Prophylaxis in Patients with Cirrhosis Quiz

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Questions and Answers

What criteria must be met for primary prophylaxis to be administered to inpatients with cirrhosis?

  • Renal dysfunction and ascitic fluid protein <1.5 g/dL
  • Renal dysfunction and ascitic fluid protein >1.5 g/dL (correct)
  • Ascitic fluid protein <1.5 g/dL and liver failure with Child Pugh score >9
  • Gastrointestinal bleed and ascitic fluid protein >1.5 g/dL

Who is recommended to receive secondary prophylaxis for spontaneous bacterial peritonitis (SBP)?

  • Patients who have never had SBP before
  • Patients who have had an episode of SBP (correct)
  • Patients with liver failure and ascites
  • Patients without any complications

Which antibiotic is recommended for primary prophylaxis in patients with cirrhosis at risk for SBP?

  • Amoxicillin 500mg PO daily
  • Ciprofloxacin 750mg PO qweekly (correct)
  • Rifaximin 1200mg PO daily
  • SMX/TMP 1 DS tab PO 5x/week

What duration is recommended for secondary prophylaxis of SBP in patients?

<p>Forever, unless liver transplant or full resolution of ascites (A)</p> Signup and view all the answers

Why is daily dosing of antibiotics preferred over intermittent dosing for SBP prophylaxis?

<p>Daily dosing is more effective in preventing resistant flora (A)</p> Signup and view all the answers

What is the most common etiology of Spontaneous Bacterial Peritonitis in cirrhosis patients?

<p>Bacterial translocation from intestinal lumen (C)</p> Signup and view all the answers

What is a key indicator for diagnosing Spontaneous Bacterial Peritonitis through diagnostic paracentesis?

<p>Presence of &gt;250 white blood cells per milliliter in ascitic fluid (B)</p> Signup and view all the answers

Which of the following clinical manifestations is NOT commonly associated with Spontaneous Bacterial Peritonitis?

<p>Hypertension (A)</p> Signup and view all the answers

What is the recommended empiric antibiotic treatment for Spontaneous Bacterial Peritonitis if there is a risk of Multi-Drug Resistant Organisms (MDROs)?

<p>Piperacillin/tazobactam or meropenem (B)</p> Signup and view all the answers

What is the primary pharmacologic management strategy for Spontaneous Bacterial Peritonitis?

<p>Antibiotic therapy (A)</p> Signup and view all the answers

What is the recommended duration of antibiotic treatment for Spontaneous Bacterial Peritonitis?

<p>5-7 days (B)</p> Signup and view all the answers

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