Polypharmacy in Older Adults
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Questions and Answers

What is the increased likelihood of becoming frail within a 3-year period for patients taking five or more medications?

  • Twice as likely
  • Three times more likely
  • Four times more likely
  • 1.5 times more likely (correct)

    • What is the likelihood of being prescribed an inappropriate medication for frail patients compared to non-frail patients?

  • Three times more likely
  • Twice as likely (correct)
  • Four times more likely
  • Half as likely

    • What is a consequence of polypharmacy on patients and their families or carers?

  • Unknown impact
  • Negative impact (correct)
  • No impact
  • Improved quality of life

    • What is a characteristic of the frailty syndrome?

    <p>Susceptibility to side-effects of medications</p> Signup and view all the answers

    What is an aspect of the 'Medications' principle in the 5Ms?

    <p>Polypharmacy and deprescribing</p> Signup and view all the answers

    Why are experimental studies often unfeasible in polypharmacy research?

    <p>Due to ethical concerns</p> Signup and view all the answers

    What is a characteristic of observational studies in polypharmacy research?

    <p>Identifying associations between illness and medication</p> Signup and view all the answers

    What is a goal of deprescribing in the context of the 5Ms?

    <p>Reducing unnecessary medications</p> Signup and view all the answers

    Study Notes

    The Impact of Polypharmacy

    • Older patients taking five or more medications are 1.5 times more likely to become frail within a 3-year period than those who take less than five medications.
    • Frail patients are twice as likely to be prescribed an inappropriate medication than patients who are not experiencing frailty.
    • Polypharmacy can negatively impact patients and their families or carers.
    • Frailty syndromes include falls, cognitive impairment, incontinence, immobility, and susceptibility to side-effects of medications.
    • Medications can cause or contribute to all of these syndromes.

    The 5Ms

    • The 5Ms principles and actions are relevant to deprescribing.
    • Mind: Mentation, dementia, delirium, depression.
    • Mobility: Impaired gait and balance, fall injury prevention.
    • Medications: Polypharmacy, deprescribing, adverse medication effects, medication burden.
    • Multi-complexity: Multi-morbidity, complex bio-psychosocial situations.
    • Matters most: Each patient has meaningful health outcome goals and care preferences.

    Polypharmacy Research

    • Determining cause and effect is difficult in polypharmacy research.
    • Authors rely on identifying the strength of an association between an illness and a specific medication.
    • Observational studies (e.g., cohorts) are typically used in polypharmacy research.
    • Experimental studies are often unfeasible in this field.
    • Observational research has identified risk factors for older persons taking multiple medications.

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    Description

    This quiz assesses understanding of polypharmacy's impact on older adults, including the link between multiple medications and frailty.

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