11 Questions
What criteria must be met for primary prophylaxis to be administered to inpatients with cirrhosis?
Renal dysfunction and ascitic fluid protein >1.5 g/dL
Who is recommended to receive secondary prophylaxis for spontaneous bacterial peritonitis (SBP)?
Patients who have had an episode of SBP
Which antibiotic is recommended for primary prophylaxis in patients with cirrhosis at risk for SBP?
Ciprofloxacin 750mg PO qweekly
What duration is recommended for secondary prophylaxis of SBP in patients?
Forever, unless liver transplant or full resolution of ascites
Why is daily dosing of antibiotics preferred over intermittent dosing for SBP prophylaxis?
Daily dosing is more effective in preventing resistant flora
What is the most common etiology of Spontaneous Bacterial Peritonitis in cirrhosis patients?
Bacterial translocation from intestinal lumen
What is a key indicator for diagnosing Spontaneous Bacterial Peritonitis through diagnostic paracentesis?
Presence of >250 white blood cells per milliliter in ascitic fluid
Which of the following clinical manifestations is NOT commonly associated with Spontaneous Bacterial Peritonitis?
Hypertension
What is the recommended empiric antibiotic treatment for Spontaneous Bacterial Peritonitis if there is a risk of Multi-Drug Resistant Organisms (MDROs)?
Piperacillin/tazobactam or meropenem
What is the primary pharmacologic management strategy for Spontaneous Bacterial Peritonitis?
Antibiotic therapy
What is the recommended duration of antibiotic treatment for Spontaneous Bacterial Peritonitis?
5-7 days
Test your knowledge on primary and secondary prophylaxis in inpatients with cirrhosis who are at risk for developing spontaneous bacterial peritonitis (SBP). Learn about the indications for primary prophylaxis based on complications like gastrointestinal bleed, low ascitic fluid protein, renal dysfunction, and liver failure, as well as the criteria for secondary prophylaxis.
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