Physiology Quiz on Fluid Dynamics and Infusions

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Questions and Answers

What is the effect of infusing 2 liters of a hypertonic 3.0% NaCl solution into the extracellular fluid?

  • Results in no change to fluid volumes
  • Increases extracellular fluid volume by more than 5 liters (correct)
  • Increases intracellular fluid volume by 3 liters
  • Decreases extracellular fluid osmolarity to below 280 mOsm/L

What is the initial osmolarity of plasma before the infusion of hypertonic saline?

  • 300 mOsm/L
  • 260 mOsm/L
  • 290 mOsm/L
  • 280 mOsm/L (correct)

How many miliosmoles are added to the extracellular fluid after the infusion of 2 liters of hypertonic saline?

  • 2052 miliosmoles (correct)
  • 1026 miliosmoles
  • 1500 miliosmoles
  • 513 miliosmoles

What tends to occur after glucose solutions are administered?

<p>They often leave an excess of water after metabolism (D)</p> Signup and view all the answers

What is the effect of hypertonic saline on intracellular fluid volume immediately after infusion?

<p>Decreases intracellular fluid volume (A)</p> Signup and view all the answers

Why are glucose solutions typically administered at isotonic concentrations or slowly?

<p>To prevent osmotic imbalance in body fluids (A)</p> Signup and view all the answers

What happens to the concentration of cations in plasma compared to interstitial fluid due to the Donnan effect?

<p>It is slightly greater in plasma. (B)</p> Signup and view all the answers

What is the effect of administering hypertonic saline on the intracellular fluid after osmotic equilibrium is established?

<p>Decreases the intracellular fluid significantly (C)</p> Signup and view all the answers

What is a significant consequence of extensive burns regarding fluid loss?

<p>Water loss can reach 3-5 L/day. (A)</p> Signup and view all the answers

What must an indicator do for the indicator-dilution method to accurately measure fluid volumes?

<p>It must disperse evenly throughout the compartment being measured. (D)</p> Signup and view all the answers

What happens to the kidneys after excess water remains in the body following nutrient metabolism?

<p>They excrete very dilute urine (C)</p> Signup and view all the answers

Which statement about negatively charged ions in plasma and interstitial fluid is true?

<p>They tend to have a higher concentration in interstitial fluid. (B)</p> Signup and view all the answers

What role do negatively charged plasma proteins play regarding cations?

<p>They bind cations and retain them in plasma. (B)</p> Signup and view all the answers

What is a characteristic of the ionic composition of plasma compared to interstitial fluid?

<p>Ionic composition is similar overall. (B)</p> Signup and view all the answers

Which requirement is NOT necessary for the indicator-dilution principle to work effectively?

<p>The indicator should be metabolized. (A)</p> Signup and view all the answers

Which of the following is NOT true regarding the constituents of extracellular and intracellular fluids?

<p>Anions are more concentrated in plasma than interstitial fluid. (C)</p> Signup and view all the answers

What happens to the total mass of a substance after it is dispensed in a fluid compartment?

<p>It remains the same as the injected mass. (D)</p> Signup and view all the answers

What primarily influences the distribution of extracellular fluid between plasma and interstitial spaces?

<p>The balance of hydrostatic and colloid osmotic forces. (B)</p> Signup and view all the answers

How does osmosis occur across a selectively permeable membrane?

<p>From a region of high to low water concentration. (A)</p> Signup and view all the answers

What distinguishes osmolarity from osmolality?

<p>Osmolarity is per liter of solution, while osmolality is per kilogram of water. (C)</p> Signup and view all the answers

How many osmoles are produced from one mole of NaCl in solution?

<p>Two osmoles. (D)</p> Signup and view all the answers

According to van't Hoff's law, what is the osmotic pressure based on?

<p>The assumption that the cell membrane is impermeable to the solute. (C)</p> Signup and view all the answers

What is the osmolar concentration of a solution containing 1 mole of glucose per liter?

<p>1 osm/L. (A)</p> Signup and view all the answers

What amount of NaCl is present in a 0.9% NaCl solution per liter?

<p>9 g. (C)</p> Signup and view all the answers

What is the osmolarity of a NaCl solution with a molarity of 0.154 mol/L?

<p>0.308 osm/L (A)</p> Signup and view all the answers

What is the effect of a concentration gradient of impermeant solutes on osmotic pressure across the cell membrane?

<p>It exerts a pressure of 19.3 mm Hg per milliosmole. (D)</p> Signup and view all the answers

What can cause large changes in cell volume due to osmotic forces?

<p>Changes in impermeant solute concentrations in extracellular fluid. (C)</p> Signup and view all the answers

At what osmolarity does the intracellular fluid lie when the membrane is exposed to pure water?

<p>282 mOsm/L (C)</p> Signup and view all the answers

What is the potential osmotic pressure of a solution with an osmolarity of 308 mOsm/L?

<p>5944 mm Hg (D)</p> Signup and view all the answers

Which of the following is NOT a factor that causes changes in extracellular and intracellular volumes?

<p>Increased exercise (D)</p> Signup and view all the answers

How often do the osmolarities of intracellular and extracellular fluids remain equal?

<p>Almost exactly equal except for a few minutes after changes. (A)</p> Signup and view all the answers

Which statement is true regarding cell membranes and solutes?

<p>Many solutes cannot permeate cell membranes, maintaining osmole constancy. (C)</p> Signup and view all the answers

What is a potential consequence of acute hyponatremia that affects brain function?

<p>Brain cell edema (D)</p> Signup and view all the answers

What is the threshold plasma sodium concentration below which brain swelling may lead to severe symptoms?

<p>115 to 120 mmol/L (A)</p> Signup and view all the answers

Which condition is commonly associated with cell shrinkage?

<p>Hypernatremia (B)</p> Signup and view all the answers

What factor can increase capillary filtration rate?

<p>Increased capillary hydrostatic pressure (B)</p> Signup and view all the answers

What condition may lead to severe hypernatremia in infants?

<p>Impaired thirst response (B)</p> Signup and view all the answers

What is one of the primary causes of intracellular edema?

<p>Hyponatremia (B)</p> Signup and view all the answers

What is edema primarily characterized by?

<p>Excess fluid in tissues (D)</p> Signup and view all the answers

Which factor is NOT a cause of extracellular edema?

<p>Increased sodium concentration (A)</p> Signup and view all the answers

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