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Questions and Answers
MACROCYTE - RBC measuring more than 9 micra in ______
MACROCYTE - RBC measuring more than 9 micra in ______
diameter
MEGALOCYTE - RBC measuring from 12-21 micra in ______
MEGALOCYTE - RBC measuring from 12-21 micra in ______
diameter
ACANTHOCYTE (THORN CELL, SPUR CELL) - Irreversibly thorny, rounded RBC with irregularly arranged 5-10 spicules of various lengths, some of which are bent at their tips. - Their presence indicates permanent ______.
ACANTHOCYTE (THORN CELL, SPUR CELL) - Irreversibly thorny, rounded RBC with irregularly arranged 5-10 spicules of various lengths, some of which are bent at their tips. - Their presence indicates permanent ______.
damage
ECHINOCYTE (CRENATED RED BLOOD CELL) - Has 10-30 short and blunt spicule that are evenly distributed over the surface of the RBC. - Produce when blood is allowed to stand when RBCs are exposed to lytic agents or when RBCs are placed in ______ solutions.
ECHINOCYTE (CRENATED RED BLOOD CELL) - Has 10-30 short and blunt spicule that are evenly distributed over the surface of the RBC. - Produce when blood is allowed to stand when RBCs are exposed to lytic agents or when RBCs are placed in ______ solutions.
ANISOCYTOSIS Variation in ______ of red blood cells (a sign of regeneration).
ANISOCYTOSIS Variation in ______ of red blood cells (a sign of regeneration).
SICKLE CELL (DREPANOCYTE, MENISCOCYTE) - Cresent – shaped RBC. - Elongated, Drawn-out, slightly curved cell with pointed ends that resemble a ______ blade.
SICKLE CELL (DREPANOCYTE, MENISCOCYTE) - Cresent – shaped RBC. - Elongated, Drawn-out, slightly curved cell with pointed ends that resemble a ______ blade.
SPHEROCYTE - Spherical-shape RBC with diminished diameter sometimes reduces to 4 micra (microspherocyte), and has a central thickened portion instead of the normal ______.
SPHEROCYTE - Spherical-shape RBC with diminished diameter sometimes reduces to 4 micra (microspherocyte), and has a central thickened portion instead of the normal ______.
STOMATOCYTE (MOUTH CELL) - Morphologically abnormal RBC with a slit-like clear central area. - Exhibits abnormally increased Osmotic Fragility & increased Autohemolysis at 37 to 40 degrees ______.
STOMATOCYTE (MOUTH CELL) - Morphologically abnormal RBC with a slit-like clear central area. - Exhibits abnormally increased Osmotic Fragility & increased Autohemolysis at 37 to 40 degrees ______.
SCHISTOCYTE - Fragmenting/disintegrating RBC usually seen In Hemolytic Anemia, Severe Burns & Diffuse Intravascular Coagulation (DIC) Syndrome. 3. ELLIPTOCYTE (OVALOCYTE) - Elliptical or oval-shaped red cells. - Usually seen in pernicious anemia and in anemias associated with malignant ______.
SCHISTOCYTE - Fragmenting/disintegrating RBC usually seen In Hemolytic Anemia, Severe Burns & Diffuse Intravascular Coagulation (DIC) Syndrome. 3. ELLIPTOCYTE (OVALOCYTE) - Elliptical or oval-shaped red cells. - Usually seen in pernicious anemia and in anemias associated with malignant ______.
BLISTER CELL - RBC with Single or Multiple Vacuoles or markedly thinned areas at the periphery. - Result of trauma to RBCs during their passage through partially obstructed blood ______.
BLISTER CELL - RBC with Single or Multiple Vacuoles or markedly thinned areas at the periphery. - Result of trauma to RBCs during their passage through partially obstructed blood ______.
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Study Notes
Abnormal Red Blood Cells
- Macrocyes: RBCs measuring more than 9 micra in diameter
- Megalocytes: RBCs measuring from 12-21 micra in diameter
Acanthocyte (Thorn Cell, Spur Cell)
- Irreversibly thorny, rounded RBC with irregularly arranged 5-10 spicules of various lengths, some bent at their tips
- Indicates permanent brain injury or neurological disorders
Echinocyte (Crenated Red Blood Cell)
- Has 10-30 short and blunt spicules evenly distributed over the surface of the RBC
- Produced when blood is allowed to stand, or when RBCs are exposed to lytic agents or placed in hypotonic solutions
Anisocytosis
- Variation in size of red blood cells, a sign of regeneration
Sickle Cell (Drepanocyte, Meniscocyte)
- Crescent-shaped RBC
- Elongated, drawn-out, slightly curved cell with pointed ends, resembling a scimitar blade
Spherocyte
- Spherical-shaped RBC with diminished diameter, sometimes reduced to 4 micra (microspherocyte)
- Has a central thickened portion instead of the normal biconcave disk shape
Stomatocyte (Mouth Cell)
- Morphologically abnormal RBC with a slit-like clear central area
- Exhibits abnormally increased osmotic fragility and increased autohemolysis at 37 to 40 degrees Celsius
Schistocyte
- Fragmenting/disintegrating RBC, usually seen in Hemolytic Anemia, Severe Burns, and Diffuse Intravascular Coagulation (DIC) Syndrome
Elliptocyte (Ovalocyte)
- Elliptical or oval-shaped red cells
- Usually seen in pernicious anemia and in anemias associated with malignant neoplasms
Blister Cell
- RBC with single or multiple vacuoles or markedly thinned areas at the periphery
- Result of trauma to RBCs during their passage through partially obstructed blood vessels
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