Physiology Chapter on Motor Neurons and Hormones
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Questions and Answers

What is the primary reason for the swelling of ventral horns at the cervical and lumbar enlargements?

  • Increased production of neurotransmitters
  • A larger number of neurons is needed to innervate limb muscles (correct)
  • Development of additional synaptic connections
  • Higher metabolic activity in those regions

What is the collective term for the group of alpha motor neurons that innervate a single muscle?

  • Muscle spindle group
  • Motor neuron pool (correct)
  • Muscle fiber pool
  • Neural circuit

Which input sources to alpha motor neurons are primarily responsible for controlling voluntary movement?

  • Upper motor neurons in the motor cortex and brainstem (correct)
  • Proprioceptors
  • Muscle spindles
  • Local interneurons

Which type of motor neurons is responsible for maintaining the sensitivity of muscle spindles during muscle contraction?

<p>Gamma motor neurons (D)</p> Signup and view all the answers

What is the function of reciprocal inhibition in muscle activity?

<p>Contraction of one muscle set while the antagonist muscle relaxes (A)</p> Signup and view all the answers

What is the primary function of leptin in the body?

<p>Regulates body mass and signals satiety (C)</p> Signup and view all the answers

What occurs when there is a drop in leptin levels?

<p>Decrease in secretion of TSH and ACTH (B)</p> Signup and view all the answers

What is the role of the vagus nerve in the sensation of satiety?

<p>Senses gastric distention and communicates with the NTS (D)</p> Signup and view all the answers

What characterizes the visceromotor response compared to the somatic motor response?

<p>Visceromotor involves involuntary actions, somatic is voluntary (D)</p> Signup and view all the answers

Which hormone is primarily stimulated by TSH in relation to body temperature?

<p>Thyroxine (A)</p> Signup and view all the answers

What psychological role does dopamine play in feeding behavior?

<p>Links the sensory experience of food with emotional reward (A)</p> Signup and view all the answers

What is the physiological basis of gastric distention?

<p>Stretching of the stomach wall during food intake (A)</p> Signup and view all the answers

What is the effect of high levels of ghrelin in the body?

<p>Signals hunger when the stomach is empty (C)</p> Signup and view all the answers

What hormone is primarily involved in mobilizing energy systems during stress responses?

<p>Cortisol (B)</p> Signup and view all the answers

Which neurotransmitter is primarily synthesized and released by the raphae nuclei?

<p>Serotonin (A)</p> Signup and view all the answers

What results from enhanced transmission in the mesocorticolimbic dopamine system due to stimulant drugs?

<p>Formation of addiction (B)</p> Signup and view all the answers

Which of the following systems contains about 500 million neurons and can operate independently?

<p>Enteric nervous system (A)</p> Signup and view all the answers

What type of neurons in the sympathetic system primarily use norepinephrine?

<p>Postganglionic fibers (A)</p> Signup and view all the answers

What is the main function of the locus coeruleus in the brain?

<p>Enhances responsiveness to salient stimuli (B)</p> Signup and view all the answers

During which metabolic state do anabolism and catabolism become relevant?

<p>Post absorptive state (A)</p> Signup and view all the answers

What is primarily stored in adipose tissue?

<p>Triglycerides (C)</p> Signup and view all the answers

How do benzodiazepines and barbiturates work to suppress seizures?

<p>By prolonging inhibitory actions of GABA (D)</p> Signup and view all the answers

What characterizes non-REM sleep?

<p>It is marked by minimal brain activity and no complex dreams (D)</p> Signup and view all the answers

Which of the following statements is true about REM sleep?

<p>It is known for having brain waves similar to those of an awake state (A)</p> Signup and view all the answers

What do circadian rhythms refer to?

<p>Physiological functions that shift in accordance with light/dark cycles (A)</p> Signup and view all the answers

What best describes a free-running circadian rhythm?

<p>A rhythm maintained in the absence of zeitgebers (C)</p> Signup and view all the answers

What is the role of the Raphae nuclei in wakefulness?

<p>They release serotonin to modulate arousal states (C)</p> Signup and view all the answers

Why are chimpanzees limited in their ability to speak human languages?

<p>Their vocal tract is not structured for human phonetics (A)</p> Signup and view all the answers

What was observed about the brain language areas in three-month-old infants?

<p>They exhibited distinct patterns of neural activation related to early language learning (D)</p> Signup and view all the answers

What is a significant argument against the simplicity of language models in processing?

<p>Most aphasia presents with both speech and comprehension deficits, indicating no linear pattern. (C)</p> Signup and view all the answers

During the Wada procedure, what is primarily assessed?

<p>The hemispheric dominance for language and speech. (C)</p> Signup and view all the answers

What is the primary behavior exhibited by subjects with a split brain?

<p>They behave as if they have two separate brains with distinct functions. (A)</p> Signup and view all the answers

Which hemisphere is typically dominant for language processing in most humans?

<p>Left hemisphere is dominant. (B)</p> Signup and view all the answers

What typically occurs in brain activity when a person transitions from performing a task to resting?

<p>Brain activity increases during rest. (B)</p> Signup and view all the answers

What is the consequence of pulvinar lesions in the visual field?

<p>Slower response times to stimuli on the contralateral side. (D)</p> Signup and view all the answers

What is a characteristic of endogenous attention, also known as top-down attention?

<p>Focused goal-directed behavior influenced by internal motives. (D)</p> Signup and view all the answers

What effect does an injection of bicuculline into the pulvinar nucleus have on attention?

<p>It facilitates the shifting of attention to the contralateral side. (B)</p> Signup and view all the answers

Which of the following regions is not a part of the frontoparietal attention network?

<p>Hypothalamus (A)</p> Signup and view all the answers

What helps explain how certain visual features grab one's attention?

<p>Construction of priority map by LIP (D)</p> Signup and view all the answers

How does stimulation of neurons in FEF affect detection threshold?

<p>Improves detection by lowering threshold (A)</p> Signup and view all the answers

What is meant by the neural correlates of consciousness (NCC)?

<p>Minimal neuronal event sufficient for perception of consciousness (D)</p> Signup and view all the answers

What characterizes agoraphobia?

<p>Anxiety about difficulty escaping a situation (B)</p> Signup and view all the answers

Which class of drugs is most commonly used in the treatment of acute anxiety?

<p>Benzodiazepines (A)</p> Signup and view all the answers

What are some of the symptoms of major depression?

<p>Intense feelings of worthlessness and guilt (D)</p> Signup and view all the answers

What is the effect of lithium on the nervous system?

<p>Prevents normal turnover of PIP2 in the neuron (A)</p> Signup and view all the answers

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Flashcards

Lipostatic Hypothesis

The brain monitors the amount of body fat and regulates it to maintain a stable level.

Leptin

A hormone that signals to the brain about energy stores in the body, affecting hunger and satiety.

Satiety Signals

Signals sent to the brain to decrease or stop eating, including the feeling of fullness.

Anorexia

A condition characterized by a loss of appetite and a drastic decrease in food intake.

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Bulimia

A complex eating disorder marked by cycles of overeating (binge) followed by attempts to purge the consumed food.

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Humoral Response

The release and regulation of pituitary hormones, which influence various bodily functions.

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Anterior Hypothalamus

A region of the brain responsible for regulating several vital functions, including homeostasis.

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Thyroid Stimulating Hormone (TSH)

A hormone that stimulates the release of thyroxine, a key hormone in regulating body temperature.

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How do benzodiazepines and barbiturates suppress seizures?

Drugs like benzodiazepines and barbiturates are often prescribed for epilepsy due to their ability to prolong the inhibitory effects of GABA, a neurotransmitter crucial for reducing neuronal excitability.

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What is Non-REM sleep?

Non-REM sleep is characterized by a lack of complex dreams and minimal brain activity. It is a relatively quiet state compared to REM sleep.

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What are Ultradian rhythms?

Ultradian rhythms refer to the cyclical pattern of alternating between slow-wave sleep (approximately 75% of sleep time) and REM sleep (approximately 25% of sleep time).

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What happens to muscle control during REM sleep?

During REM sleep, while the muscles controlling eye movements are very active, the rest of the body is essentially paralyzed. This is vital for preventing physical acting out of dreams.

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Why is REM sleep called paradoxical sleep?

REM sleep is called paradoxical sleep because brain activity patterns during REM resemble wakefulness, even though the body is largely paralyzed. This creates a disconnect between brain activity and physical behavior.

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Explain the Activation-Synthesis Hypothesis of dreaming.

The Activation-Synthesis Hypothesis proposes that dreams are created by the brain's attempt to make sense of random neuronal activity originating in the pons during REM sleep, incorporating memories and associations from the cerebral cortex.

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Which system are sleep and wake neurons part of?

Sleep and wakefulness neurons are part of the diffuse modulatory neurotransmitter system, a network of neurons using different neurotransmitters to modulate widespread areas of the brain.

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Which brain regions and neurotransmitters are involved in sleep-wake transitions?

The Raphe nuclei (serotonin), the locus coeruleus (norepinephrine), and regions in the brainstem and forebrain (acetylcholine) are involved in regulating sleep and wakefulness transitions. Their specific neurotransmitters play crucial roles in maintaining and switching between these states.

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What is a motor neuron pool?

A group of alpha motor neurons that control a single muscle.

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What are muscle spindles?

The specialized sensory receptors located within muscles that provide information about muscle length and changes in muscle length.

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What is reciprocal inhibition?

The contraction of one set of muscles accompanied by the relaxation of its antagonist muscles.

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What is the crossed extensor reflex?

A reflex that helps maintain balance by extending the opposite leg when the other leg is lifted in response to pain.

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What are central pattern generators?

Neural circuits within the spinal cord that generate rhythmic patterns of muscle activity, like walking or breathing.

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What is the Wada procedure?

The Wada procedure is a test used to determine which hemisphere of the brain controls language. It involves temporarily anesthetizing one hemisphere at a time and observing the effects on speech and language abilities. The procedure is used in cases where surgery is being considered for epilepsy, or to understand the localization of language processing in the brain.

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Aphasia in deaf people

Aphasia, the loss of language function, can occur in deaf individuals, indicating that Broca's and Wernicke's areas are involved in broader language processing rather than just speech.

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Non-dominant hemisphere's strengths

The non-dominant (usually right) hemisphere excels at tasks involving spatial processing and visual perception like drawing 3D figures.

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Definition of attention

Attention requires focusing on a specific aspect of sensory input out of the vast amount of information coming in from the environment.

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DMN activity during rest

The default mode network (DMN) is most active during passive, 'restful' states. Our brain remains active even during periods of rest, particularly in tasks requiring internal thinking like daydreaming, recalling memories, and planning.

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Pulvinar and attention

The pulvinar nucleus, a structure in the thalamus, plays a role in attention. Lesions to the pulvinar result in slower responses to stimuli on the opposite side of the body, highlighting its involvement in directing attention.

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Effect of bicuculline on the pulvinar

Injection of bicuculline into the pulvinar nucleus has the opposite effect of a lesion, facilitating attention to the contralateral side.

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Endogenous attention

Endogenous attention, also known as top-down attention, is goal-directed and involves consciously selecting what to focus on based on internal goals or intentions, like actively searching for a specific object or paying attention in class.

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Why is the hypothalamus called the 'master gland'?

The release of hormones from the hypothalamus regulates many other endocrine glands, making it the 'master gland' in the endocrine system.

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What is cortisol and its role during a stress response?

A steroid hormone produced by the adrenal glands during stress, mobilizing energy reserves and suppressing the immune system.

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What is the adrenal medulla's role?

The part of the adrenal gland responsible for releasing adrenaline, a hormone crucial in the fight-or-flight response.

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What is the enteric nervous system?

A network of neurons in the digestive system with its own independent processing abilities, monitoring the chemical conditions of the stomach and intestines.

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What is the noradrenergic modulatory system?

A type of modulatory system using norepinephrine as its neurotransmitter. It originates in the locus coeruleus and speeds up information processing in the cerebral cortex.

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What is the serotonergic modulatory system?

A modulatory system that utilizes serotonin as its neurotransmitter, originating in the raphe nuclei and playing a key role in the sleep-wake cycle.

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What is the dopaminergic modulatory system?

A modulatory system that uses dopamine as its neurotransmitter. It originates in the ventral tegmental area (VTA) and plays significant roles in reward and motivation.

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What is the cholinergic modulatory system?

A modulatory system that utilizes acetylcholine as its neurotransmitter and is present throughout the brain and in the parasympathetic autonomic nervous system.

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What brain regions are part of the frontoparietal attention network?

The prefrontal cortex, FEF (frontal eye field), and Lateral intraparietal cortex (LIP) are all components of this network.

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How are certain features prioritized by the brain?

The Lateral intraparietal cortex (LIP) plays a crucial role in constructing a "priority map" that highlights salient (important) stimuli within our environment.

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How does FEF stimulation affect visual detection?

Electrical stimulation of neurons in the FEF (frontal eye field) leads to a decrease in the detection threshold for visual stimuli, making it easier to notice.

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What are the neural correlates of consciousness (NCC)?

It refers to the minimal set of neuronal events that are necessary for conscious perception.

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What do binocular rivalry experiments help study?

Binocular rivalry offers a powerful tool for studying consciousness, as it allows researchers to investigate brain activity associated with changes in perceived visual dominance.

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What are the common symptoms of general paresis of the insane?

General paresis of the insane, caused by syphilis, involves a progression from mania and cognitive deterioration to paralysis and ultimately death.

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What is the most common psychiatric disorder?

Anxiety disorders, a category of mental illnesses characterized by excessive worry and fear, are the most prevalent psychiatric disorders.

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What are the common symptoms of panic attacks?

A panic attack involves a sudden surge of intense fear or discomfort, often accompanied by physical symptoms like palpitations, sweating, and increased heart rate.

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Study Notes

Chapter Summaries

  • There are several chapters, with each focusing on different aspects of the brain.
  • Different sections of the brain and their roles in memory, emotions, and cognition are covered.
  • The neurobiological mechanisms underlying behaviour, emotion, and memory are outlined
  • Various disorders, pathologies, and clinical cases are used to illustrate concepts.
  • The brain activity and underlying neural mechanisms are explained.

Memory and Learning

  • Memory consolidation is a process that converts short-term memories into long-term memories.
  • The hippocampus plays a crucial role in declarative memory consolidation.
  • Procedural memory is linked to the striatum.
  • Working memory is a type of memory that allows us to hold information briefly in our minds.
  • Retrograde amnesia is the inability to remember events that occurred before a certain traumatic event.
  • Different types of memory and learning are described, along with the neural systems involved.

Language and Cognition

  • Language deficits, such as aphasia, can result from damage to specific brain regions.
  • Broca's area and Wernicke's area are critical for language production and comprehension.
  • The Wernicke-Geschwind model describes the neural pathways involved in language processing.
  • Language processing is described in relation to different brain areas.

Emotions

  • The amygdala is a brain region associated with emotional processing and aggression.
  • The hypothalamus plays a key role in controlling the physiological responses associated with emotions.
  • Different emotional responses and brain areas linked to them are examined.

Sleep

  • Sleep stages and sleep cycles are covered.
  • The neural correlates of sleep are outlined, explaining how specific brain areas are active during different sleep phases.

Brain Structures and Function

  • The brain's structure, and different parts and their functions, are explained.
  • Neural pathways and neurotransmitters are discussed in terms of how they function and interact to have an effect in the brain.
  • Various brain disorders are examined, highlighting specific symptoms; their causal mechanisms are often implied.

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Description

This quiz examines key concepts in physiology, focusing on the functions of alpha motor neurons, the role of hormones like leptin and ghrelin, and the mechanisms of satiety and voluntary movement. Test your understanding of how these elements interact to regulate body functions and behavior.

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