Podcast
Questions and Answers
Which red cell type appears markedly spherical and is associated with hereditary spherocytosis?
Which red cell type appears markedly spherical and is associated with hereditary spherocytosis?
What is a characteristic feature of an acanthocyte’s surface?
What is a characteristic feature of an acanthocyte’s surface?
Which condition is NOT associated with stomatocytes?
Which condition is NOT associated with stomatocytes?
Which description best fits a xerocyte?
Which description best fits a xerocyte?
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What is the primary issue regarding the identification of spherocytes in blood smears?
What is the primary issue regarding the identification of spherocytes in blood smears?
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Study Notes
Poikilocytosis
- Increased number of red blood cells with variations in shape
Red Blood Cell Types
Spherocyte
- Almost spherical shape
- Lacks central pallor
- Associated with:
- Hereditary spherocytosis
- Autoimmune hemolytic anemia
- Burns
- ABO blood type incompatibility
- Blood transfusions of stored blood
Stomatocyte
- Elongated red blood cells with a slit-like central pallor
- May be an artifact
- Associated with:
- Rh deficiency syndrome
- Alcoholism
- Electrolyte imbalances
- Severe liver disease
- Overhydrated hereditary stomatocytosis
- Dehydrated hereditary stomatocytosis (also known as hereditary stomatocytosis)
Acanthocyte
- Red blood cells with irregularly spiculated surface
- Associated with:
- Abetalipoproteinemia (also known as hereditary acanthocytosis)
- McLeod syndrome
- Pyruvate kinase deficiency
- Hepatic hemangioma
- Neonatal hepatitis
- After heparin administration
- Post-splenectomy
- Liver cirrhosis with associated hemolytic anemia
- TAR syndrome
Xerocyte
- A dehydrated form of a stomatocyte
- Appears to have puddled at one end (half-light, half-dark)
- Most common form of stomatocytosis
- Characterized by the presence of xerocytes
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Description
This quiz covers the variations in red blood cell shapes and their associations with various medical conditions. Test your knowledge on spherocytes, stomatocytes, and acanthocytes, and understand their clinical significance in hematology.
