Properties of Solid System in Pharmaceutical Dosage Forms

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Questions and Answers

Which type of solid dosage form is the most important for pharmaceuticals?

  • Compressed products
  • Loose powdered drugs
  • Tablets and capsules (correct)
  • Powders and granules

What advantage do solid dosage forms have over liquid dosage forms?

  • They are more easily absorbed by the body
  • They do not require preservatives for microbial stability (correct)
  • They can be administered without medical supervision
  • They have a longer shelf life

Which factor is less problematic for solid dosage forms compared to liquid dosage forms?

  • Ease of administration
  • Absorption by the body
  • Microbial stability (correct)
  • Shelf life

What percentage of all medicines licensed are oral solid dosage forms?

<p>50% (D)</p> Signup and view all the answers

What type of administration do tablets and capsules offer the patient an advantage in?

<p>Ease and convenience of administration (D)</p> Signup and view all the answers

What is the most rare form of solid dosage form used these days?

<p>Powdered drugs (A)</p> Signup and view all the answers

What is the term 'particle size' a reflection of?

<p>Surface area and projected areas (D)</p> Signup and view all the answers

Which type of particle has a greater surface area per unit volume?

<p>Asymmetric particle (A)</p> Signup and view all the answers

What is the equivalent spherical diameter used for?

<p>To assign a meaningful diameter to asymmetric particles (A)</p> Signup and view all the answers

What is Stoke's diameter used to describe?

<p>An equivalent sphere undergoing sedimentation at the same rate as the asymmetric particle (D)</p> Signup and view all the answers

Which type of tablet dissolves in the mouth without water?

<p>Mouth dissolving tablet (B)</p> Signup and view all the answers

What is the purpose of an enteric coated tablet?

<p>To protect the drug from being broken down by stomach acid (B)</p> Signup and view all the answers

Flashcards

Most important solid dosage form

Tablets and capsules are the most common type of solid dosage form used in pharmaceuticals.

Advantage of solid dosage forms

Solid dosage forms, like tablets and capsules, don't need preservatives to prevent bacteria growth.

Less problematic for solids

Solid dosage forms are less susceptible to microbial contamination compared to liquid dosage forms.

Percentage of oral solids

Over half of all approved medicines are taken orally as solid dosage forms.

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Advantage of tablets and capsules

Tablets and capsules are easy and convenient for patients to take.

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Rarest solid dosage form

Powdered drugs are the least common type of solid dosage form used today.

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Particle size

Particle size is a measure of the surface area and projected areas of a solid particle.

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Surface area of asymmetric particles

Asymmetric particles have a larger surface area per unit volume than spherical particles.

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Equivalent spherical diameter

The equivalent spherical diameter is used to approximate the size of irregular particles as if they were spheres.

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Stoke's diameter

Stoke's diameter describes the size of an imaginary sphere that would settle at the same rate as an asymmetric particle.

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Mouth dissolving tablet

Mouth dissolving tablets, also known as orally disintegrating tablets, dissolve in the mouth without the need for water.

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Enteric coated tablet

Enteric coated tablets are designed to resist stomach acid and release the drug in the small intestine.

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