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Post-analysis in Clinical Laboratory Testing

Explore the post-analysis phase in clinical laboratory testing focusing on two-step review processes for analytic correctness and clinical significance. Learn about the use of flags and alarms to prevent the release of erroneous results.

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@StylishAlien
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Questions and Answers

Most laboratories utilize a variety of flags or alarms to prevent the release of ______ results

erroneous

Automated analyzers can flag specimens that require additional or repeat testing before results are ______

released

Flags can indicate a problem with the specimen or an issue with the ______

result

Frequent cause of inadequate samples is the presence of high concentrations of interfering substances such as ______

<p>lipids</p> Signup and view all the answers

Samples that could potentially contain qualitative abnormalities are flagged for preparation of a blood smear and further ______

<p>evaluation</p> Signup and view all the answers

Laboratory results must undergo a two-step post-analytic review for analytic correctness and for clinical significance for the ______

<p>patient</p> Signup and view all the answers

Post-analysis: Flags for Problematic Results if the analyte falls above the linear range, many instruments can automatically dilute and reanalyze the sample. If an analyte concentration falls below the linear range, the sample is usually reported as “less than the limit of ________.”

<p>detection</p> Signup and view all the answers

Delta checks are defined as comparing a current laboratory result with results obtained on a previous specimen from the same ________.

<p>patient</p> Signup and view all the answers

Critical values, also known as a panic value, is a laboratory result that may represent a life-threatening situation that may not otherwise be readily ________.

<p>detectable</p> Signup and view all the answers

Sensitivity is the probability of a positive result in a person with the disease (true-positive rate). Specificity is the probability of a negative result in a person without disease (true-negative ________).

<p>rate</p> Signup and view all the answers

Screening tests require high sensitivity so that no case is missed. Confirmatory tests require high specificity to be certain of the ________.

<p>diagnosis</p> Signup and view all the answers

The likelihood ratio of a test changes as the cut-off value defining disease and non-disease is ________.

<p>varied</p> Signup and view all the answers

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