Principles of Pharmacokinetics Quiz

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What is the main target in pharmacokinetics?

Drug delivery systems

Minimum toxic concentration (MTC)

Maximum effect concentration (MEC)

Plasma/blood drug concentration between MEC and MTC (correct)

What is the theoretical framework for determining the time course of drug absorption, distribution, metabolism, and excretion?

Pharmacokinetics (correct)

Pharmacodynamics

Therapeutic effects

Optimal drug delivery strategies

What must the desired steady-state Cp be in order to be effective clinically but not toxic?

Equal to MEC

Greater than MTC

Greater than MEC and less than MTC (correct)

Less than MEC

What does the pharmacokinetic model translate the dose into?

Plasma concentration Cp Signup and view all the answers

What does the pharmacodynamic model convert Ce into?

Measured effect Signup and view all the answers

What does Cp typically correspond with in terms of drug effect?

The desired steady-state drug plasma concentration Signup and view all the answers

In the LADME scheme, what does 'Liberation' refer to?

The release of the drug from the dosage form Signup and view all the answers

What are the dynamic processes reflecting following drug administration by any route?

Drug absorption, distribution, and elimination Signup and view all the answers

What is critical to the development of various drug delivery technologies?

Application of pharmacokinetics Signup and view all the answers

In case a drug is administered directly into the systemic circulation, what happens to the absorption process?

There is no absorption process Signup and view all the answers

Principles of Pharmacokinetics Quiz

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Questions and Answers

What is the main target in pharmacokinetics?

What is the theoretical framework for determining the time course of drug absorption, distribution, metabolism, and excretion?

What must the desired steady-state Cp be in order to be effective clinically but not toxic?

What does the pharmacokinetic model translate the dose into?

What does the pharmacodynamic model convert Ce into?

What does Cp typically correspond with in terms of drug effect?

In the LADME scheme, what does 'Liberation' refer to?

What are the dynamic processes reflecting following drug administration by any route?

What is critical to the development of various drug delivery technologies?

In case a drug is administered directly into the systemic circulation, what happens to the absorption process?

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