Podcast
Questions and Answers
What is the main target in pharmacokinetics?
What is the main target in pharmacokinetics?
- Drug delivery systems
- Minimum toxic concentration (MTC)
- Maximum effect concentration (MEC)
- Plasma/blood drug concentration between MEC and MTC (correct)
What is the theoretical framework for determining the time course of drug absorption, distribution, metabolism, and excretion?
What is the theoretical framework for determining the time course of drug absorption, distribution, metabolism, and excretion?
- Pharmacokinetics (correct)
- Pharmacodynamics
- Therapeutic effects
- Optimal drug delivery strategies
What must the desired steady-state Cp be in order to be effective clinically but not toxic?
What must the desired steady-state Cp be in order to be effective clinically but not toxic?
- Equal to MEC
- Greater than MTC
- Greater than MEC and less than MTC (correct)
- Less than MEC
What does the pharmacokinetic model translate the dose into?
What does the pharmacokinetic model translate the dose into?
What does the pharmacodynamic model convert Ce into?
What does the pharmacodynamic model convert Ce into?
What does Cp typically correspond with in terms of drug effect?
What does Cp typically correspond with in terms of drug effect?
In the LADME scheme, what does 'Liberation' refer to?
In the LADME scheme, what does 'Liberation' refer to?
What are the dynamic processes reflecting following drug administration by any route?
What are the dynamic processes reflecting following drug administration by any route?
What is critical to the development of various drug delivery technologies?
What is critical to the development of various drug delivery technologies?
In case a drug is administered directly into the systemic circulation, what happens to the absorption process?
In case a drug is administered directly into the systemic circulation, what happens to the absorption process?
