Podcast
Questions and Answers
What is the increased likelihood of becoming frail within a 3-year period for patients taking five or more medications?
What is the increased likelihood of becoming frail within a 3-year period for patients taking five or more medications?
What is the likelihood of being prescribed an inappropriate medication for frail patients compared to non-frail patients?
What is the likelihood of being prescribed an inappropriate medication for frail patients compared to non-frail patients?
What is a consequence of polypharmacy on patients and their families or carers?
What is a consequence of polypharmacy on patients and their families or carers?
What is a characteristic of the frailty syndrome?
What is a characteristic of the frailty syndrome?
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What is an aspect of the 'Medications' principle in the 5Ms?
What is an aspect of the 'Medications' principle in the 5Ms?
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Why are experimental studies often unfeasible in polypharmacy research?
Why are experimental studies often unfeasible in polypharmacy research?
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What is a characteristic of observational studies in polypharmacy research?
What is a characteristic of observational studies in polypharmacy research?
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What is a goal of deprescribing in the context of the 5Ms?
What is a goal of deprescribing in the context of the 5Ms?
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Study Notes
The Impact of Polypharmacy
- Older patients taking five or more medications are 1.5 times more likely to become frail within a 3-year period than those who take less than five medications.
- Frail patients are twice as likely to be prescribed an inappropriate medication than patients who are not experiencing frailty.
- Polypharmacy can negatively impact patients and their families or carers.
- Frailty syndromes include falls, cognitive impairment, incontinence, immobility, and susceptibility to side-effects of medications.
- Medications can cause or contribute to all of these syndromes.
The 5Ms
- The 5Ms principles and actions are relevant to deprescribing.
- Mind: Mentation, dementia, delirium, depression.
- Mobility: Impaired gait and balance, fall injury prevention.
- Medications: Polypharmacy, deprescribing, adverse medication effects, medication burden.
- Multi-complexity: Multi-morbidity, complex bio-psychosocial situations.
- Matters most: Each patient has meaningful health outcome goals and care preferences.
Polypharmacy Research
- Determining cause and effect is difficult in polypharmacy research.
- Authors rely on identifying the strength of an association between an illness and a specific medication.
- Observational studies (e.g., cohorts) are typically used in polypharmacy research.
- Experimental studies are often unfeasible in this field.
- Observational research has identified risk factors for older persons taking multiple medications.
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Description
This quiz assesses understanding of polypharmacy's impact on older adults, including the link between multiple medications and frailty.
