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Prophylaxis in Patients with Cirrhosis Quiz

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Prophylaxis in Patients with Cirrhosis Quiz

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Questions and Answers

What criteria must be met for primary prophylaxis to be administered to inpatients with cirrhosis?

Renal dysfunction and ascitic fluid protein <1.5 g/dL

Renal dysfunction and ascitic fluid protein >1.5 g/dL (correct)

Ascitic fluid protein <1.5 g/dL and liver failure with Child Pugh score >9

Gastrointestinal bleed and ascitic fluid protein >1.5 g/dL

Who is recommended to receive secondary prophylaxis for spontaneous bacterial peritonitis (SBP)?

Patients who have never had SBP before

Patients who have had an episode of SBP (correct)

Patients with liver failure and ascites

Patients without any complications

Which antibiotic is recommended for primary prophylaxis in patients with cirrhosis at risk for SBP?

Amoxicillin 500mg PO daily

Ciprofloxacin 750mg PO qweekly (correct)

Rifaximin 1200mg PO daily

SMX/TMP 1 DS tab PO 5x/week

What duration is recommended for secondary prophylaxis of SBP in patients?

Forever, unless liver transplant or full resolution of ascites Signup and view all the answers

Why is daily dosing of antibiotics preferred over intermittent dosing for SBP prophylaxis?

Daily dosing is more effective in preventing resistant flora Signup and view all the answers

What is the most common etiology of Spontaneous Bacterial Peritonitis in cirrhosis patients?

Bacterial translocation from intestinal lumen Signup and view all the answers

What is a key indicator for diagnosing Spontaneous Bacterial Peritonitis through diagnostic paracentesis?

Presence of >250 white blood cells per milliliter in ascitic fluid Signup and view all the answers

Which of the following clinical manifestations is NOT commonly associated with Spontaneous Bacterial Peritonitis?

Hypertension Signup and view all the answers

What is the recommended empiric antibiotic treatment for Spontaneous Bacterial Peritonitis if there is a risk of Multi-Drug Resistant Organisms (MDROs)?

Piperacillin/tazobactam or meropenem Signup and view all the answers

What is the primary pharmacologic management strategy for Spontaneous Bacterial Peritonitis?

Antibiotic therapy Signup and view all the answers

What is the recommended duration of antibiotic treatment for Spontaneous Bacterial Peritonitis?

5-7 days Signup and view all the answers