Podcast
Questions and Answers
What's the primary site of absorption after oral administration?
What's the primary site of absorption after oral administration?
- Liver
- Small intestines (correct)
- Kidney
- Stomach
Extended-release formulations are devised to control drug release at a reduced rate (Ka < K ), resulting in ____ drug level in plasma
Extended-release formulations are devised to control drug release at a reduced rate (Ka < K ), resulting in ____ drug level in plasma
sustained
How many half lives for a drug to reach steady state?
How many half lives for a drug to reach steady state?
- 2
- 12
- 8
- 5 (correct)
Oral ______ ( F ) is determined by comparing the drug exposure following PO with that of IV dosing
Oral ______ ( F ) is determined by comparing the drug exposure following PO with that of IV dosing
Which of these Drugs is not CV?
Which of these Drugs is not CV?
Which of these drugs in CIII
Which of these drugs in CIII
Which of these drugs Lowers BC concentrations
Which of these drugs Lowers BC concentrations
Which of these drugs does NOT lower oral contraception concentration?
Which of these drugs does NOT lower oral contraception concentration?
The T2 of focal seizures is ___ minutes
The T2 of focal seizures is ___ minutes
Which is NOT an initial treatment choice for status epilectus?
Which is NOT an initial treatment choice for status epilectus?
Which of these is first line for absence seizures
Which of these is first line for absence seizures
Which is NOT first line for tonic clonic seizures
Which is NOT first line for tonic clonic seizures
Which does NOT have a sodium factor of 1
Which does NOT have a sodium factor of 1
Which is a warning of lacosamide?
Which is a warning of lacosamide?
Which is true about Ethosuximide?
Which is true about Ethosuximide?
Which ASM is contraindicationed in sufla allergies
Which ASM is contraindicationed in sufla allergies
Which has the lowest risk of hyponatremia
Which has the lowest risk of hyponatremia
T/F: Hyponatremia is more common with Oxcarbazepine than with Carbmazepine?
T/F: Hyponatremia is more common with Oxcarbazepine than with Carbmazepine?
Which is a UGT inhibitor
Which is a UGT inhibitor
What is the therapeutic range of Valproate?
What is the therapeutic range of Valproate?
Match the valproate concentration with what happens
Match the valproate concentration with what happens
What's the average valproate clearance for adults with liver failure
What's the average valproate clearance for adults with liver failure
What's the average valproate clearance for normal adults
What's the average valproate clearance for normal adults
Which form of Topiramate should alcohol be avoided for 6 hours before and after taking
Which form of Topiramate should alcohol be avoided for 6 hours before and after taking
Which has a box warning for serious neuropsychiatric events?
Which has a box warning for serious neuropsychiatric events?
If child-pugh score is >___, reduce valproate dose by ___ %
If child-pugh score is >___, reduce valproate dose by ___ %
If you want to increase concentration of Valproate, increase dose by ___ % of predicted dose
If you want to increase concentration of Valproate, increase dose by ___ % of predicted dose
T/F: Cirrhosis decrease volume of distribution
T/F: Cirrhosis decrease volume of distribution
What's the average volume of distribution for phenytoin
What's the average volume of distribution for phenytoin
T/F: Carbamazepine and phenytoin are UGT inducers
T/F: Carbamazepine and phenytoin are UGT inducers
Which ASM is NOT contraindicated in Familial Short QT syndrome
Which ASM is NOT contraindicated in Familial Short QT syndrome
Primidone is metablized by CYP____ into Phentobarbital and PEMA
Primidone is metablized by CYP____ into Phentobarbital and PEMA
T/F: Pentobarbital is a GABA-A Pam that increases channel opening time
T/F: Pentobarbital is a GABA-A Pam that increases channel opening time
Which drug is an NMDA-R blocker
Which drug is an NMDA-R blocker
Felbamate should be discontinued if ___ are 2x normal upper limit normal
Felbamate should be discontinued if ___ are 2x normal upper limit normal
What is a common first-line agent for focal seziures according to the text?
What is a common first-line agent for focal seziures according to the text?
Which drug DOES NOT require renal dose adjustments?
Which drug DOES NOT require renal dose adjustments?
Which drug should be taken with food?
Which drug should be taken with food?
Pregnant women suffering from tonic clonic seizures. Pick the best one to give her
Pregnant women suffering from tonic clonic seizures. Pick the best one to give her
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