Principles of Pharmacokinetics Quiz

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10 Questions

What is the main target in pharmacokinetics?

Plasma/blood drug concentration between MEC and MTC

What is the theoretical framework for determining the time course of drug absorption, distribution, metabolism, and excretion?

Pharmacokinetics

What must the desired steady-state Cp be in order to be effective clinically but not toxic?

Greater than MEC and less than MTC

What does the pharmacokinetic model translate the dose into?

Plasma concentration Cp

What does the pharmacodynamic model convert Ce into?

Measured effect

What does Cp typically correspond with in terms of drug effect?

The desired steady-state drug plasma concentration

In the LADME scheme, what does 'Liberation' refer to?

The release of the drug from the dosage form

What are the dynamic processes reflecting following drug administration by any route?

Drug absorption, distribution, and elimination

What is critical to the development of various drug delivery technologies?

Application of pharmacokinetics

In case a drug is administered directly into the systemic circulation, what happens to the absorption process?

There is no absorption process

Test your knowledge of the theoretical framework for determining the time course of drug absorption, distribution, metabolism, and excretion. This quiz covers principles important for developing drug delivery systems targeting specific drug concentrations.

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