PCT 202: Properties of Solid Systems - Introduction and Particle Size

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Questions and Answers

What is the advantage of oral solid dosage forms over injectable dosage forms?

  • They offer quicker absorption
  • They require less qualified personnel for administration
  • They provide ease and convenience of administration (correct)
  • They are more cost-effective

Which method is not used for particle size determination in solid systems?

  • Sedimentation Analysis
  • X-Ray Diffraction (correct)
  • Laser Diffraction
  • Sieve Analysis

Which type of solid dosage form is known for offering microbial stability without the need for preservatives?

  • Tablets (correct)
  • Powders
  • Capsules
  • Granules

What is a common type of large dose oral powder dosage form?

<p>Dusting powder (B)</p> Signup and view all the answers

Which of the following is NOT a type of solid dosage form discussed in the text?

<p>Lozenges (D)</p> Signup and view all the answers

What is a key reason why powdered drugs are rarely used today?

<p>They lack microbial stability (A)</p> Signup and view all the answers

What type of tablets are designed to release their contents gradually over an extended period of time?

<p>Sustained-release tablets (C)</p> Signup and view all the answers

Which type of tablets are designed to dissolve quickly in the mouth without the need for water?

<p>Mouth dissolving tablets (C)</p> Signup and view all the answers

What is the property of a particle that makes it difficult to assign a meaningful diameter?

<p>Asymmetric shape (A)</p> Signup and view all the answers

Which method of determining particle size involves expressing the diameter in terms of weights, volumes, or surface areas?

<p>Surface area (C)</p> Signup and view all the answers

Which type of capsules are made from a flexible, gel-like material?

<p>Soft gelatin capsules (B)</p> Signup and view all the answers

What is the purpose of enteric-coated tablets?

<p>To resist disintegration in the stomach and dissolve in the intestines (D)</p> Signup and view all the answers

Why is it important to have a good knowledge and control of the particle size of a drug in pharmacy?

<p>To affect the rate of release of the drug from different dosage forms (D)</p> Signup and view all the answers

How does particle size influence the formulation of tablets and capsules?

<p>It is crucial for achieving proper flow properties and mixing of granules (C)</p> Signup and view all the answers

In what way can small particles in a suspension affect its usability?

<p>Small particles settle rapidly, making re-dispersion challenging (C)</p> Signup and view all the answers

What is the significance of particle size in mixtures of solids?

<p>Particle size affects the mixing of solid substances (B)</p> Signup and view all the answers

What are the two important properties in a polydisperse sample of particles?

<p>Shape and surface area of individual particles (B)</p> Signup and view all the answers

How does particle size affect the release of a drug from dosage forms?

<p>Optimal particle size can regulate the rate of drug release (C)</p> Signup and view all the answers

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