The Role of Progestins in Reproductive Health

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Questions and Answers

Which structure in the female reproductive system thins and dilates during childbirth?

  • Cervix (correct)
  • Uterus
  • Myometrium
  • Endometrium

What is the function of the uterine tubes in the female reproductive system?

  • To facilitate implantation
  • To release egg cells
  • To transport sperm and egg cells to the uterus (correct)
  • To provide nutrients to the oocyte

Which structure in the female reproductive system releases egg cells?

  • Cervix
  • Uterus
  • Ovary (correct)
  • Vagina

What is the function of the corpus luteum in the female reproductive system?

<p>To produce hormones (A)</p> Signup and view all the answers

Which of the following is a nuclear ER effect of estrogen?

<p>Prevents plaque formation in the vascular system (D)</p> Signup and view all the answers

Which of the following is a membrane ER effect of estrogen?

<p>Stimulates breast growth (D)</p> Signup and view all the answers

Which type of receptor agonist is Estetrol (NEST)?

<p>Nuclear receptor agonist (A)</p> Signup and view all the answers

Which of the following is a clinical use of estrogens?

<p>Maintain thick endometrium (C)</p> Signup and view all the answers

Which of the following is a non-steroidal compound with estrogenic activity?

<p>Bisphenol A (D)</p> Signup and view all the answers

Which estrogen is the primary one used in oral contraceptives?

<p>Ethinyl estradiol (D)</p> Signup and view all the answers

Which estrogen is 50% less potent than ethinyl estradiol?

<p>Mestranol (D)</p> Signup and view all the answers

Which modification in the steroid nucleus usually reduces estrogenic activity?

<p>C-17 hydroxyl (B)</p> Signup and view all the answers

Which type of contraception prevents ovulation and thickens cervical mucus?

<p>Monophasic combination pills (A)</p> Signup and view all the answers

Which type of contraception is not as effective in preventing ovulation?

<p>Progestin-only pill (B)</p> Signup and view all the answers

Which contraceptive method carries a higher risk of thromboembolism?

<p>Monophasic combination pills (B)</p> Signup and view all the answers

Which contraceptive method is associated with breakthrough bleeding?

<p>Progestin-only pill (A)</p> Signup and view all the answers

Which of the following is a characteristic of SERMs?

<p>They increase estrogen receptor activity in some tissues and inhibit it in others (D)</p> Signup and view all the answers

Which of the following is a characteristic of Tamoxifen?

<p>It is an antagonist in the breast (B)</p> Signup and view all the answers

Which of the following is a characteristic of Raloxifene?

<p>It decreases uterine malignancy risk (C)</p> Signup and view all the answers

Which of the following is a characteristic of Clomiphene?

<p>It stimulates estrogen receptor downregulation (B)</p> Signup and view all the answers

Which contraceptive method has a vaginal pH of 3.5-4.5?

<p>PhexxiTM contraceptive vaginal gel (B)</p> Signup and view all the answers

What is the efficacy of PhexxiTM contraceptive vaginal gel with 'typical use'?

<p>86% (C)</p> Signup and view all the answers

Which contraceptive method is nonhormonal?

<p>Paragard (B)</p> Signup and view all the answers

Which contraceptive method is monophasic and releases EE for 9 days?

<p>Xulane (D)</p> Signup and view all the answers

Which contraceptive method has a lower dose and is not recommended for individuals with a BMI >30?

<p>Twirla (A)</p> Signup and view all the answers

Which contraceptive method is a synthetic analog of a natural estrogen synthesized by the fetal liver and present only during pregnancy?

<p>Nextstellis (estetrol/drospirenone) (D)</p> Signup and view all the answers

What hormone is responsible for the positive feedback to gonadotropin release that leads to ovulation?

<p>Luteinizing hormone (B)</p> Signup and view all the answers

What is the function of the corpus luteum during the luteal phase of the menstrual cycle?

<p>Inhibit gonadotropins and maintain the endometrium (D)</p> Signup and view all the answers

What hormone prevents regression of the corpus luteum and maintains the secretion of estrogen and progesterone until the placenta takes over?

<p>Human chorionic gonadotropin (hCG) (C)</p> Signup and view all the answers

What is the major secretory product of the ovary?

<p>Estrogen (D)</p> Signup and view all the answers

Which of the following is an advantage of daily use of tadalafil (Cialis)?

<p>Better efficacy than on-demand use (A)</p> Signup and view all the answers

Which drug can cause visual disturbances such as blurry vision and color changes?

<p>Sildenafil (B)</p> Signup and view all the answers

Which drug has PDE11 inhibition and can cause myalgia as a side effect?

<p>Tadalafil (Cialis) (A)</p> Signup and view all the answers

Which drug should be taken on an empty stomach for maximum rate of absorption?

<p>Sildenafil (B)</p> Signup and view all the answers

How many attempts should be allowed before admitting failure?

<p>5-8 attempts (A)</p> Signup and view all the answers

Which drug may cause severe hypotension when used concomitantly with nitrates?

<p>All of the above (D)</p> Signup and view all the answers

Which erectile dysfunction medication has a duration of effect of about 4 hours?

<p>Sildenafil (Viagra) (A)</p> Signup and view all the answers

What is the recommended pre-intercourse dose for Vardenafil (Levitra)?

<p>5-20mg (C)</p> Signup and view all the answers

What is the recommended pre-intercourse dose for Tadalafil (Cialis)?

<p>5-20mg (B)</p> Signup and view all the answers

Which erectile dysfunction medication has a daily dose option of 2.5-5mg?

<p>Tadalafil (Cialis) (A)</p> Signup and view all the answers

What is the recommended pre-intercourse dose for Avanafil (Stendra)?

<p>100-200mg (D)</p> Signup and view all the answers

Which erectile dysfunction medication should be taken 60 minutes before sexual stimulation?

<p>Verdenafil (Levitra) (C)</p> Signup and view all the answers

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