Principles of Ocular Drug Administration Quiz

Which of the following is NOT a consideration for ocular history when using drugs for ocular examination, diagnosis, or treatment?

What should be considered when assessing medical history for ocular drug administration?

Which type of medications may result in a cardiovascular effect when combined with Phenylephrine?

What effect may be seen when combining topical steroid with a family history of primary open-angle glaucoma (POAG)?

Which of the following is an example of an ocular history consideration when using drugs for ocular diagnosis or treatment?

What is a potential concern when using drugs for ocular examination, diagnosis, or treatment in the presence of inflammation?

Which component of a finished drug product is also known as an excipient?

What is the role of a wetting agent in a finished drug product?

Which component of a finished drug product functions as a preservative?

What term is used to refer to the tonicity equivalent in a finished drug product?

What is the major functional barrier to ocular penetration?

Which part of the eye is a major source of drug metabolizing enzymes?

Which part of the eye serves as a depot for injected or surgically implanted drugs?

What property of drugs influences which tissues act as reservoirs versus barriers in ocular drug kinetics?

What role does the aqueous humor play in the route of drugs in the eye?

What part of the eye prevents drug movement from blood to vitreous/retina?

What pH environment is more compatible with the epithelium than neutral or acidic for ophthalmic solutions?

What type of drugs are resisted by healthy epithelium due to its continuous layer of plasma membrane to tear film?

Which part of the eye serves as a reservoir for hydrophilic drugs?

Which part of the eye is characterized by nonspecific or low affinity binding of lipophilic drugs?

Which part of the eye is a major site of absorption and is biphasic in solubility for corneal penetration?

What property of drugs is responsible for their distribution and bioavailability in ocular drug administration?

Which category of pregnancy drugs presents a definite fetal risk and should be avoided?

Which condition is a contraindication for the use of phenylephrine (especially 10%)?

What is the main concern regarding the use of systemic steroids in patients with diabetes mellitus?

Which drug is contraindicated in congestive heart disease, bradycardia, and AV block?

According to the updated drug labeling, which category of drugs has no risk to the fetus?

What information does the 'Lactation' subsection of drug labeling provide?

Which section of the updated drug labeling includes information on pregnancy testing and contraception?

Which drug is contraindicated in hypertension?

Which condition is a contraindication for the use of cyclopentolate?

According to the updated drug labeling, which category of drugs presents a risk to the fetus that cannot be ruled out?

Which section of the updated drug labeling provides detailed information on potential risks to the developing fetus?

What does the 'Compartment' refer to in pharmacokinetics?

According to Fick’s first law of diffusion, what affects drug absorption?

Which type of kinetics is most common in ocular drug movement?

What is the characteristic of zero-order kinetics?

Which vessels eliminate drugs via active transport?

What characterizes extended release medications compared to immediate release medications?

What is the advantage of prodrugs?

What happens to dipivalyl epinephrine in the cornea?

What is valacyclovir classified as?

What characterizes soft drugs?

What defines site specific drugs?

What is the characteristic of hard drugs?

What distinguishes immediate release medications from extended release medications?

What is the main characteristic of a prodrug?

Which type of drugs are produced/developed from living organisms or contain components of living organisms?

What are monoclonal antibodies (mAB) primarily used for?

How are biosimilars named?

What does osmolarity measure?

What is the effect of hyperosmolar tears on the corneal epithelial cells?

What is the main purpose of using preservatives in drug formulations?

What type of preservative is benzalkonium chloride (BAC or BAK)?

What is a biologic?

What distinguishes monoclonal antibodies (mAB) from human antibodies?

What does osmolarity measure?

What is the main effect of benzalkonium chloride as a preservative?

What is the main effect of chlorobutanol as a preservative?

What is the main effect of polyquaternium-1 (Polyquad) as a preservative?

What is the main effect of stabilized oxychloro complex (Purite) as a preservative?

What is the main effect of sodium perborate as a preservative?

What is the main effect of thimerosal as a preservative?

What is the main effect of Sorbate (sorbic acid) as a preservative?

What is the main difference between benzalkonium chloride and chlorobutanol as preservatives?

What is the main difference between polyquaternium-1 (Polyquad) and stabilized oxychloro complex (Purite) as preservatives?

What is the main difference between thimerosal and sodium perborate as preservatives?

What is the main difference between sorbate (sorbic acid) and SofZia as preservatives?

Which type of preservative causes bacterial cell death by interacting with lipid components in the cell membrane?