Physiology Basics Quiz
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Questions and Answers

What percentage of an adult male's body weight is composed of proteins?

  • 18% (correct)
  • 7%
  • 60%
  • 15%

Which factor is NOT mentioned as affecting total body water?

  • Height (correct)
  • Amount of fat
  • Sex
  • Age

What is the primary function of the cell as described?

  • It stores energy for the body.
  • It is the largest structure in living organisms.
  • It is the smallest structural and functional unit. (correct)
  • It regulates blood pressure.

What distinguishes intracellular fluid from extracellular fluid?

<p>ICF and ECF have different compositions. (A)</p> Signup and view all the answers

Which component is the highest in percentage in an adult male's body composition?

<p>Water (B)</p> Signup and view all the answers

As a person ages, what typically happens to their total body water content?

<p>It decreases. (A)</p> Signup and view all the answers

What is the percentage breakdown of extracellular fluid between interstitial fluid and plasma?

<p>1/4 plasma, 3/4 interstitial fluid (D)</p> Signup and view all the answers

What defines the study of Physiology?

<p>The study of normal body functions. (B)</p> Signup and view all the answers

What initiates a vascular spasm during the hemostasis process?

<p>Sympathetic overactivity and pain (B)</p> Signup and view all the answers

Which factor is primarily responsible for platelets adhering to collagen during platelet plug formation?

<p>Von Willebrand factor (C)</p> Signup and view all the answers

What is the final step in the coagulation pathway before the formation of a fibrin mesh?

<p>Conversion of fibrinogen to fibrin (A)</p> Signup and view all the answers

What is the primary function of plasmin in the context of hemostasis?

<p>Break down fibrin (A)</p> Signup and view all the answers

Which of the following substances is NOT involved in stimulating vasoconstriction during hemostasis?

<p>Plasmin (A)</p> Signup and view all the answers

What balance must be maintained to prevent issues during hemostasis?

<p>Between clotting and fibrinolysis (D)</p> Signup and view all the answers

The conversion of prothrombin into thrombin occurs through which process?

<p>Formation of prothrombin activator (D)</p> Signup and view all the answers

What can result from excessive fibrinolysis during the hemostasis process?

<p>Tendency for bleeding (C)</p> Signup and view all the answers

What is the primary cation found in the extracellular fluid (ECF)?

<p>Na+ (C)</p> Signup and view all the answers

What condition arises when water loss exceeds water gain?

<p>Dehydration (C)</p> Signup and view all the answers

Which of the following factors is NOT maintained homeostatically in the internal environment?

<p>Oxygen saturation (A)</p> Signup and view all the answers

Which system is responsible for releasing hormones to regulate cellular functions?

<p>Endocrine system (A)</p> Signup and view all the answers

How is the total body water distributed in an adult male?

<p>66% ICF, 33% ECF (B)</p> Signup and view all the answers

Which of these components makes up the majority of the intracellular fluid (ICF)?

<p>Phosphates (A)</p> Signup and view all the answers

What physiological factor contributes to lower total body water content in females compared to males?

<p>Higher fat percentage (D)</p> Signup and view all the answers

Which body system primarily aids in the defense against foreign invaders?

<p>Immune system (A)</p> Signup and view all the answers

Which of the following is NOT a source of water gain in the body?

<p>Urinating (C)</p> Signup and view all the answers

What is the significance of maintaining a constant pH of 7.4 in the body?

<p>Allows optimal enzyme activity (B)</p> Signup and view all the answers

Which body system facilitates gas exchange, ensuring oxygen uptake and carbon dioxide release?

<p>Respiratory system (C)</p> Signup and view all the answers

What is the main risk of both overhydration and dehydration?

<p>Altered blood composition (B)</p> Signup and view all the answers

What component is vital for the continuous movement of blood in the body?

<p>Heart (D)</p> Signup and view all the answers

Which factor does NOT lead to a decrease in total body water content?

<p>Increased hydration (D)</p> Signup and view all the answers

What is the main cation found in extracellular fluid (ECF)?

<p>Na+ (D)</p> Signup and view all the answers

Which fluid component represents the majority of body fluids?

<p>Interstitial fluid (ISF) (B)</p> Signup and view all the answers

What major ion is predominantly found in intracellular fluid (ICF)?

<p>K+ (C)</p> Signup and view all the answers

Which of the following best describes homeostasis?

<p>Maintenance of internal body conditions (C)</p> Signup and view all the answers

Which system is primarily responsible for transporting water and nutrients around the body?

<p>Circulatory system (D)</p> Signup and view all the answers

What does overhydration refer to?

<p>Excessive water retention in the body (B)</p> Signup and view all the answers

What is a primary cause of dehydration?

<p>Severe vomiting and diarrhea (A)</p> Signup and view all the answers

Which statement about the autonomic nervous system (ANS) is true?

<p>It regulates visceral functions of the body. (D)</p> Signup and view all the answers

What is the primary function of the kidneys in terms of homeostasis?

<p>Filtering blood and removing excess water (D)</p> Signup and view all the answers

Which factor is NOT typically maintained during homeostasis?

<p>External humidity (A)</p> Signup and view all the answers

In terms of body fluid distribution, how is plasma characterized?

<p>It makes up about one-quarter of extracellular fluid. (C)</p> Signup and view all the answers

Which physiological system does NOT contribute directly to homeostasis?

<p>Skeletal system (A)</p> Signup and view all the answers

Which of the following substances is a significant contributor to the composition of intracellular fluid (ICF)?

<p>Phosphates (A)</p> Signup and view all the answers

How much water is generally lost through urine under normal conditions?

<p>1500 ml (D)</p> Signup and view all the answers

Which neurotransmitter is NOT typically released at sympathetic post-ganglionic neurons?

<p>Acetylcholine (A)</p> Signup and view all the answers

What type of adrenergic receptor is activated by norepinephrine in the sympathetic system?

<p>β (beta) receptors (A), α (alpha) receptors (B)</p> Signup and view all the answers

Which statement correctly describes the origins of the sympathetic and parasympathetic systems?

<p>Sympathetic arises from thoracolumbar segments, while parasympathetic arises from cranio-sacral segments. (D)</p> Signup and view all the answers

What is the primary function of globulins in plasma?

<p>Transporting hormones and fat-soluble vitamins (D)</p> Signup and view all the answers

What is the average blood volume in a female individual?

<p>4-5 liters (D)</p> Signup and view all the answers

Which component of blood constitutes approximately 55% of its volume?

<p>Plasma (A)</p> Signup and view all the answers

What type of receptors are present in the autonomic ganglia?

<p>Nicotinic receptors (C)</p> Signup and view all the answers

What is the function of albumin in plasma?

<p>Maintains osmotic pressure (D)</p> Signup and view all the answers

Which of the following cells is NOT categorized as a granulocyte?

<p>Lymphocytes (A)</p> Signup and view all the answers

Which plasma protein is primarily responsible for blood coagulation?

<p>Fibrinogen (B)</p> Signup and view all the answers

What hormonal response is triggered by hypoxia to regulate red blood cell production?

<p>Erythropoietin secretion (D)</p> Signup and view all the answers

Which type of blood cell is primarily responsible for defending against infection?

<p>Leukocytes (B)</p> Signup and view all the answers

Which component of blood is NOT involved in transport functions?

<p>Thrombocytes (A)</p> Signup and view all the answers

Which white blood cells primarily focus on killing parasitic worms?

<p>Eosinophils (D)</p> Signup and view all the answers

What is the average life span of a red blood cell?

<p>120 days (B)</p> Signup and view all the answers

Which nutrient is essential for the synthesis of hemoglobin in red blood cells?

<p>Iron (B)</p> Signup and view all the answers

What type of cell develops into macrophages in tissues?

<p>Monocytes (A)</p> Signup and view all the answers

Which of the following hormones stimulates erythropoietin secretion?

<p>Testosterone (C)</p> Signup and view all the answers

What is the function of basophils in the body?

<p>Release of histamine (D)</p> Signup and view all the answers

Which blood group has no agglutinins in the plasma?

<p>AB (B)</p> Signup and view all the answers

During chemotherapy, which type of cell is primarily affected leading to leukopenia?

<p>Neutrophils (D)</p> Signup and view all the answers

Which of the following statements about lymphocytes is incorrect?

<p>Their development takes 2-3 days. (A)</p> Signup and view all the answers

What is the role of cobalamin (Vitamin B12) in erythropoiesis?

<p>Facilitates RBC maturation (A)</p> Signup and view all the answers

What percentage of white blood cells are lymphocytes?

<p>20%-45% (A)</p> Signup and view all the answers

What is the development time range for neutrophils?

<p>6-9 days (D)</p> Signup and view all the answers

Which factor contributes to the regulation of pH in blood?

<p>Erythrocytes (A)</p> Signup and view all the answers

Which statement about red blood cell structure is correct?

<p>They are disc-shaped for gas exchange. (D)</p> Signup and view all the answers

What is the anatomical origin of the sympathetic nervous system?

<p>Thoracolumbar (C)</p> Signup and view all the answers

Which cranial nerve is responsible for the contraction of the constrictor pupillae muscle?

<p>Oculomotor nerve (III) (B)</p> Signup and view all the answers

Which of the following effects is caused by the sympathetic division on the heart?

<p>Increased excitability (B)</p> Signup and view all the answers

Which division of the autonomic nervous system is associated with inhibition of the bladder wall?

<p>Sympathetic nervous system (D)</p> Signup and view all the answers

What function is performed by the vagus nerve in the respiratory system?

<p>Bronchoconstriction (A)</p> Signup and view all the answers

Which type of autonomic ganglia primarily relays preganglionic sympathetic fibers?

<p>Lateral ganglia (paravertebral) (B)</p> Signup and view all the answers

What effect does the sympathetic nervous system have on the salivary glands?

<p>Stimulates secretion of viscous saliva (A)</p> Signup and view all the answers

Which of the following is a function of the parasympathetic nervous system in the gastrointestinal tract?

<p>Contraction of the gall bladder (C)</p> Signup and view all the answers

Which of the following is true regarding the anatomical origin of the parasympathetic nervous system?

<p>Originates from cranial and sacral regions (C)</p> Signup and view all the answers

Which of the following neurotransmitters is primarily associated with the sympathetic nervous system?

<p>Norepinephrine (A)</p> Signup and view all the answers

Which of the following best describes the function of terminal ganglia?

<p>Relay of preganglionic parasympathetic fibers (B)</p> Signup and view all the answers

Which of the following is NOT a characteristic of splanchnic division functions of the sympathetic nervous system?

<p>Increase gastric motility (B)</p> Signup and view all the answers

What is the primary effect of the parasympathetic nervous system on the heart?

<p>Decreases heart rate (A)</p> Signup and view all the answers

What effect does the sympathetic nervous system have on the skin?

<p>Stimulates hair follicle contraction (B)</p> Signup and view all the answers

Flashcards

What is Physiology?

The study of the normal functions of a living organism.

What is a cell?

The basic unit of structure and function in living organisms. It is the smallest structure capable of independent functioning.

What is Intracellular Fluid (ICF)?

The water inside the cells, making up about 2/3 of our total body water.

What is Extracellular Fluid (ECF)?

The water outside the cells, making up about 1/3 of our total body water.

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What is Interstitial Fluid (ISF)?

The part of the extracellular fluid that is found between cells, making up 3/4 of the ECF.

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What is Plasma?

The liquid component of blood, making up 1/4 of the ECF.

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What is Homeostasis?

The maintenance of a stable internal environment despite changing external conditions.

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What is the internal environment of the body?

The state of being balanced and constant, allowing your body to function properly.

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Intracellular Fluid (ICF)

The fluid inside cells, essential for cellular function.

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Extracellular Fluid (ECF)

The fluid outside cells, acting as the internal environment of the body.

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Homeostasis

The process of maintaining stable internal conditions in the body, like temperature or pH.

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External Environment

It is the surrounding environment that an organism lives in.

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Internal Environment

The fluid that surrounds cells in the body, also known as the internal environment.

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Autonomic Nervous System (ANS)

Regulates involuntary functions like heart rate, digestion, and breathing.

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Somatic Nervous System

The part of the nervous system that controls voluntary muscle movement.

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Neuron

A nerve cell, the fundamental unit of the nervous system.

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Sympathetic Nervous System

A branch of the ANS that prepares the body for 'fight or flight' responses.

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Parasympathetic Nervous System

A branch of the ANS that promotes 'rest and digest' functions.

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Physiology

The study of normal functions of a living organism. It focuses on how body parts work.

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Cell

The basic unit of life. The smallest structure capable of independent function, forming the building blocks of tissues.

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Sodium (Na+)

The main ECF cation, found in large quantities in the extracellular fluid.

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Potassium (K+)

The main ICF cation, found in large quantities in the intracellular fluid.

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Increased chances of survival

The ability to survive in various conditions due to the maintenance of a stable internal environment.

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Freedom to live in a variety of conditions

The ability to live in a variety of environments thanks to a stable internal environment.

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Permit proper functioning of the brain

Proper functioning of the brain relies on a stable internal environment.

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Circulatory System

The system that transports blood throughout the body, delivering oxygen and nutrients while removing waste.

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Musculoskeletal System

The system that helps the body move to obtain food and protect itself from danger.

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Endocrine System

The system that regulates cellular functions using hormones.

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Kidney and Urinary System

The system that removes waste and excess water from the blood, maintaining fluid balance.

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Vascular Spasm

The first step in hemostasis, where the damaged blood vessel constricts to reduce blood flow.

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Platelet Plug Formation

The second step of hemostasis, where platelets adhere to the damaged blood vessel wall and form a temporary plug.

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Blood Clotting (Coagulation)

The final stage of hemostasis, where a blood clot forms to permanently seal the damaged vessel.

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Prothrombin Activator

A substance released during coagulation that is crucial for converting prothrombin into thrombin, a key enzyme in blood clotting.

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Thrombin

A key protein involved in blood clotting, it converts fibrinogen into fibrin.

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Fibrin

A mesh-like protein that forms the structure of a blood clot, made from fibrinogen.

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Fibrinolysis

The process that dissolves blood clots, preventing them from blocking blood vessels.

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What are autonomic ganglia?

A collection of nerve cells located outside the central nervous system (CNS), containing the nerve cells of the postganglionic neurons.

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Where does the sympathetic nervous system originate?

The sympathetic nervous system originates from the thoracolumbar region of the spinal cord (T1-L3).

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Where does the parasympathetic nervous system originate?

The parasympathetic nervous system originates from the craniosacral region, meaning from the brain and the sacral region of the spinal cord (cranial nerves III, VII, IX, X and S2-S4).

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What is the sympathetic chain?

The sympathetic chain is a series of interconnected ganglia located on both sides of the vertebral column. It serves as a relay point for preganglionic sympathetic fibers.

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What are collateral ganglia?

Collateral ganglia are located in the abdomen, near the major branches of the aorta. They relay both preganglionic sympathetic and parasympathetic fibers, primarily sympathetic.

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What are terminal ganglia?

Terminal ganglia are located close to or on the wall of effector organs. They relay only preganglionic parasympathetic fibers.

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What are the functions of autonomic ganglia?

Autonomic ganglia act as relay stations for preganglionic nerves and are the origin of postganglionic nerves.

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What is the main function of the sympathetic nervous system?

The sympathetic nervous system is responsible for "fight-or-flight" responses, preparing the body for action and stress.

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What is the main function of the parasympathetic nervous system?

The parasympathetic nervous system is responsible for "rest-and-digest" functions, promoting relaxation and slowing down bodily processes.

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What neurotransmitter does the sympathetic nervous system use?

The sympathetic nervous system uses norepinephrine (noradrenaline) as its main neurotransmitter.

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What neurotransmitter does the parasympathetic nervous system use?

The parasympathetic nervous system uses acetylcholine as its main neurotransmitter.

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What are adrenergic receptors?

Adrenergic receptors are the target receptors for norepinephrine (noradrenaline) released by the sympathetic nervous system.

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What are muscarinic receptors?

Muscarinic receptors are the target receptors for acetylcholine released by the parasympathetic nervous system.

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What are some specific effects of the sympathetic nervous system?

The sympathetic nervous system increases heart rate, dilates pupils, and constricts blood vessels to redirect blood flow to muscles and the brain.

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What are some specific effects of the parasympathetic nervous system?

The parasympathetic nervous system decreases heart rate, constricts pupils, and stimulates digestion and other "rest-and-digest" functions.

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Preganglionic neuron

The nerve cell in the autonomic nervous system that transmits signals from the central nervous system to the autonomic ganglia.

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Postganglionic neuron

The nerve cell in the autonomic nervous system that transmits signals from the autonomic ganglia to the target organs.

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Autonomic ganglia

Clusters of nerve cells in the autonomic nervous system where preganglionic neurons synapse with postganglionic neurons.

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Cholinergic system

The division of the autonomic nervous system that uses acetylcholine as its primary neurotransmitter.

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Noradrenergic system

The division of the autonomic nervous system that uses norepinephrine as its primary neurotransmitter.

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Cholinergic receptor

A type of receptor found in the autonomic nervous system that is activated by acetylcholine.

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Nicotinic receptor

A type of cholinergic receptor found in the autonomic ganglia.

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Muscarinic receptor

A type of cholinergic receptor found in the target organs of the parasympathetic nervous system.

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Adrenergic receptor

A type of receptor found in the autonomic nervous system that is activated by norepinephrine.

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Alpha receptor (α)

A type of adrenergic receptor that binds to norepinephrine.

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Beta receptor (β)

A type of adrenergic receptor that binds to norepinephrine.

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Plasma

The liquid component of blood that contains water, proteins, and other dissolved substances.

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Hematocrit

The fraction of blood volume occupied by red blood cells.

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Erythropoiesis

The process of red blood cell formation.

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Leucopoiesis

The process of white blood cell formation.

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What are agranulocytes?

White blood cells lacking obvious granules in their cytoplasm. These include lymphocytes and monocytes, which play crucial roles in the immune system.

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Describe neutrophils.

A type of white blood cell responsible for phagocytizing bacteria. They are the most abundant type of white blood cell, making up 40%-70% of the total.

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What are granulocytes?

White blood cells that contain granules filled with enzymes and other substances. They play important roles in allergic reactions and parasitic infections.

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Explain eosinophils.

A type of granulocyte that plays a role in killing parasitic worms and destroying antigen-antibody complexes. They make up 1%-4% of white blood cells.

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What are basophils?

A type of granulocyte involved in allergic reactions. Their granules contain histamine and heparin, which are released during inflammation.

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Describe lymphocytes.

A type of agranulocyte that plays a key role in the adaptive immune system. They are involved in the production of antibodies (B cells) and direct cell attack (T cells).

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Explain monocytes.

A type of agranulocyte that develops into macrophages in tissues. They are phagocytic and play a role in clearing debris and pathogens.

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What is leukopenia?

A condition characterized by a decrease in the number of white blood cells. It can be caused by various factors, including chemotherapy.

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What are erythrocytes?

Red blood cells are responsible for transporting oxygen throughout the body. They are biconcave in shape, which increases their surface area for gas exchange.

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What is hemoglobin?

The protein found in red blood cells that binds oxygen and carbon dioxide for transport.

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What is erythropoiesis?

The process of red blood cell production, primarily occurring in the red bone marrow.

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What is erythropoietin?

A hormone produced mainly by the kidneys (85%) and liver (15%) that stimulates the production of red blood cells in response to low oxygen levels.

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What is anemia?

A decrease in the number of red blood cells, hemoglobin concentration, or both. This leads to a reduction in oxygen delivery to the tissues.

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What are blood group antigens?

Chemical groups found on the surface of red blood cells that determine a person's blood type. These groups are antigenic, meaning they can trigger an immune response.

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What is the ABO blood group system?

A system for classifying blood types based on the presence or absence of A and B antigens on red blood cells. There are four main blood types: A, B, AB, and O.

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What is the Rh blood group system?

A system for classifying blood types based on the presence or absence of the RhD antigen on red blood cells. Individuals who have the RhD antigen are Rh-positive, while those who lack it are Rh-negative.

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Study Notes

Blood Composition and Physiology

  • Blood is a liquid connective tissue, forming approximately 8% of a 70 kg male's body weight.
  • Average blood volume is 5-6 liters in males and 4-5 liters in females.
  • Blood is composed of:
    • Plasma (55%)
    • Blood cells (45%)
      • Erythrocytes (RBCs)
      • Leukocytes (WBCs)
      • Thrombocytes (platelets)
  • Hematocrit (PCV) is the percentage of RBCs in total blood volume.

Blood Functions

  • Transport: Gases (oxygen and carbon dioxide), nutrients, hormones, and waste products.
  • Regulation: Acid-base balance, blood pressure.
  • Defense: Against infection (WBCs and immune system).
  • Hemostasis: Stoppage of bleeding (platelets and clotting factors).

Plasma Composition

  • Plasma is 90% water, 9% organic constituents (proteins, etc.), inorganic constituents, and blood gases.
  • Plasma that has had clotting factors removed is called serum.
  • Plasma proteins include:
    • Albumin: Maintains osmotic pressure, transports molecules.
    • Globulins: Transport hormones and fat-soluble vitamins; gamma globulins are antibodies.
    • Fibrinogen: Forms fibrin for blood clots.
    • Prothrombin: Plays a role in blood clotting.

Blood Cells: Leukocytes (White Blood Cells)

  • Major categories:
    • Granulocytes: Neutrophils (most common, engulf bacteria), eosinophils (combat parasites, destroy antigen-antibody complexes), basophils (release histamine and heparin).
    • Agranulocytes: Lymphocytes (T cells and B cells, immune responses), monocytes (phagocytic, develop into macrophages in tissues).

Blood Cells: Erythrocytes (Red Blood Cells)

  • Average count: 5 million/mm³ in males, 4.2-5.2 million/mm³ in females.
  • Biconcave disc shape for gas exchange, flexible for capillary passage.
  • Primary component: Hemoglobin (Hb) for oxygen and carbon dioxide transport.
  • No nucleus or mitochondria.
  • Life span: 120 days.
  • Erythropoiesis: RBC production.
  • Sites of RBC formation:
    • Fetus: Liver and spleen
    • Children: Red bone marrow of axial and appendicular skeletons.
    • Adults: Primarily red bone marrow of axial skeleton.

Erythropoiesis Regulation

  • Hypoxia: Low oxygen stimulates erythropoietin (EPO) production.

  • EPO source: Primarily kidney (85%), some liver (15%)

  • Nutrients for Erythropoiesis:

    • Vitamin B12 (liver)
    • Folic Acid (leaves, fish)
    • Vitamin B6 (eggs, whole grains)
    • Amino acids (protein resources)
    • Vitamin C (absorption aid)
    • Iron: Essential for Hb synthesis.
  • Hormones Affecting Erythropoiesis:

    • Testosterone stimulates EPO.
    • Thyroid hormones increase cell metabolism.
    • Cortisol increases RBC formation.

Blood Groups

  • ABO system: Based on antigens (A, B) on RBCs.
  • Rh system: Presence/absence of antigen D determines Rh+ or Rh-.
    • Rh+ve is common (85%).

Hemostasis (Blood Clotting)

  • A series of steps that stop bleeding.
  • Stages:
    • Vascular spasm: Initiated by nerve impulses and chemical factors.
    • Platelet plug formation: Platelets adhere to collagen and degranulate, releasing factors to enhance clotting and cause vasoconstriction.
    • Coagulation: Intrinsic and extrinsic pathways result in thrombin converting fibrinogen to fibrin for clot formation.
  • Fibrinolysis: Breakdown of fibrin by plasmin, preventing clots from staying too long.

Anticoagulants

  • Prevent blood clotting.

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Test your knowledge of fundamental physiological concepts, including body composition, fluid distribution, and the functions of cells. This quiz will challenge your understanding of how various factors affect the human body and its workings. Perfect for students of biology and health sciences.

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