10 Questions
MACROCYTE - RBC measuring more than 9 micra in ______
diameter
MEGALOCYTE - RBC measuring from 12-21 micra in ______
diameter
ACANTHOCYTE (THORN CELL, SPUR CELL) - Irreversibly thorny, rounded RBC with irregularly arranged 5-10 spicules of various lengths, some of which are bent at their tips. - Their presence indicates permanent ______.
damage
ECHINOCYTE (CRENATED RED BLOOD CELL) - Has 10-30 short and blunt spicule that are evenly distributed over the surface of the RBC. - Produce when blood is allowed to stand when RBCs are exposed to lytic agents or when RBCs are placed in ______ solutions.
hypertonic
ANISOCYTOSIS Variation in ______ of red blood cells (a sign of regeneration).
size
SICKLE CELL (DREPANOCYTE, MENISCOCYTE) - Cresent – shaped RBC. - Elongated, Drawn-out, slightly curved cell with pointed ends that resemble a ______ blade.
sickle
SPHEROCYTE - Spherical-shape RBC with diminished diameter sometimes reduces to 4 micra (microspherocyte), and has a central thickened portion instead of the normal ______.
pallor
STOMATOCYTE (MOUTH CELL) - Morphologically abnormal RBC with a slit-like clear central area. - Exhibits abnormally increased Osmotic Fragility & increased Autohemolysis at 37 to 40 degrees ______.
celsius
SCHISTOCYTE - Fragmenting/disintegrating RBC usually seen In Hemolytic Anemia, Severe Burns & Diffuse Intravascular Coagulation (DIC) Syndrome. 3. ELLIPTOCYTE (OVALOCYTE) - Elliptical or oval-shaped red cells. - Usually seen in pernicious anemia and in anemias associated with malignant ______.
lesions
BLISTER CELL - RBC with Single or Multiple Vacuoles or markedly thinned areas at the periphery. - Result of trauma to RBCs during their passage through partially obstructed blood ______.
vessel
Study Notes
Abnormal Red Blood Cells
- Macrocyes: RBCs measuring more than 9 micra in diameter
- Megalocytes: RBCs measuring from 12-21 micra in diameter
Acanthocyte (Thorn Cell, Spur Cell)
- Irreversibly thorny, rounded RBC with irregularly arranged 5-10 spicules of various lengths, some bent at their tips
- Indicates permanent brain injury or neurological disorders
Echinocyte (Crenated Red Blood Cell)
- Has 10-30 short and blunt spicules evenly distributed over the surface of the RBC
- Produced when blood is allowed to stand, or when RBCs are exposed to lytic agents or placed in hypotonic solutions
Anisocytosis
- Variation in size of red blood cells, a sign of regeneration
Sickle Cell (Drepanocyte, Meniscocyte)
- Crescent-shaped RBC
- Elongated, drawn-out, slightly curved cell with pointed ends, resembling a scimitar blade
Spherocyte
- Spherical-shaped RBC with diminished diameter, sometimes reduced to 4 micra (microspherocyte)
- Has a central thickened portion instead of the normal biconcave disk shape
Stomatocyte (Mouth Cell)
- Morphologically abnormal RBC with a slit-like clear central area
- Exhibits abnormally increased osmotic fragility and increased autohemolysis at 37 to 40 degrees Celsius
Schistocyte
- Fragmenting/disintegrating RBC, usually seen in Hemolytic Anemia, Severe Burns, and Diffuse Intravascular Coagulation (DIC) Syndrome
Elliptocyte (Ovalocyte)
- Elliptical or oval-shaped red cells
- Usually seen in pernicious anemia and in anemias associated with malignant neoplasms
Blister Cell
- RBC with single or multiple vacuoles or markedly thinned areas at the periphery
- Result of trauma to RBCs during their passage through partially obstructed blood vessels
Test your knowledge about red blood cell anomalies including anisocytosis and poikilocytosis. Learn about the variations in size of red blood cells and their possible causes, such as iron deficiency or lack of necessary materials for cell development.
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