Podcast
Questions and Answers
What is the primary mechanism of action for prokinetic agents?
What is the primary mechanism of action for prokinetic agents?
- Stimulating dopamine 2 receptors to inhibit enteric neuron activity
- Enhancing the release of acetylcholine to increase smooth muscle contractility (correct)
- Antagonizing 5HT-4 receptors to reduce visceral hypersensitivity
- Inhibiting the release of acetylcholine to decrease smooth muscle contractility
Which of the following is NOT a common side effect associated with metoclopramide?
Which of the following is NOT a common side effect associated with metoclopramide?
- Increased gastrointestinal motility (correct)
- Fatigue
- Extrapyramidal effects
- Drowsiness
What is the primary advantage of domperidone over metoclopramide?
What is the primary advantage of domperidone over metoclopramide?
- Domperidone is a cheaper alternative to metoclopramide (correct)
- Domperidone has a lower incidence of side effects
- Domperidone acts centrally while metoclopramide acts peripherally
- Domperidone is a serotonin receptor agonist while metoclopramide is a dopamine receptor antagonist
Why was tegaserod withdrawn from the market in 2007?
Why was tegaserod withdrawn from the market in 2007?
What is the primary mechanism of action for metoclopramide?
What is the primary mechanism of action for metoclopramide?
What was the conclusion of the pooled analysis of 13 controlled studies on tegaserod?
What was the conclusion of the pooled analysis of 13 controlled studies on tegaserod?
What is the primary mechanism of action of metoclopramide?
What is the primary mechanism of action of metoclopramide?
Which of the following statements about metoclopramide is true?
Which of the following statements about metoclopramide is true?
Which of the following statements about prucalopride is accurate?
Which of the following statements about prucalopride is accurate?
What led to the withdrawal of tegaserod from use in 2007?
What led to the withdrawal of tegaserod from use in 2007?
Which of the following statements about cisapride is false?
Which of the following statements about cisapride is false?
Which of the following statements about metoclopramide is true?
Which of the following statements about metoclopramide is true?
Based on the information provided, which of the following statements about tegaserod is accurate?
Based on the information provided, which of the following statements about tegaserod is accurate?
Which of the following statements about prucalopride is true?
Which of the following statements about prucalopride is true?
Based on the information provided, which of the following statements about cisapride is accurate?
Based on the information provided, which of the following statements about cisapride is accurate?
According to the information provided, which of the following statements about metoclopramide is false?
According to the information provided, which of the following statements about metoclopramide is false?