Physiology Chapter: Nervous & Cardiac Systems
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Questions and Answers

What defines isolated systolic hypertension (ISH)?

  • SBP > 140 mm Hg and DBP < 100 mm Hg
  • SBP < 140 mm Hg and DBP < 90 mm Hg
  • SBP > 140 mm Hg and DBP < 90 mm Hg (correct)
  • SBP > 120 mm Hg and DBP < 80 mm Hg
  • Which statement best describes the role of pulse pressure in cardiovascular health?

  • Pulse pressure is only influenced by diastolic blood pressure.
  • Pulse pressure is irrelevant to cardiovascular morbidity.
  • Higher pulse pressures correlate with increased risk of arterial wall stiffness. (correct)
  • Higher pulse pressures are linked to improved cardiovascular function.
  • Which systems are included in the peripheral nervous system (PNS)?

  • Only the sensory nerves connected to the brain
  • Exclusively the autonomic nervous system paralleled with the CNS
  • Nerves that extend from the CNS to limbs and organs (correct)
  • The brain and spinal cord exclusively
  • What is the primary function of the afferent nervous system?

    <p>To relay nerve signals from the PNS to the CNS</p> Signup and view all the answers

    Which portion of the nervous system is primarily responsible for controlling heart rate?

    <p>Autonomic nervous system</p> Signup and view all the answers

    What does the efferent nervous system encompass?

    <p>Both autonomic and somatic motor functions</p> Signup and view all the answers

    Which statement is incorrect regarding the somatic nervous system?

    <p>It is responsible for reflexes independent of conscious control.</p> Signup and view all the answers

    During increased physical activity, what occurs immediately through the autonomic nervous system?

    <p>Increase in heart rate and oxygen delivery to muscles</p> Signup and view all the answers

    What is the first step in the synthesis of catecholamines?

    <p>Importing of tyrosine from extracellular fluid</p> Signup and view all the answers

    In which type of neurons does catecholamine biosynthesis terminate with the production of dopamine?

    <p>Dopaminergic neurons</p> Signup and view all the answers

    Which enzyme directly facilitates the conversion of norepinephrine to epinephrine?

    <p>DA-β-hydroxylase</p> Signup and view all the answers

    What is a significant feature of catecholamine biosynthesis in relation to drug design?

    <p>It has multiple enzymes that can be drug targets.</p> Signup and view all the answers

    Which of the following is a precursor molecule in the synthesis of catecholamines?

    <p>Tyrosine</p> Signup and view all the answers

    What is the main neurotransmitter produced in sympathetic postganglionic neurons?

    <p>Norepinephrine</p> Signup and view all the answers

    What further modification occurs to norepinephrine in the adrenal medulla?

    <p>It is converted to epinephrine.</p> Signup and view all the answers

    Which of the following enzymes is involved in the inactivation of norepinephrine?

    <p>Both B and C</p> Signup and view all the answers

    What primarily contributes to the alteration of blood pressure in short-term neural controls?

    <p>Altering peripheral resistance and cardiac output</p> Signup and view all the answers

    Which mechanism is responsible for detecting an increase in blood pressure via baroreceptors?

    <p>Vasodilation and decreased peripheral resistance</p> Signup and view all the answers

    How do chemoreceptors contribute to blood pressure regulation?

    <p>By monitoring oxygen content and blood pH</p> Signup and view all the answers

    What initiates the vasomotor center to trigger vasoconstriction during blood pressure reduction?

    <p>Signal from baroreceptors</p> Signup and view all the answers

    Which type of control is responsible for long-term blood pressure regulation?

    <p>Renal mechanisms affecting blood volume</p> Signup and view all the answers

    In the case of exercise, how does blood distribution change?

    <p>Less blood is delivered to the gastrointestinal tract</p> Signup and view all the answers

    What type of feedback mechanism is primarily involved in the baroreceptor response?

    <p>Negative feedback to stabilize blood pressure</p> Signup and view all the answers

    What role do higher brain centers play in blood pressure regulation?

    <p>Supply inputs that influence sympathetic nervous activity</p> Signup and view all the answers

    What type of nerve fibers are responsible for transmitting signals in the autonomic nervous system?

    <p>Preganglionic and postganglionic fibers</p> Signup and view all the answers

    What structure acts as clusters of cell bodies where preganglionic and postganglionic fibers connect?

    <p>Ganglia</p> Signup and view all the answers

    How are neurotransmitters released when a nerve signal terminates at the postganglionic nerve fibers?

    <p>Through receptor activation</p> Signup and view all the answers

    Which division of the autonomic nervous system is primarily responsible for increasing heart rate in response to stress?

    <p>Sympathetic division</p> Signup and view all the answers

    What is the main function of the neurotransmitters released at the organ being innervated?

    <p>To transfer nerve signals</p> Signup and view all the answers

    During the autonomic nervous system signal propagation, what manner do nerve signals travel through the fibers?

    <p>Via action potential propagation</p> Signup and view all the answers

    Which of the following is NOT a role of the autonomic nervous system?

    <p>Controlling voluntary muscle movements</p> Signup and view all the answers

    How do neurotransmitters from a postganglionic nerve fiber reach distant sites?

    <p>Via the bloodstream</p> Signup and view all the answers

    Which factor is primarily responsible for the vasoconstriction of smooth muscle in the vasculature?

    <p>Excess stimulation of the RAAS</p> Signup and view all the answers

    What effect does stimulation of the b1-receptors have on the heart?

    <p>Increased heart rate</p> Signup and view all the answers

    The dysfunction of baroreceptors can lead to which of the following outcomes?

    <p>Decreased blood pressure regulation</p> Signup and view all the answers

    Which neurological area is NOT associated with increasing blood pressure when stimulated?

    <p>Vagal nuclei</p> Signup and view all the answers

    How does hyperinsulinemia contribute to increased blood pressure?

    <p>By increasing renal sodium retention</p> Signup and view all the answers

    What is the likely physiological consequence of excess norepinephrine release from presynaptic neurons?

    <p>Increased cardiac output</p> Signup and view all the answers

    Which of the following statements regarding a2-receptors is accurate?

    <p>They block norepinephrine release.</p> Signup and view all the answers

    Genetic alterations of cell membranes can affect which aspect of blood pressure regulation?

    <p>Alter adrenergic receptor responsiveness</p> Signup and view all the answers

    What are the bulbous swellings along the nerve terminal that contain neurotransmitter vesicles called?

    <p>Varicosities</p> Signup and view all the answers

    Which of the following features contributes to the synchronization of smooth muscle contractions?

    <p>Gap junctions</p> Signup and view all the answers

    What is the main structural component of a thin filament in smooth muscle contraction?

    <p>Polymers of actin molecules</p> Signup and view all the answers

    Which site on the myosin head is crucial for ATP splitting during smooth muscle contraction?

    <p>Myosin ATPase site</p> Signup and view all the answers

    What allows smooth muscle to maintain contraction with low energy costs?

    <p>Lengthened contraction cycles</p> Signup and view all the answers

    What primarily influences smooth muscle activity, apart from autonomic neurotransmitters?

    <p>Calcium channel permeability</p> Signup and view all the answers

    How does a smooth muscle contraction occur in relation to filament movement?

    <p>Thin filaments slide inward over thick filaments</p> Signup and view all the answers

    What is a key characteristic of smooth muscle contraction compared to skeletal muscle contraction?

    <p>It can maintain tension for longer durations</p> Signup and view all the answers

    Study Notes

    Learning Objectives

    • Summarize the general function of the parasympathetic and sympathetic nervous systems
    • Differentiate between neurotransmitters and receptors of the parasympathetic and sympathetic systems
    • Compare and contrast cholinergic and adrenergic transmission
    • Describe the biosynthesis and degradation of catecholamines and acetylcholine
    • List the different cholinergic and adrenergic receptors
    • Interpret equations for mean arterial pressure and cardiac output (e.g., define the relationship between stroke volume and cardiac output)
    • Calculate mean arterial pressure
    • Diagram the pathway of blood through the chambers of the heart and peripheral circulatory system
    • Compare and contrast the function of myocardial contractile cells and autorhythmic cells
    • During each phase of the cardiac cycle, compare and contrast ventricular pressure and blood volume in atria and ventricles
    • Define end diastolic volume, end systolic volume, isovolumetric contraction, and isovolumetric relaxation
    • Explain the influence of the parasympathetic and sympathetic nervous system on heart rate and stroke volume
    • Describe factors that regulate stroke volume (preload, contractility, and afterload)
    • Describe the length-tension relationship (Frank-Starling relationship)
    • Compare the structure and function of arteries, arterioles, capillaries, venules, and veins
    • Compare the influence of blood viscosity, vessel length, and vessel diameter on resistance
    • Describe the relationship between cardiac output, blood flow, blood pressure, and resistance
    • Outline the baroreceptor reflex
    • Compare and contrast hormones and their effect on blood pressure (epinephrine, norepinephrine, angiotensin II, ADH, ANP, aldosterone)
    • Illustrate the structure and organization of vascular smooth muscle
    • Outline the steps of smooth muscle contraction (emphasis on Ca2+)
    • Describe the role of smooth muscle cells in influencing vascular tone
    • Illustrate the role of the autonomic nervous system and other mediators on vascular resistance
    • Describe the physiological responses of the autonomic nervous system, the renin-angiotensin-aldosterone system (RAAS), and the kidneys for the regulation of blood pressure
    • Identify pathogenic mechanisms that increase cardiac output and total peripheral resistance
    • Describe the role of peripheral autoregulatory mechanisms, endothelial cells, and electrolytes in the pathophysiology of hypertension

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    Description

    This quiz covers key concepts in physiology related to the parasympathetic and sympathetic nervous systems, including neurotransmitter functions and receptor types. Additionally, it explores the cardiac cycle, mean arterial pressure calculations, and the unique roles of different cardiac cells. Test your understanding of how these systems interact to maintain homeostasis.

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