Physiology of Uric Acid
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Questions and Answers

What is the chemical formula of uric acid?

  • C7H7N6O5
  • C5H5N3O2
  • C5H4N4O3 (correct)
  • C6H6N5O4
  • What is the main organ where uric acid is produced?

  • Brain
  • Liver (correct)
  • Heart
  • Lung
  • What is the normal reference range of uric acid in male blood plasma in μmol/L?

  • 400-450
  • 300-350
  • 237.9-356.9 (correct)
  • 200-250
  • What is the result of high blood concentrations of uric acid?

    <p>Gout</p> Signup and view all the answers

    What is the enzyme responsible for producing uric acid from xanthine and hypoxanthine?

    <p>Xanthine oxidase</p> Signup and view all the answers

    Study Notes

    Uric Acid Structure and Formation

    • Uric acid is a heterocyclic compound with the formula C5H4N4O3.
    • It is produced from xanthine and hypoxanthine through the action of xanthine oxidase.
    • Xanthine and hypoxanthine are derived from purine.

    Production Sites

    • Uric acid is mainly produced in the liver, kidney, and intestine.

    Blood Concentration and Gout

    • High blood concentrations of uric acid can lead to gout.
    • Normal reference range for uric acid in human blood plasma:
      • Male: 237.9~356.9μmol/L (4~7mg/dL)
      • Female: 178.4~297.4μmol/L (3~6mg/dL)
    • This range is considered normal by the American Association of Medical Physicians.
    • Uric acid concentrations above 6mg/dL or below 3mg/dL are considered abnormal.

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    Description

    This quiz covers the properties and functions of uric acid in the human body, including its production, reference ranges in blood plasma, and health implications.

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