

Propofol has no effect on heart rate. (B) Signup and view all the answers

What is the risk of bradycardia-related death during propofol anesthesia?

1 in 100,000 (D) Signup and view all the answers

Which of the following drugs is frequently added to propofol in attempts to prevent pain with IV injection?

Lidocaine (C) Signup and view all the answers

Which of the following is NOT a difference between Diprivan and generic propofol?

Method of administration (A) Signup and view all the answers

Which of the following is a characteristic of Ampofol, a low-lipid emulsion of propofol?

Contains 5% soybean oil and 0.6% egg lecithin (D) Signup and view all the answers

What is the mechanism of action of propofol?

Selective modulation of GABA A receptors (A) Signup and view all the answers

Which of the following is NOT true about propofol's effect on intraocular pressure?

Propofol increases intraocular pressure during laparoscopic surgery. (A) Signup and view all the answers

Which of the following is NOT true about propofol's effect on coagulation?

Propofol alters tests of coagulation and platelet function. (D) Signup and view all the answers

Which of the following is NOT true about cloudy urine caused by propofol?

Cloudy urine caused by propofol is considered to be detrimental to renal function. (D) Signup and view all the answers