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Questions and Answers
What is cirrhosis?
What is cirrhosis?
- A mild, reversible disease affecting the liver cells
- A condition causing normal hepatocyte conversion into healthy nodules
- An acute disease leading to hepatocyte regeneration
- A severe, chronic, irreversible liver disease characterized by fibrosis of the hepatic parenchyma (correct)
What happens as a result of continued hepatocyte death in cirrhosis?
What happens as a result of continued hepatocyte death in cirrhosis?
- The hepatic parenchyma becomes unaffected
- The liver cells regenerate at an accelerated rate
- The fibrous scar tissue is replaced by healthy hepatocytes
- The number of normally functioning liver cells reduces further (correct)
What is the consequence of cirrhosis on the liver cells?
What is the consequence of cirrhosis on the liver cells?
- Conversion into structurally normal nodules
- Enhanced regeneration and multiplication of hepatocytes
- Destruction and replacement by fibrous scar tissue (correct)
- Decreased fibrosis in the hepatic parenchyma
What is the process that defines cirrhosis?
What is the process that defines cirrhosis?
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Study Notes
Understanding Cirrhosis
- Cirrhosis is a late-stage liver disease characterized by scarring (fibrosis) of the liver tissue.
- It results from chronic damage to the liver caused by factors such as alcohol abuse, viral hepatitis, and non-alcoholic fatty liver disease.
Consequences of Continued Hepatocyte Death
- Persistent death of hepatocytes (liver cells) leads to inflammation and necrosis, disrupting normal liver function.
- The continuous process results in compensatory hyperplasia, where the liver attempts to repair itself, increasing the risk of further cellular damage.
Impact on Liver Cells
- Cirrhosis leads to the replacement of healthy hepatocytes with fibrous tissue, impairing the liver's ability to perform essential metabolic processes.
- Structural changes in the liver architecture can alter blood flow and exacerbate liver dysfunction.
Defining Process of Cirrhosis
- The development of cirrhosis involves a progressive cycle of liver injury, inflammation, and regeneration followed by fibrosis.
- This process culminates in significant loss of liver function, resulting in complications such as portal hypertension and liver failure.
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