5 Questions
What is the chemical formula of uric acid?
C5H4N4O3
What is the main organ where uric acid is produced?
Liver
What is the normal reference range of uric acid in male blood plasma in μmol/L?
237.9-356.9
What is the result of high blood concentrations of uric acid?
Gout
What is the enzyme responsible for producing uric acid from xanthine and hypoxanthine?
Xanthine oxidase
Study Notes
Uric Acid Structure and Formation
- Uric acid is a heterocyclic compound with the formula C5H4N4O3.
- It is produced from xanthine and hypoxanthine through the action of xanthine oxidase.
- Xanthine and hypoxanthine are derived from purine.
Production Sites
- Uric acid is mainly produced in the liver, kidney, and intestine.
Blood Concentration and Gout
- High blood concentrations of uric acid can lead to gout.
- Normal reference range for uric acid in human blood plasma:
- Male: 237.9～356.9μmol/L (4～7mg/dL)
- Female: 178.4～297.4μmol/L (3～6mg/dL)
- This range is considered normal by the American Association of Medical Physicians.
- Uric acid concentrations above 6mg/dL or below 3mg/dL are considered abnormal.
This quiz covers the properties and functions of uric acid in the human body, including its production, reference ranges in blood plasma, and health implications.
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