Primidone Pharmacology Quiz

Study Notes

Primidone Overview

Primidone is marketed under the trade name Mysoline.
Classification falls under Category D, indicating potential risks during pregnancy, and it is classified as an anticonvulsant.

Indications and Therapeutic Use

Primidone is primarily indicated for the treatment of essential tremor.

Mechanism of Action

It functions by decreasing neuronal excitability.
It increases the threshold for electric stimulation in the motor cortex, which can help manage symptoms.

Dosage Information

The safe dosage commonly prescribed is 100-125 mg taken at bedtime.

Contraindications

Not suitable for patients with hypersensitivity to primidone or phenobarbital.
Contraindicated in individuals with porphyria.

Precautions

All patients on Primidone should be monitored for increased risk of suicidal thoughts.
Caution is advised in cases of severe liver disease.

Adverse Effects

May cause suicidal thoughts, ataxia, drowsiness, and vertigo.
Other potential side effects include anorexia, visual changes, dyspnea, edema, and orthostatic hypotension.
Could lead to serious issues like drug-induced hepatitis, nausea/vomiting, alopecia, rash, blood dyscrasias, megaloblastic anemia, and folic acid deficiency.

Assessment and Monitoring

Regular assessment of seizure activity is crucial.
Evaluate for signs of folic acid deficiency.
Monitor for any significant changes in patient behavior.

Patient Teaching

Inform patients about the possibility of behavioral changes and drowsiness.
Advise taking missed doses as soon as possible within one hour of the next dose.
Patients should notify healthcare providers before undergoing treatment or surgery.

Description

Test your knowledge on Primidone, a key anticonvulsant medication, through these flashcards. Explore aspects such as its trade name, indications, mechanism of action, and safe dosage practices. Perfect for students and professionals in pharmacology or medicine.