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Pituitary Adenoma Symptoms and Characteristics

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Pituitary Adenoma Symptoms and Characteristics

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Questions and Answers

What is the second most common age-related neurodegenerative disease?

Parkinson's disease (correct)

Multiple sclerosis

Amyotrophic lateral sclerosis

Huntington's disease

Who first described the cardinal clinical features of Parkinson's disease?

Jean-Martin Charcot

Alois Alzheimer

Sir William Osler

James Parkinson (correct)

Approximately how many people worldwide are estimated to have Parkinson's disease?

20 million

10 million

2 million

5 million (correct)

What is the mean age of onset for Parkinson's disease?

60 years Signup and view all the answers

Which of the following is NOT listed as a cardinal clinical feature of Parkinson's disease?

Seizures Signup and view all the answers

How is the lifetime risk of Parkinson's disease different between men and women?

Higher in men than women Signup and view all the answers

What is the hallmark pathological feature of Parkinson's disease?

Degeneration of dopaminergic neurons in the substantia nigra pars compacta Signup and view all the answers

What are the proteinaceous inclusions found in Parkinson's disease called?

Lewy bodies and Lewy neurites Signup and view all the answers

Which brain regions are affected by non-dopaminergic neurodegeneration in Parkinson's disease?

Nucleus basalis of Meynert, locus coeruleus, and raphe nuclei Signup and view all the answers

According to the Braak staging hypothesis, where does Lewy pathology begin in Parkinson's disease?

Peripheral autonomic nervous system, olfactory system, and lower brainstem Signup and view all the answers

Which of the following is considered an early premotor symptom of Parkinson's disease?

Anosmia (loss of smell) Signup and view all the answers

Why is it important to accurately define a premotor stage of Parkinson's disease?

To initiate disease-modifying treatment at the earliest possible stage Signup and view all the answers