Podcast
Questions and Answers
Which of the following is a key factor in the selection of an antimicrobial agent?
Which of the following is a key factor in the selection of an antimicrobial agent?
- Ability to alter the natural flora and cause superinfection
- Ability to penetrate the blood-brain barrier
- Severity of the patient's infection (correct)
- Effectiveness against a wide variety of microorganisms
What is the primary purpose of narrow spectrum antibiotics?
What is the primary purpose of narrow spectrum antibiotics?
- To alter the nature of the natural flora and cause superinfection
- To act on a single or limited group of microorganisms (correct)
- To be effective against both gram-positive and gram-negative bacteria
- To affect a wide variety of microbial species
Which of the following is a key host factor that can influence the selection of an antimicrobial agent?
Which of the following is a key host factor that can influence the selection of an antimicrobial agent?
- Ability to penetrate the blood-brain barrier
- Renal dysfunction (correct)
- Effectiveness against a wide variety of microorganisms
- Severity of the patient's infection
What is the primary purpose of broad spectrum antibiotics?
What is the primary purpose of broad spectrum antibiotics?
Which of the following is a key factor that can limit the penetration of an antibiotic to the site of infection?
Which of the following is a key factor that can limit the penetration of an antibiotic to the site of infection?
Which of the following is a key principle in the selection of the most appropriate antibiotic for a given infection?
Which of the following is a key principle in the selection of the most appropriate antibiotic for a given infection?
Which of the following is NOT one of the main cellular targets of antibiotics?
Which of the following is NOT one of the main cellular targets of antibiotics?
When selecting an antimicrobial agent, which factor should be given the LEAST consideration?
When selecting an antimicrobial agent, which factor should be given the LEAST consideration?
Which of the following statements about chemotherapeutic spectra is INCORRECT?
Which of the following statements about chemotherapeutic spectra is INCORRECT?
What is the primary advantage of using combination antimicrobial therapy?
What is the primary advantage of using combination antimicrobial therapy?
Which of the following is NOT a mechanism of antimicrobial resistance?
Which of the following is NOT a mechanism of antimicrobial resistance?
What is the primary mechanism by which genetic alterations can lead to drug resistance in microorganisms?
What is the primary mechanism by which genetic alterations can lead to drug resistance in microorganisms?
Which of the following mechanisms of antibiotic resistance involves the modification of the target site of the antibiotic?
Which of the following mechanisms of antibiotic resistance involves the modification of the target site of the antibiotic?
Which of the following is an example of a mechanism that leads to decreased accumulation of an antibiotic within a resistant microorganism?
Which of the following is an example of a mechanism that leads to decreased accumulation of an antibiotic within a resistant microorganism?
What is the primary mechanism by which $eta$-lactamases confer antibiotic resistance?
What is the primary mechanism by which $eta$-lactamases confer antibiotic resistance?
Which of the following is a potential adverse effect that may develop during antimicrobial therapy, even though antibiotics exhibit selective toxicity?
Which of the following is a potential adverse effect that may develop during antimicrobial therapy, even though antibiotics exhibit selective toxicity?
How can drug resistance be transferred between microorganisms?
How can drug resistance be transferred between microorganisms?
Which of the following is NOT part of the spectrum of activity for Penicillin G?
Which of the following is NOT part of the spectrum of activity for Penicillin G?
Which of the following is the broadest spectrum penicillin?
Which of the following is the broadest spectrum penicillin?
Which of the following penicillins has increased activity against gram-negative bacteria compared to Penicillin G?
Which of the following penicillins has increased activity against gram-negative bacteria compared to Penicillin G?
Which of the following adverse effects is NOT associated with penicillin use?
Which of the following adverse effects is NOT associated with penicillin use?
Which of the following penicillins is used to treat oropharyngeal infections caused by streptococci and pneumococci?
Which of the following penicillins is used to treat oropharyngeal infections caused by streptococci and pneumococci?
Which of the following penicillins is used to treat Pseudomonas aeruginosa infections?
Which of the following penicillins is used to treat Pseudomonas aeruginosa infections?
What is the primary target site of b-Lactam antibiotics?
What is the primary target site of b-Lactam antibiotics?
Which type of killing is associated with b-Lactam antibiotics?
Which type of killing is associated with b-Lactam antibiotics?
Which antibiotic is often used in combination with aminoglycosides due to its synergistic effects?
Which antibiotic is often used in combination with aminoglycosides due to its synergistic effects?
Which group of antibiotics includes Monobactam?
Which group of antibiotics includes Monobactam?
Which type of penicillin is administered via intravenous or intramuscular routes?
Which type of penicillin is administered via intravenous or intramuscular routes?
What is the main mechanism of action of b-Lactam antibiotics on bacterial cells?
What is the main mechanism of action of b-Lactam antibiotics on bacterial cells?
