Physiology Quiz on Fluid Dynamics and Infusions
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Questions and Answers

What is the effect of infusing 2 liters of a hypertonic 3.0% NaCl solution into the extracellular fluid?

  • Results in no change to fluid volumes
  • Increases extracellular fluid volume by more than 5 liters (correct)
  • Increases intracellular fluid volume by 3 liters
  • Decreases extracellular fluid osmolarity to below 280 mOsm/L
  • What is the initial osmolarity of plasma before the infusion of hypertonic saline?

  • 300 mOsm/L
  • 260 mOsm/L
  • 290 mOsm/L
  • 280 mOsm/L (correct)
  • How many miliosmoles are added to the extracellular fluid after the infusion of 2 liters of hypertonic saline?

  • 2052 miliosmoles (correct)
  • 1026 miliosmoles
  • 1500 miliosmoles
  • 513 miliosmoles
  • What tends to occur after glucose solutions are administered?

    <p>They often leave an excess of water after metabolism</p> Signup and view all the answers

    What is the effect of hypertonic saline on intracellular fluid volume immediately after infusion?

    <p>Decreases intracellular fluid volume</p> Signup and view all the answers

    Why are glucose solutions typically administered at isotonic concentrations or slowly?

    <p>To prevent osmotic imbalance in body fluids</p> Signup and view all the answers

    What happens to the concentration of cations in plasma compared to interstitial fluid due to the Donnan effect?

    <p>It is slightly greater in plasma.</p> Signup and view all the answers

    What is the effect of administering hypertonic saline on the intracellular fluid after osmotic equilibrium is established?

    <p>Decreases the intracellular fluid significantly</p> Signup and view all the answers

    What is a significant consequence of extensive burns regarding fluid loss?

    <p>Water loss can reach 3-5 L/day.</p> Signup and view all the answers

    What must an indicator do for the indicator-dilution method to accurately measure fluid volumes?

    <p>It must disperse evenly throughout the compartment being measured.</p> Signup and view all the answers

    What happens to the kidneys after excess water remains in the body following nutrient metabolism?

    <p>They excrete very dilute urine</p> Signup and view all the answers

    Which statement about negatively charged ions in plasma and interstitial fluid is true?

    <p>They tend to have a higher concentration in interstitial fluid.</p> Signup and view all the answers

    What role do negatively charged plasma proteins play regarding cations?

    <p>They bind cations and retain them in plasma.</p> Signup and view all the answers

    What is a characteristic of the ionic composition of plasma compared to interstitial fluid?

    <p>Ionic composition is similar overall.</p> Signup and view all the answers

    Which requirement is NOT necessary for the indicator-dilution principle to work effectively?

    <p>The indicator should be metabolized.</p> Signup and view all the answers

    Which of the following is NOT true regarding the constituents of extracellular and intracellular fluids?

    <p>Anions are more concentrated in plasma than interstitial fluid.</p> Signup and view all the answers

    What happens to the total mass of a substance after it is dispensed in a fluid compartment?

    <p>It remains the same as the injected mass.</p> Signup and view all the answers

    What primarily influences the distribution of extracellular fluid between plasma and interstitial spaces?

    <p>The balance of hydrostatic and colloid osmotic forces.</p> Signup and view all the answers

    How does osmosis occur across a selectively permeable membrane?

    <p>From a region of high to low water concentration.</p> Signup and view all the answers

    What distinguishes osmolarity from osmolality?

    <p>Osmolarity is per liter of solution, while osmolality is per kilogram of water.</p> Signup and view all the answers

    How many osmoles are produced from one mole of NaCl in solution?

    <p>Two osmoles.</p> Signup and view all the answers

    According to van't Hoff's law, what is the osmotic pressure based on?

    <p>The assumption that the cell membrane is impermeable to the solute.</p> Signup and view all the answers

    What is the osmolar concentration of a solution containing 1 mole of glucose per liter?

    <p>1 osm/L.</p> Signup and view all the answers

    What amount of NaCl is present in a 0.9% NaCl solution per liter?

    <p>9 g.</p> Signup and view all the answers

    What is the osmolarity of a NaCl solution with a molarity of 0.154 mol/L?

    <p>0.308 osm/L</p> Signup and view all the answers

    What is the effect of a concentration gradient of impermeant solutes on osmotic pressure across the cell membrane?

    <p>It exerts a pressure of 19.3 mm Hg per milliosmole.</p> Signup and view all the answers

    What can cause large changes in cell volume due to osmotic forces?

    <p>Changes in impermeant solute concentrations in extracellular fluid.</p> Signup and view all the answers

    At what osmolarity does the intracellular fluid lie when the membrane is exposed to pure water?

    <p>282 mOsm/L</p> Signup and view all the answers

    What is the potential osmotic pressure of a solution with an osmolarity of 308 mOsm/L?

    <p>5944 mm Hg</p> Signup and view all the answers

    Which of the following is NOT a factor that causes changes in extracellular and intracellular volumes?

    <p>Increased exercise</p> Signup and view all the answers

    How often do the osmolarities of intracellular and extracellular fluids remain equal?

    <p>Almost exactly equal except for a few minutes after changes.</p> Signup and view all the answers

    Which statement is true regarding cell membranes and solutes?

    <p>Many solutes cannot permeate cell membranes, maintaining osmole constancy.</p> Signup and view all the answers

    What is a potential consequence of acute hyponatremia that affects brain function?

    <p>Brain cell edema</p> Signup and view all the answers

    What is the threshold plasma sodium concentration below which brain swelling may lead to severe symptoms?

    <p>115 to 120 mmol/L</p> Signup and view all the answers

    Which condition is commonly associated with cell shrinkage?

    <p>Hypernatremia</p> Signup and view all the answers

    What factor can increase capillary filtration rate?

    <p>Increased capillary hydrostatic pressure</p> Signup and view all the answers

    What condition may lead to severe hypernatremia in infants?

    <p>Impaired thirst response</p> Signup and view all the answers

    What is one of the primary causes of intracellular edema?

    <p>Hyponatremia</p> Signup and view all the answers

    What is edema primarily characterized by?

    <p>Excess fluid in tissues</p> Signup and view all the answers

    Which factor is NOT a cause of extracellular edema?

    <p>Increased sodium concentration</p> Signup and view all the answers

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