Phytocannabinoids: Natural Cannabinoids in Plants
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Questions and Answers

What is the effect of CBD-V on pain?

  • Relieves headaches
  • Relieves neuropathic pain (correct)
  • Relieves migraines
  • Relieves muscle pain
  • What is the role of CBG in the cannabis plant?

  • It is the final product of cannabinoid synthesis
  • It is a breakdown product of CBD
  • It is the precursor to THC and CBD (correct)
  • It is formed when THC oxidizes with time or light
  • What is NOT an effect of CBG?

  • Intoxicating (correct)
  • Antibacterial
  • Neuroprotectant
  • Anticancer
  • What happens to THC as it ages?

    <p>It turns into CBN</p> Signup and view all the answers

    What is a effect of CBN?

    <p>Causes drowsiness</p> Signup and view all the answers

    What is the difference between Δ-8-THC and THC?

    <p>Δ-8-THC is a breakdown product of THC</p> Signup and view all the answers

    What is a characteristic of CBD-V?

    <p>It is not intoxicating</p> Signup and view all the answers

    What is a fun fact about CBG?

    <p>It is found in higher amounts in hemp</p> Signup and view all the answers

    What is the term used to describe cannabinoids that occur naturally in plants?

    <p>Phytocannabinoids</p> Signup and view all the answers

    What is the primary function of cannabinoids, regardless of their source?

    <p>To act upon the Endocannabinoid System</p> Signup and view all the answers

    What is the difference between psychoactive and psychotropic?

    <p>Psychoactive means it has an effect on the brain, while psychotropic means it has a high effect on the brain</p> Signup and view all the answers

    What is the effect of Δ-9-THC on the brain?

    <p>It produces a psychoactive effect</p> Signup and view all the answers

    What is one of the benefits of consuming Δ-9-THC with a high-fat diet?

    <p>It increases the absorption of Δ-9-THC</p> Signup and view all the answers

    What happens to Δ-9-THC when it is consumed?

    <p>It is stored in fatty tissue</p> Signup and view all the answers

    What is the result of first-pass metabolism in the liver for Δ-9-THC?

    <p>It is converted into 11-hydroxy-THC</p> Signup and view all the answers

    What is one of the benefits of finding the right cannabinoid profile for a patient?

    <p>It can lead to a substantial improvement in their condition</p> Signup and view all the answers

    What is a characteristic of edibles that makes them 'feel stronger' and last longer?

    <p>They bypass the first-pass effect of the liver</p> Signup and view all the answers

    What is the primary mechanism by which CBD affects the body?

    <p>It inhibits the breakdown of brain-produced endocannabinoids</p> Signup and view all the answers

    Which of the following effects is NOT associated with CBD?

    <p>Intoxication</p> Signup and view all the answers

    What happens to CBD-A when heated?

    <p>It loses its acid group and becomes CBD</p> Signup and view all the answers

    What is the primary difference between CBD and CBD-A?

    <p>CBD-A is found in RAW cannabis</p> Signup and view all the answers

    What is the effect of CBD on THC absorption?

    <p>It does not affect THC absorption</p> Signup and view all the answers

    What is the primary route of excretion for CBD?

    <p>Feces, with some excretion through urine</p> Signup and view all the answers

    What is the effect of CBD on appetite?

    <p>It stimulates appetite</p> Signup and view all the answers

    What is one of the effects of Δ-8-THC?

    <p>Relieves pain</p> Signup and view all the answers

    How is delta-8 THC typically manufactured?

    <p>From hemp-derived cannabidiol</p> Signup and view all the answers

    What is THC-A?

    <p>An acidic precursor to THC</p> Signup and view all the answers

    What is one of the effects of THC-A?

    <p>Anticonvulsant</p> Signup and view all the answers

    What is THC-V?

    <p>A non-psychoactive cannabinoid</p> Signup and view all the answers

    What is one of the effects of THC-V?

    <p>Appetite suppressant</p> Signup and view all the answers

    What is a potential use of THC-V?

    <p>Weight and diabetes management</p> Signup and view all the answers

    Which strain of cannabis is known to contain THC-V?

    <p>Durban Poison</p> Signup and view all the answers

    Study Notes

    Phytocannabinoids

    • Phytocannabinoids are cannabinoids that naturally occur in plants.
    • They act upon the Endocannabinoid System, binding to CB1 and CB2 receptors.
    • Some phytocannabinoids produce a psychoactive effect, while others do not.

    Δ-9-THC (THC)

    • The most known and prominent cannabinoid, producing a psychoactive effect.
    • Effects: "gets you high", pain relief, anti-nausea, anti-anxiety, helps with spasticity, sleep, and mood elevation.
    • Also has anti-cancer, anti-inflammatory, antioxidant, and neuroprotectant properties.
    • Fun facts: incomplete absorption in the lungs, greater bioavailability with a high-fat diet, stored in fatty tissue, and crosses the blood-brain barrier.

    CBD (Cannabidiol)

    • The second most commonly known cannabinoid, known for not producing a psychoactive effect.
    • Effects: inhibition of GI activity, anti-inflammatory, pain relief, anti-seizure, anti-anxiety, mood elevation, and antibacterial properties.
    • Also has anti-cancer, antioxidant, antipsychotic, and neuroprotectant properties.
    • Fun facts: not intoxicating, no tolerance or withdrawal, alerting effects in lower doses, and can be used to treat THC withdrawal.

    CBD-A (Cannabidiolic Acid)

    • The acidic state of CBD in the cannabis plant, before combustion or vaporization.
    • Effects: anti-anxiety, anti-depressant, anti-inflammatory, potential anti-seizure, and pain relief.
    • Fun facts: not intoxicating, found in RAW cannabis, and more potent than CBD for anti-nausea effects.

    CBD-V (Cannabidivarin)

    • Similar to CBD, non-psychoactive, and currently being developed as a synthetic drug.
    • Effects: anti-convulsant and relieves neuropathic pain.
    • Fun facts: not intoxicating, may help in Rett syndrome, and currently being developed as a synthetic drug.

    CBG (Cannabigerol)

    • The "godmother of all cannabinoids", the first cannabinoid created in the cannabis plant.
    • Effects: antibacterial, anti-cancer, antidepressant, anti-inflammatory, antioxidant, and neuroprotectant properties.
    • Fun facts: not intoxicating, found in higher amounts in hemp, and may block anti-nausea effects of CBD.

    CBN (Cannabinol)

    • Forms when THC oxidizes with time or light, making you tired.
    • Effects: antibacterial, anticonvulsant, promotes bone growth, and relieves pain.
    • Fun facts: a breakdown product of THC, increases as THC degrades over time, and not present in freshly cut flowers.

    Δ-8-THC (Delta-8)

    • A recent phenomenon in the cannabis arena, known for its potential THC "high" without the failed drug test.
    • Effects: anti-anxiety, anti-cancer, neuroprotectant, and relieves pain.
    • Fun facts: conflicting research on intoxicating effects, concentrated amounts are typically manufactured from hemp-derived CBD.

    THC-A (Delta-9-tetrahydrocannabinolic Acid)

    • The acidic precursor to THC, non-intoxicating in its natural state.
    • Effects: anticonvulsant, anti-inflammatory, antispasmodic, and neuroprotectant properties.
    • Fun facts: not intoxicating, the main compound in raw cannabis flowers, and converts to THC with heat.

    THC-V (Delta-9-tetrahydrocannabivarin)

    • Found in sativa-leaning varieties, non-psychoactive, and has potential for weight and diabetes management.
    • Effects: anti-cancer, anticonvulsant, anti-inflammatory, antioxidant, and neuroprotectant properties.
    • Fun facts: not intoxicating in low doses, may be beneficial for Parkinson's disease, and known to suppress appetite.

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