Progestins

During which phase of the menstrual cycle does the dominant follicle produce estrogen?

What hormone provides negative feedback to the pituitary, inhibiting FSH release?

What hormone causes the endometrium to become thicker during the follicular phase?

Which hormone prompts ovulation?

Which structure in the female reproductive system thins and dilates during childbirth?

What is the function of the uterine tubes in the female reproductive system?

Where does oogenesis, the development of female gametes, occur in the female reproductive system?

What is the function of the corpus luteum in the female reproductive system?

Which compound is the primary estrogen used in oral contraceptives?

Which compound is 50% less potent than Ethinyl estradiol?

Which compound has a long half-life of 24-28 hours and is minimally metabolized?

Which compound has unsaturation (double bonds) in Ring B, which DECREASES estrogenic potency?

Which type of contraception method is known to prevent ovulation and thicken cervical mucus?

What is the primary mechanism of action for combination pills in preventing pregnancy?

Which type of contraception method is known to have a higher risk of thromboembolism?

Which of the following is a possible adverse effect of SERMs?

Which of the following is a characteristic of clomiphene?

Which of the following is a true statement about progestins?

Which of the following is a clinical use of progestins?

Which of the following is NOT a clinical use of estrogens?

Which of the following is a membrane ER effect?

Which receptor type stimulates breast growth and reduces the risk of breast cancer?

What do NEST drugs promote and prevent?

Which of the following is a nonhormonal contraceptive?

Which of the following is an adverse effect of Phexxi?

Which contraceptive method is CI (contraindicated) in patients with renal and/or hepatic impairment?

Which contraceptive method has a weight restriction of BMI >30?

Which contraceptive method is a transdermal patch?

During the ______ phase, the corpus luteum is secreting estrogen, progesterone, inhibin.

The pathway to estrogen production varies from ______ to luteal phase.

Estriol (E3) is a ______ estrogen and minor female sex hormone.

In the luteal phase, ______ is a precursor for estrogens.

Non-steroidal compounds with estrogenic activity include _______ and _______.

Estradiol is converted in the liver to _______ and _______.

Estrogen receptors form a complex of proteins and bind to _______ in promoter sequences.

Estrogen promotes the development and growth of the _______.

Progestins enter cells and bind to ______ receptors (cytoplasm and nucleus)

Adding a halogen at C6 or C7 ______ activity at the progesterone receptor

Removing the 3-keto group ______ activity at the progesterone receptor

Progestins are given to stimulate or maintain ______

During prenatal development, millions of primordial follicles are formed. These consist of single, large cell called an oocyte, which is surrounded by layer of ______ cells.

Around day 7 on the cycle, 1 follicle becomes dominant, and the others die through a process called ______.

Corpus Luteum – ruptured follicle after ovulation; very ______.

Each month, 3-30 follicles will begin maturation within the ovary. ______ is released into open space and drawn into tube by beating cilia.

Progestins are given during the ______ Phase to transform a proliferative uterine endometrium into a more differentiated, secretory one.

Progestins can be given ______ to prevent ovulation, increase viscosity of cervical mucus, decrease motility within uterine tubes, and create atrophic endometrium.

The combination pills of hormonal contraception contain both estrogens and ______.

The progesterone antagonist, Mifeprestone (RU-486), can terminate pregnancies in the first 7 weeks in 95% of women when used with ______.

Estrogen's nuclear dependent receptors prevent ______ formation in the vascular system

Estrogen's nuclear dependent receptors support tissue maintenance in the ______ and vagina

Estrogen's membrane dependent receptors stimulate ______ growth and reduce the risk of breast cancer

NEST drugs promote nuclear dependent effects and prevent ______ effects

PhexxiTM is a contraceptive vaginal ______.

The vaginal pH range of PhexxiTM is ______.

PhexxiTM has an efficacy of ______% with 'typical use' and ______% when used as directed.

The adverse effects of PhexxiTM include ______.

Hormonal contraception increases the risk of ______.

Hormonal contraception can reduce the risk of ______ or ovarian cancer.

Which compound is the primary estrogen used in oral contraceptives?

What is the effect of unsaturation (double bonds) in Ring B on estrogenic potency?

Which compound has a long half-life of 24-28 hours and is minimally metabolized?

What are non-steroidal compounds with estrogenic activity?

Which of the following is NOT an effect of estrogen on the cardiovascular system?

Which of the following is a clinical use of estrogens?

Which receptor type stimulates breast growth and reduces the risk of breast cancer?

What is the role of NEST drugs in promoting nuclear-dependent effects and preventing membrane-dependent effects?

Which structure in the female reproductive system is responsible for transporting oocytes released from the ovaries to the uterus?

During the menstrual cycle, which structure in the female reproductive system undergoes thinning and dilation in preparation for childbirth?

What is the name of the structure that is formed after ovulation and is responsible for producing progesterone?

What is the site of follicle development in the female reproductive system?

Which of the following is a true statement about progestins?

Which contraceptive method is CI (contraindicated) in patients with renal and/or hepatic impairment?

Which of the following is a characteristic of clomiphene?

Which hormone is responsible for thickening cervical mucus and preventing ovulation?

During which phase of the menstrual cycle is the corpus luteum secreting estrogen, progesterone, and inhibin?

What hormone is a precursor for estrogens in the luteal phase?

Which hormone provides negative feedback to the pituitary, inhibiting FSH release?

What is the function of the uterine tubes in the female reproductive system?

Which of the following is NOT a potential adverse effect of hormonal contraception?

What is the primary mechanism of action for hormonal contraception in preventing pregnancy?

Which of the following is a non-hormonal contraceptive method?

Which compound is a synthetic analog of a natural estrogen synthesized by the fetal liver and present only during pregnancy?

Which of the following is a disadvantage of estrogen-containing contraceptives?

Which contraceptive method has a weight restriction of BMI >30?

Which of the following is a true statement about SERMs?

Which of the following is a true statement about tamoxifen?

Which of the following is a true statement about raloxifene?

Which of the following is a true statement about clomiphene?