Probenecid Flashcards
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Questions and Answers

What is the class of Probenecid?

  • Antibiotic
  • Pain reliever
  • Anti-Gout (correct)
  • Anti-inflammatory

What is the mechanism of action (MOA) of Probenecid?

Promotes excretion from within

What condition is Probenecid used for?

Gout

What is the route of administration for Probenecid?

<p>Oral</p> Signup and view all the answers

Which of the following are side effects of Probenecid? (Select all that apply)

<p>Headache (B), Sore Gums (C), Upset Stomach (D), Kidney Stones (E)</p> Signup and view all the answers

What caution should be taken with Probenecid?

<p>Morphine is highly addictive</p> Signup and view all the answers

What should be monitored during Probenecid therapy?

<p>BUN/Creatinine, Ins and Outs, Liver labs, GI upset</p> Signup and view all the answers

What dietary consideration is advised for patients taking Probenecid?

<p>Avoid foods high in purine</p> Signup and view all the answers

How should Probenecid be taken to mitigate stomach issues?

<p>With food or milk</p> Signup and view all the answers

Study Notes

Probenecid Overview

  • Classifies as an Anti-Gout medication.
  • Mechanism of action involves promoting the renal excretion of uric acid.

Indications

  • Primarily used for managing gout by enhancing uric acid elimination.

Administration

  • Administered orally for convenience and patient compliance.

Side Effects

  • Common side effects include:
    • Headache
    • Upset stomach
    • Kidney stones
    • Sore gums

Precautions

  • Caution advised with morphine due to its addictive properties.
  • Naloxone should be available as an opioid antagonist if required.
  • Close monitoring of liver function is essential when taken with Percocet.

Patient Assessment

  • Regular monitoring of BUN/creatinine levels is critical.
  • Keep track of patient’s fluid intake and output.
  • Liver lab values should be assessed periodically.
  • Monitor gastrointestinal disturbances closely.

Patient Education

  • Instruct patients to take medication with food or milk to minimize stomach upset.
  • Advise avoiding foods rich in purines to prevent exacerbating gout symptoms.
  • Encourage increased hydration, specifically drinking plenty of water.

Dietary Considerations

  • Emphasize the importance of avoiding foods high in purines to help control uric acid levels.

Special Notes

  • Underlines the significance of promoting uric acid excretion as a therapeutic action.

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Description

Test your knowledge on Probenecid, an anti-gout medication. This quiz covers its mechanism of action, uses, administration route, side effects, and cautions. Perfect for students in pharmacology or medicine.

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