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Questions and Answers
What is the chemical formula of uric acid?
What is the chemical formula of uric acid?
- C7H7N6O5
- C5H5N3O2
- C5H4N4O3 (correct)
- C6H6N5O4
What is the main organ where uric acid is produced?
What is the main organ where uric acid is produced?
- Brain
- Liver (correct)
- Heart
- Lung
What is the normal reference range of uric acid in male blood plasma in μmol/L?
What is the normal reference range of uric acid in male blood plasma in μmol/L?
- 400-450
- 300-350
- 237.9-356.9 (correct)
- 200-250
What is the result of high blood concentrations of uric acid?
What is the result of high blood concentrations of uric acid?
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What is the enzyme responsible for producing uric acid from xanthine and hypoxanthine?
What is the enzyme responsible for producing uric acid from xanthine and hypoxanthine?
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Study Notes
Uric Acid Structure and Formation
- Uric acid is a heterocyclic compound with the formula C5H4N4O3.
- It is produced from xanthine and hypoxanthine through the action of xanthine oxidase.
- Xanthine and hypoxanthine are derived from purine.
Production Sites
- Uric acid is mainly produced in the liver, kidney, and intestine.
Blood Concentration and Gout
- High blood concentrations of uric acid can lead to gout.
- Normal reference range for uric acid in human blood plasma:
- Male: 237.9～356.9μmol/L (4～7mg/dL)
- Female: 178.4～297.4μmol/L (3～6mg/dL)
- This range is considered normal by the American Association of Medical Physicians.
- Uric acid concentrations above 6mg/dL or below 3mg/dL are considered abnormal.
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