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Questions and Answers
What is the classification of Plavix?
What is the classification of Plavix?
What is the mechanism of action (MOA) of Plavix?
What is the mechanism of action (MOA) of Plavix?
Clopidogrel is an inhibitor of platelet activation and aggregation through the irreversible binding of its active metabolite to the P2Y12 class of ADP receptors on each platelet.
Which conditions is Plavix indicated for?
Which conditions is Plavix indicated for?
What are the other names for Plavix?
What are the other names for Plavix?
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Common side effects of Plavix include _________.
Common side effects of Plavix include _________.
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What is a contraindication for using Plavix?
What is a contraindication for using Plavix?
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What special information should be considered for AMI patients taking Plavix?
What special information should be considered for AMI patients taking Plavix?
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How is Plavix typically administered?
How is Plavix typically administered?
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Study Notes
Plavix Overview
- Plavix is classified as a platelet inhibitor, primarily used to reduce the risk of blood clots.
Mechanism of Action (MOA)
- Clopidogrel, the active ingredient in Plavix, irreversibly binds to P2Y12 ADP receptors on platelets.
- This binding inhibits platelet activation and aggregation, essential for blood clot formation.
Indications for Use
- Indicated for treatment in acute myocardial infarction (AMI) patients.
- Effective in both STEMI (ST-Elevation Myocardial Infarction) and NSTEMI (Non-ST-Elevation Myocardial Infarction) cases.
- Used for patients with recent cerebrovascular accidents (CVA) and peripheral arterial disease.
Alternative Names
- Commonly known as Clopidogrel bisulfate or simply Clopidogrel.
Side Effects
- Potential side effects include various forms of bleeding, which can be fatal.
- Other possible adverse effects: fever, liver issues, allergic reactions, confusion, bronchospasms, elevated creatinine levels, rashes, and hypotension.
Contraindications
- Should not be used in patients with active bleeding conditions, such as peptic ulcers or intracranial hemorrhage.
- Contraindicated in individuals with known hypersensitivity to Clopidogrel.
Special Considerations
- Ask AMI patients about history of active bleeding, recent strokes, and allergies to Plavix, ASA, or eggs.
- Avoid drug interactions with Omeprazole (Prilosec) and monitor use with NSAIDs and Warfarin due to bleeding risk.
- Pregnancy category B; consult with an emergency medicine doctor for nursing mothers.
- Safety and efficacy in pediatric patients have not been established.
Dosage and Administration
- Administered orally, with a common initial dose of 600 mg as per physician orders.
- Available in tablet forms of 75 mg and 300 mg.
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Description
This quiz focuses on the essential flashcards related to Plavix, highlighting its classification as a platelet inhibitor and the mechanism of action (MOA) of clopidogrel. Learn about the drug's indications and vital functions in preventing clot formation. Perfect for students and healthcare professionals looking to reinforce their knowledge on pharmacology.
