Podcast
Questions and Answers
What is the target in pharmacokinetics, generally?
What is the target in pharmacokinetics, generally?
- Maximum effect concentration (MEC)
- Plasma/blood drug concentration (correct)
- Drug absorption, distribution, metabolism, and excretion
- Minimum toxic concentration (MTC)
In pharmacokinetics, what must the desired steady-state Cp be in order to be effective clinically but not toxic?
In pharmacokinetics, what must the desired steady-state Cp be in order to be effective clinically but not toxic?
- Greater than the MEC and less than the MTC (correct)
- Equal to the MTC
- Lower than the MTC
- Equal to the MEC
What does the pharmacokinetic model translate the dose into?
What does the pharmacokinetic model translate the dose into?
- MEC
- MTC
- Plasma concentration (correct)
- Drug absorption
What does the pharmacodynamic model convert the drug concentration at the effect site into?
What does the pharmacodynamic model convert the drug concentration at the effect site into?
What is the primary focus of pharmaceutical scientists in biopharmaceutics?
What is the primary focus of pharmaceutical scientists in biopharmaceutics?
What is the theoretical framework of principles for determining the time course of drug absorption, distribution, metabolism, and excretion?
What is the theoretical framework of principles for determining the time course of drug absorption, distribution, metabolism, and excretion?
What is the primary focus of most drug delivery devices in terms of achieving concentration?
What is the primary focus of most drug delivery devices in terms of achieving concentration?
Which process is critical to the development of various drug delivery technologies?
Which process is critical to the development of various drug delivery technologies?
What does LADME stand for in the context of drug pharmacokinetics?
What does LADME stand for in the context of drug pharmacokinetics?
What does liberation encompass in the LADME scheme?
What does liberation encompass in the LADME scheme?
In what circumstances is there no absorption process following drug administration?
In what circumstances is there no absorption process following drug administration?
What processes reflect drug absorption, distribution, and elimination following drug administration?
What processes reflect drug absorption, distribution, and elimination following drug administration?
What is the relationship between Cp and the corresponding effect for most drugs?
What is the relationship between Cp and the corresponding effect for most drugs?
Flashcards are hidden until you start studying
