Prokinetic Agents in Gastrointestinal Health

<p>It was associated with cardiovascular safety concerns</p> Signup and view all the answers

<p>Antagonizing dopamine 2 receptors to enhance acetylcholine release</p> Signup and view all the answers

<p>Tegaserod was safe and consistently efficacious for chronic constipation, and its cardiovascular safety will be confirmed in larger studies</p> Signup and view all the answers

<p>It enhances cholinergic activity by acting at multiple sites, including directly or via dopamine2 receptor blockade</p> Signup and view all the answers

<p>It is more effective in promoting gastric emptying in healthy subjects than in patients receiving long-term anticholinergic therapy</p> Signup and view all the answers

<p>It is a medication used to treat constipation that has mild and transient side effects such as headache and diarrhea</p> Signup and view all the answers

<p>Concerns about its cardiovascular safety, as studies found it increased the risk of cardiovascular events</p> Signup and view all the answers

<p>It has been reported to consistently improve fecal incontinence in the elderly</p> Signup and view all the answers

<p>It may cause relaxation of the sphincter in some patients</p> Signup and view all the answers

<p>It was recommended for use in patients with irritable bowel syndrome-constipation (IBS-C)</p> Signup and view all the answers

<p>It is currently under close monitoring due to concerns about its potential to cause severe hepatic impairment</p> Signup and view all the answers

<p>It has been reported to worsen fecal incontinence and increase the likelihood of this side effect occurring in the elderly</p> Signup and view all the answers

<p>It has been shown to consistently increase the frequency of contractions and phasic activity of the colon</p> Signup and view all the answers