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Questions and Answers
Which red cell type appears markedly spherical and is associated with hereditary spherocytosis?
Which red cell type appears markedly spherical and is associated with hereditary spherocytosis?
- Acanthocyte
- Stomatocyte
- Spherocyte (correct)
- Xerocyte
What is a characteristic feature of an acanthocyte’s surface?
What is a characteristic feature of an acanthocyte’s surface?
- Flat and smooth
- Slit-like central pallor
- Uniformly round
- Irregularly spiculated (correct)
Which condition is NOT associated with stomatocytes?
Which condition is NOT associated with stomatocytes?
- Cirrhosis of the liver (correct)
- Alcoholism
- Severe liver disease
- Rh Deficiency Syndrome
Which description best fits a xerocyte?
Which description best fits a xerocyte?
What is the primary issue regarding the identification of spherocytes in blood smears?
What is the primary issue regarding the identification of spherocytes in blood smears?
Flashcards
Spherocyte
Spherocyte
Almost spherical red blood cell, lacking central pallor.
Spherocyte Associated Conditions
Spherocyte Associated Conditions
Hereditary spherocytosis, autoimmune hemolytic anemia, burns, ABO HDN, and following transfusion of stored blood.
Stomatocyte
Stomatocyte
Elongated red blood cell with a slit-like central pallor. Sometimes considered an artifact.
Stomatocyte Associated Conditions
Stomatocyte Associated Conditions
Rh Deficiency Syndrome, Alcoholism, Electrolyte imbalance, Severe liver diseases, Hereditary Stomatocytosis(Overhydrated/Dehydrated).
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Acanthocyte
Acanthocyte
Red blood cell with irregularly spiculated surface, uneven projections.
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Acanthocyte Associated Conditions
Acanthocyte Associated Conditions
Abetalipoproteinemia, McLeod Syndrome, Pyruvate kinase deficiency, Hepatic hemangioma, Neonatal hepatitis, After heparin administration, Postsplenectomy, Cirrhosis of the liver with associated hemolytic anemia, TAR Syndrome.
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Xerocyte
Xerocyte
A dehydrated form of a stomatocyte; appears to have puddled at one end.
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Xerocyte Associated Conditions
Xerocyte Associated Conditions
Most common form of stomatocytosis.
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Red Blood Cell (RBC) Types
Red Blood Cell (RBC) Types
Different forms of red blood cells with varying shapes and characteristics.
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Poikilocytosis
- Increased number of red blood cells with variations in shape
Red Blood Cell Types
Spherocyte
- Almost spherical shape
- Lacks central pallor
- Associated with:
- Hereditary spherocytosis
- Autoimmune hemolytic anemia
- Burns
- ABO blood type incompatibility
- Blood transfusions of stored blood
Stomatocyte
- Elongated red blood cells with a slit-like central pallor
- May be an artifact
- Associated with:
- Rh deficiency syndrome
- Alcoholism
- Electrolyte imbalances
- Severe liver disease
- Overhydrated hereditary stomatocytosis
- Dehydrated hereditary stomatocytosis (also known as hereditary stomatocytosis)
Acanthocyte
- Red blood cells with irregularly spiculated surface
- Associated with:
- Abetalipoproteinemia (also known as hereditary acanthocytosis)
- McLeod syndrome
- Pyruvate kinase deficiency
- Hepatic hemangioma
- Neonatal hepatitis
- After heparin administration
- Post-splenectomy
- Liver cirrhosis with associated hemolytic anemia
- TAR syndrome
Xerocyte
- A dehydrated form of a stomatocyte
- Appears to have puddled at one end (half-light, half-dark)
- Most common form of stomatocytosis
- Characterized by the presence of xerocytes
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