Plasma Proteins and Enzymes in Diagnostic Medicine
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Questions and Answers

Which proteins are synthesized in the liver, with the exception of immunoglobulins?

  • Plasma Proteins (correct)
  • Serum Electrophoresis
  • Anticoagulants
  • Acute Phase Proteins
  • Which substances do Citrate, Oxalate, and EDTA bind to?

  • Divalent cations (correct)
  • Plasma proteins
  • Immunoglobulins
  • Fatty acids
  • Which proteins are responsible for maintaining oncotic pressure and transporting substances like fatty acids and bilirubin?

  • γ-Globulins
  • Albumin (correct)
  • α1-Globulins
  • β2-Globulins
  • Which proteins are part of the major bands in electrophoresis?

    <p>Immunoglobulins and α1-Antitrypsin</p> Signup and view all the answers

    Which type of proteins are mostly glycoproteins?

    <p>Plasma Proteins</p> Signup and view all the answers

    Which proteins in plasma can be used for the diagnosis of different diseases?

    <p>Albumin and globulin</p> Signup and view all the answers

    What is the main function of colloid osmotic pressure created by plasma proteins?

    <p>To prevent edema</p> Signup and view all the answers

    Which enzymes are commonly used in the diagnosis of organ diseases?

    <p>Amylase and lipase</p> Signup and view all the answers

    What is the primary purpose of using enzymes in the diagnosis of organ diseases?

    <p>To detect liver damage</p> Signup and view all the answers

    How do plasma proteins contribute to the diagnosis of diseases?

    <p>By indicating abnormalities through their levels or changes</p> Signup and view all the answers

    Which enzyme is responsible for the hydrolytic cleavage of various esters of choline?

    <p>Plasma cholinesterase (BuChE)</p> Signup and view all the answers

    In which tissues is plasma cholinesterase (BuChE) found?

    <p>Plasma and liver</p> Signup and view all the answers

    What is the principal location of acetylcholinesterase (ACHE)?

    <p>Nervous tissue and erythrocytes</p> Signup and view all the answers

    What inhibits the activity of both BuChE and ACHE?

    <p>Organophosphates (OP’s)</p> Signup and view all the answers

    What are the clinical symptoms arising from when there is a build-up of acetylcholine?

    <p>Ingestion of organophosphates (OP’s)</p> Signup and view all the answers

    Study Notes

    Proteins Synthesized in the Liver

    • All proteins are synthesized in the liver, except for immunoglobulins.

    Binding Properties of Citrate, Oxalate, and EDTA

    • Citrate, Oxalate, and EDTA bind to calcium ions.

    Proteins Responsible for Oncotic Pressure and Transport

    • Albumin is responsible for maintaining oncotic pressure and transporting substances like fatty acids and bilirubin.

    Major Bands in Electrophoresis

    • Albumin and globulins are part of the major bands in electrophoresis.

    Glycoproteins

    • Most globulins are glycoproteins.

    Diagnostic Proteins in Plasma

    • Various proteins in plasma can be used for the diagnosis of different diseases, including albumin, globulins, and enzymes.

    Colloid Osmotic Pressure

    • The main function of colloid osmotic pressure created by plasma proteins is to maintain blood volume and prevent edema.

    Enzymes in Diagnosis of Organ Diseases

    • Enzymes commonly used in the diagnosis of organ diseases include lactate dehydrogenase (LDH), aspartate transaminase (AST), and alanine transaminase (ALT).

    Purpose of Enzymes in Diagnosis

    • The primary purpose of using enzymes in the diagnosis of organ diseases is to detect tissue damage or injury.

    Contribution of Plasma Proteins to Diagnosis

    • Plasma proteins contribute to the diagnosis of diseases by serving as biomarkers for different conditions.

    Plasma Cholinesterase (BuChE)

    • Plasma cholinesterase (BuChE) is responsible for the hydrolytic cleavage of various esters of choline.
    • BuChE is found in the liver, nerve tissue, and plasma.

    Acetylcholinesterase (ACHE)

    • The principal location of acetylcholinesterase (ACHE) is in the synapses of neurons.
    • ACHE is responsible for the breakdown of acetylcholine.

    Inhibitors of BuChE and ACHE

    • The activity of both BuChE and ACHE can be inhibited by organophosphates.

    Clinical Symptoms of Acetylcholine Build-up

    • The clinical symptoms arising from a build-up of acetylcholine include muscle weakness, fasciculations, and paralysis.

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    W1 Plasma Proteins (Damuni) PDF

    Description

    Test your knowledge about plasma proteins and enzymes used as diagnostic tools in medicine with this quiz based on the principles of medical biochemistry. Learn to identify the proteins and enzymes used for diagnosing different diseases, connect clinical symptoms with laboratory tests, and make accurate diagnoses.

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