Questions and Answers
What is the class of Probenecid?
What is the mechanism of action (MOA) of Probenecid?
Promotes excretion from within
What condition is Probenecid used for?
Gout
What is the route of administration for Probenecid?
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Which of the following are side effects of Probenecid? (Select all that apply)
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What caution should be taken with Probenecid?
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What should be monitored during Probenecid therapy?
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What dietary consideration is advised for patients taking Probenecid?
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How should Probenecid be taken to mitigate stomach issues?
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Study Notes
Probenecid Overview
- Classifies as an Anti-Gout medication.
- Mechanism of action involves promoting the renal excretion of uric acid.
Indications
- Primarily used for managing gout by enhancing uric acid elimination.
Administration
- Administered orally for convenience and patient compliance.
Side Effects
- Common side effects include:
- Headache
- Upset stomach
- Kidney stones
- Sore gums
Precautions
- Caution advised with morphine due to its addictive properties.
- Naloxone should be available as an opioid antagonist if required.
- Close monitoring of liver function is essential when taken with Percocet.
Patient Assessment
- Regular monitoring of BUN/creatinine levels is critical.
- Keep track of patient’s fluid intake and output.
- Liver lab values should be assessed periodically.
- Monitor gastrointestinal disturbances closely.
Patient Education
- Instruct patients to take medication with food or milk to minimize stomach upset.
- Advise avoiding foods rich in purines to prevent exacerbating gout symptoms.
- Encourage increased hydration, specifically drinking plenty of water.
Dietary Considerations
- Emphasize the importance of avoiding foods high in purines to help control uric acid levels.
Special Notes
- Underlines the significance of promoting uric acid excretion as a therapeutic action.
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Description
Test your knowledge on Probenecid, an anti-gout medication. This quiz covers its mechanism of action, uses, administration route, side effects, and cautions. Perfect for students in pharmacology or medicine.