Potassium Chloride (KCl) CHP 25 Flashcards
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Questions and Answers

What is the therapeutic class of Potassium Chloride?

  • Antacid
  • Analgesic
  • Drug for hypokalemia (correct)
  • Diuretic

What is the pharmacologic class of Potassium Chloride?

  • Antidepressant
  • Electrolyte, potassium supplement (correct)
  • Antibiotic
  • Corticosteroid

What are some actions and uses of Potassium Chloride?

Potassium chloride is used for preventing or treating hypokalemia and mild forms of alkalosis.

Potassium Chloride can be crushed before administration.

<p>False (B)</p> Signup and view all the answers

What are common adverse effects of Potassium Chloride?

<p>Nausea and vomiting (C)</p> Signup and view all the answers

Potassium Chloride is contraindicated in patients with hyperkalemia.

<p>True (A)</p> Signup and view all the answers

What interactions should be considered when prescribing Potassium Chloride?

<p>It interacts with potassium-sparing diuretics and ACE inhibitors.</p> Signup and view all the answers

How does Potassium Chloride affect lab tests?

<p>It increases the serum potassium level.</p> Signup and view all the answers

What is a treatment method for suspected overdose of Potassium Chloride?

<p>Withhold potassium-sparing diuretics and administer IV dextrose solution with insulin.</p> Signup and view all the answers

Flashcards

What is Potassium Chloride (KCl)?

Potassium Chloride (KCl) is a medication primarily used to treat low potassium levels in the body (hypokalemia). It is classified as an electrolyte and potassium supplement, meaning it replenishes the body's potassium stores.

How is Potassium Chloride administered?

Potassium Chloride can be administered orally or intravenously. Oral forms are preferred for preventing or treating mild hypokalemia, while IV administration is reserved for severe cases and certain conditions.

What are important safety considerations for Potassium Chloride?

While Potassium Chloride is generally safe when administered correctly, certain precautions must be taken to avoid complications. For example, oral forms should be diluted with water to prevent irritation, and IV administration should be slow to prevent cardiac issues.

How does Potassium Chloride interact with diuretics?

Potassium Chloride, when used in conjunction with diuretics like loop or thiazide diuretics, can help prevent potassium depletion. This combination ensures that the diuretics' effects don't lead to dangerously low potassium levels.

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What are common side effects of Potassium Chloride?

One common side effect of Potassium Chloride is nausea and vomiting, usually due to irritation of the gastrointestinal tract. Taking it with meals or antacids can help reduce this discomfort.

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When is Potassium Chloride contraindicated?

Potassium Chloride is contraindicated in cases of hyperkalemia (high potassium levels), chronic kidney disease, certain acid-base imbalances, severe dehydration, extensive tissue breakdown, and adrenal insufficiency. It's also not recommended with potassium-sparing diuretics as this combination increases hyperkalemia risk.

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What drug interactions should be considered with Potassium Chloride?

Potassium Chloride can interact with other medications, especially potassium-sparing diuretics and ACE inhibitors, increasing the risk of hyperkalemia. It's crucial to inform your doctor about all medications you are taking to avoid potential interactions.

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How is Potassium Chloride overdose treated?

Overdosing on Potassium Chloride can lead to dangerous hyperkalemia. Treatment involves withholding potassium-rich foods and medications, using IV dextrose and insulin to lower potassium levels, and possibly administering medications like polystyrene sulfonate or patiromer to enhance potassium elimination.

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Why is monitoring potassium levels important when taking Potassium Chloride?

Because Potassium Chloride is known to increase potassium levels in the blood, regular monitoring of serum potassium levels is crucial to prevent complications. This helps ensure that the medication is being used effectively without causing any harmful side effects.

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Study Notes

Potassium Chloride (KCl) Overview

  • Therapeutic class: drug for hypokalemia; treats low potassium levels in the body.
  • Pharmacologic class: classified as an electrolyte and potassium supplement.

Actions and Uses

  • Preferred for preventing or treating hypokalemia; also used for mild alkalosis.
  • Available in various forms: tablets, powders, and flavored liquids.
  • Should be diluted with water to prevent gastrointestinal irritation; risk of peptic ulcers.
  • IV administration must be slow; bolus injections can cause cardiac arrest.
  • Commonly prescribed with loop or thiazide diuretics to prevent potassium depletion.

Administration Alerts

  • Administer oral forms while patient is upright to avoid esophagitis.
  • Do not crush or chew tablets; dilute liquid forms before oral or nasogastric administration.
  • IV potassium should not exceed 10 mEq/h; care needed to prevent extravasation.
  • Classified as pregnancy category A.

Adverse Effects

  • Common side effects include nausea and vomiting due to GI irritation.
  • Can be taken with meals or antacids to reduce gastric distress.
  • IV use may result in phlebitis and venous irritation; use larger vessels to minimize risks.
  • Serious risks include hyperkalemia, especially if taken with potassium-sparing diuretics.
  • Chronic kidney disease (CKD) can exacerbate hyperkalemia risk, as kidneys excrete over 90% of potassium.

Contraindications

  • Contraindicated in cases of hyperkalemia, CKD, systemic acidosis, severe dehydration, extensive tissue breakdown, adrenal insufficiency, and use of potassium-sparing diuretics.

Drug-Drug Interactions

  • Interactions increase hyperkalemia risk when taken with potassium-sparing diuretics and angiotensin-converting enzyme (ACE) inhibitors.

Lab Tests

  • Increases serum potassium levels; monitor levels to prevent complications.

Treatment of Overdose

  • Withhold potassium-sparing diuretics and potassium-rich foods/medications.
  • Administer IV dextrose solution with regular insulin to lower potassium levels.
  • Sodium bicarbonate may be given to correct acidosis.
  • Use polystyrene sulfonate or patiromer to enhance potassium elimination.

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Test your knowledge on Potassium Chloride with these flashcards. Each card covers important aspects like therapeutic class, pharmacologic class, and actions and uses of KCl. Perfect for students studying pharmacology or related medical fields.

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