Probenecid Flashcards
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Questions and Answers

What is the class of Probenecid?

  • Antibiotic
  • Pain reliever
  • Anti-Gout (correct)
  • Anti-inflammatory
  • What is the mechanism of action (MOA) of Probenecid?

    Promotes excretion from within

    What condition is Probenecid used for?

    Gout

    What is the route of administration for Probenecid?

    <p>Oral</p> Signup and view all the answers

    Which of the following are side effects of Probenecid? (Select all that apply)

    <p>Headache</p> Signup and view all the answers

    What caution should be taken with Probenecid?

    <p>Morphine is highly addictive</p> Signup and view all the answers

    What should be monitored during Probenecid therapy?

    <p>BUN/Creatinine, Ins and Outs, Liver labs, GI upset</p> Signup and view all the answers

    What dietary consideration is advised for patients taking Probenecid?

    <p>Avoid foods high in purine</p> Signup and view all the answers

    How should Probenecid be taken to mitigate stomach issues?

    <p>With food or milk</p> Signup and view all the answers

    Study Notes

    Probenecid Overview

    • Classifies as an Anti-Gout medication.
    • Mechanism of action involves promoting the renal excretion of uric acid.

    Indications

    • Primarily used for managing gout by enhancing uric acid elimination.

    Administration

    • Administered orally for convenience and patient compliance.

    Side Effects

    • Common side effects include:
      • Headache
      • Upset stomach
      • Kidney stones
      • Sore gums

    Precautions

    • Caution advised with morphine due to its addictive properties.
    • Naloxone should be available as an opioid antagonist if required.
    • Close monitoring of liver function is essential when taken with Percocet.

    Patient Assessment

    • Regular monitoring of BUN/creatinine levels is critical.
    • Keep track of patient’s fluid intake and output.
    • Liver lab values should be assessed periodically.
    • Monitor gastrointestinal disturbances closely.

    Patient Education

    • Instruct patients to take medication with food or milk to minimize stomach upset.
    • Advise avoiding foods rich in purines to prevent exacerbating gout symptoms.
    • Encourage increased hydration, specifically drinking plenty of water.

    Dietary Considerations

    • Emphasize the importance of avoiding foods high in purines to help control uric acid levels.

    Special Notes

    • Underlines the significance of promoting uric acid excretion as a therapeutic action.

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    Description

    Test your knowledge on Probenecid, an anti-gout medication. This quiz covers its mechanism of action, uses, administration route, side effects, and cautions. Perfect for students in pharmacology or medicine.

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