Body Fluid Distribution and Composition
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Questions and Answers

What is the primary function of sodium in the body?

  • Neutralizing charge with potassium ions
  • Regulating blood pressure
  • Maintaining skin integrity
  • Regulating water balance (correct)
  • What is the normal range of sodium levels in the blood?

  • 120-130 mEq/L
  • 135-145 mEq/L (correct)
  • 145-155 mEq/L
  • 155-165 mEq/L
  • Which hormone regulates sodium reabsorption in the renal tubules?

  • Thyroxine
  • Adrenaline
  • Insulin
  • Aldosterone (correct)
  • What percentage of total body weight is made up of Intracellular Fluids (ICF)?

    <p>42%</p> Signup and view all the answers

    What is the term for an abnormally low concentration of sodium in the blood?

    <p>Hyponatremia</p> Signup and view all the answers

    What is the term for the fluid outside of cells, including interstitial, intravascular, and transcellular fluid?

    <p>Extracellular Fluid (ECF)</p> Signup and view all the answers

    Why should patients with fluid volume excess avoid high-sodium foods?

    <p>To reduce fluid retention and swelling</p> Signup and view all the answers

    How often should nurses assess circulation to extremities in patients with fluid volume excess?

    <p>Every 8 hours</p> Signup and view all the answers

    What is the charge of ions such as Na+, K+, and Ca++?

    <p>Positively charged</p> Signup and view all the answers

    What is the term for the movement of water into or out of a cell based on the concentration of solutes?

    <p>Osmosis</p> Signup and view all the answers

    What is the normal concentration of potassium (K+) in the intravascular fluid?

    <p>5 mEq/L</p> Signup and view all the answers

    What is the main function of the kidney in maintaining fluid and electrolyte homeostasis?

    <p>Ion transport and water movement</p> Signup and view all the answers

    What would happen if a red blood cell was placed in a hypotonic solution?

    <p>The cell would swell</p> Signup and view all the answers

    What percentage of total body fluid is made up of Extracellular Fluid (ECF) in a newborn infant?

    <p>More than 50%</p> Signup and view all the answers

    What is the primary mechanism of osmosis?

    <p>Diffusion of water across a selectively permeable membrane</p> Signup and view all the answers

    Which hormone regulates fluid intake?

    <p>Thirst</p> Signup and view all the answers

    What is the primary characteristic of diabetes insipidus?

    <p>Deficiency of ADH leading to polyuria and polydipsia</p> Signup and view all the answers

    What is the treatment for severe hyponatremia with CNS symptoms?

    <p>Saline (3% or 5% NaCl) in addition to fluid restriction and furosemide</p> Signup and view all the answers

    What is the primary cause of hypovolemia?

    <p>Loss of ECF volume exceeding the intake of fluid</p> Signup and view all the answers

    What is the laboratory finding in hypovolemia?

    <p>Increased hgb and hct, increased serum and urine osmolality and specific gravity</p> Signup and view all the answers

    What is the primary characteristic of SIADH?

    <p>Inappropriate secretion of ADH with water retention</p> Signup and view all the answers

    What is the primary mechanism of filtration?

    <p>Movement across a membrane, under pressure, from higher to lower pressure</p> Signup and view all the answers

    What is the primary function of atrial natriuretic peptide?

    <p>Inhibition of aldosterone secretion</p> Signup and view all the answers

    What is the primary cause of hypervolemia?

    <p>Overzealous administration of Na+ fluids</p> Signup and view all the answers

    What is the primary indicator of fluid volume status in an adult?

    <p>Daily weights</p> Signup and view all the answers

    What is the consequence of hypervolemia?

    <p>Edema and hypertension</p> Signup and view all the answers

    What is the primary cause of fluid volume excess?

    <p>Increased total body sodium content</p> Signup and view all the answers

    What is the result of isotonic retention of body substances in hypervolemia?

    <p>Essentially normal serum sodium concentration</p> Signup and view all the answers

    What is a common complication of severe volume overload?

    <p>Pulmonary edema</p> Signup and view all the answers

    What is the goal of collaborative care management for fluid volume excess?

    <p>To restore normal fluid balance and provide symptomatic care</p> Signup and view all the answers

    What is the result of trapping water in the interstitial spaces?

    <p>Unavailability of water for metabolic processes</p> Signup and view all the answers

    What is the term for the accumulation of fluid within the interstitial spaces?

    <p>Edema</p> Signup and view all the answers

    What is a common cause of fluid volume deficit?

    <p>Vomiting and diarrhea</p> Signup and view all the answers

    What is a nursing consideration for edema of specific organs?

    <p>Edema can be life-threatening</p> Signup and view all the answers

    What is a significant complication of severe volume overload?

    <p>Pulmonary edema</p> Signup and view all the answers

    What is the primary indicator of fluid volume status in an adult?

    <p>Daily weights</p> Signup and view all the answers

    What is the term for the accumulation of fluid within the interstitial spaces?

    <p>Edema</p> Signup and view all the answers

    What is the consequence of hypervolemia?

    <p>Pulmonary edema</p> Signup and view all the answers

    What is the goal of collaborative care management for fluid volume excess?

    <p>Restore normal fluid balance</p> Signup and view all the answers

    What is the result of isotonic retention of body substances in hypervolemia?

    <p>No change in serum sodium concentration</p> Signup and view all the answers

    What is a common cause of fluid volume deficit?

    <p>Vomiting and diarrhea</p> Signup and view all the answers

    What is a nursing consideration for edema of specific organs?

    <p>Edema of specific organs can be life-threatening</p> Signup and view all the answers

    What is a common complication of fluid volume excess?

    <p>Pulmonary edema</p> Signup and view all the answers

    What is the result of trapping water in the interstitial spaces?

    <p>Edema</p> Signup and view all the answers

    What is the primary mechanism of active transport?

    <p>Movement of ions against osmotic pressure to an area of higher pressure</p> Signup and view all the answers

    Which hormone regulates fluid output in the kidneys?

    <p>Antidiuretic hormone</p> Signup and view all the answers

    What is the primary characteristic of Diabetes Insipidus?

    <p>ADH deficiency leading to polyuria and polydipsia</p> Signup and view all the answers

    What is the primary cause of hypovolemia?

    <p>Inadequate fluid intake and anorexia</p> Signup and view all the answers

    What is the laboratory finding in SIADH?

    <p>Low serum sodium and osmolarity</p> Signup and view all the answers

    What is the treatment for mild hyponatremia?

    <p>Fluid restriction and increased salt intake</p> Signup and view all the answers

    What is the primary mechanism of osmosis?

    <p>Diffusion of water across a selectively permeable membrane</p> Signup and view all the answers

    What is the primary characteristic of hypovolemia?

    <p>Loss of water and electrolytes in the same proportion as they exist in normal body fluids</p> Signup and view all the answers

    What is the primary function of atrial natriuretic peptide?

    <p>Inhibition of renin-angiotensin-aldosterone mechanism</p> Signup and view all the answers

    What is the primary mechanism of filtration?

    <p>Movement across a membrane under pressure</p> Signup and view all the answers

    What is the primary goal of dietary modifications for patients with fluid volume excess?

    <p>To control fluid volume and reduce sodium intake</p> Signup and view all the answers

    Why are patients with fluid volume excess advised to elevate their extremities?

    <p>To reduce dependent edema, except in cases of significant heart failure or pulmonary edema</p> Signup and view all the answers

    What is the role of sodium in regulating water balance in the body?

    <p>To play a crucial role in regulating water balance</p> Signup and view all the answers

    Which of the following hormones does NOT regulate sodium reabsorption in the renal tubules?

    <p>Insulin</p> Signup and view all the answers

    What is thepurpose of monitoring jugular neck veins and hand veins in patients with fluid volume excess?

    <p>To monitor fluid volume status</p> Signup and view all the answers

    What is the consequence of fluid volume excess on the body?

    <p>Edema and potentially heart failure</p> Signup and view all the answers

    What percentage of total body weight is made up of Extracellular Fluid (ECF)?

    <p>17%</p> Signup and view all the answers

    What happens when a red blood cell is placed in a hypotonic solution?

    <p>The cell will swell and possibly burst</p> Signup and view all the answers

    What is the primary mechanism of maintaining fluid and electrolyte homeostasis in the body?

    <p>Water movement, ion transport, and kidney function</p> Signup and view all the answers

    What is the normal concentration of sodium (Na+) in the intravascular fluid?

    <p>142 mEq/L</p> Signup and view all the answers

    What happens when a red blood cell is placed in a hypertonic solution?

    <p>The cell will shrink</p> Signup and view all the answers

    What percentage of total body fluid is made up of Extracellular Fluid (ECF) in a newborn infant?

    <p>50%</p> Signup and view all the answers

    What is the primary function of electrolytes in the body?

    <p>To facilitate nerve and muscle function</p> Signup and view all the answers

    What is the term for the movement of water into or out of a cell based on the concentration of solutes?

    <p>Osmosis</p> Signup and view all the answers

    Study Notes

    Fluid and Electrolytes

    • Distribution of body fluids:
      • Intracellular fluids (ICF): 42% of total body weight, 28 liters in males, 20 liters in females
      • Extracellular fluids (ECF): 17% of total body weight, consists of interstitial, intravascular, and transcellular fluids

    Electrolytes

    • Definition: charged particles (ions) dissolved in body fluids
    • Types of electrolytes:
      • Cations (positively charged): Na+, K+, Ca++, H+
      • Anions (negatively charged): Cl-, HCO3-, PO43-
    • Electrolyte concentration differs in ICF and ECF

    Normal Electrolyte Content and Body Fluids

    • Sodium (Na+): 142-146 mEq/L in ECF, 15 mEq/L in ICF
    • Potassium (K+): 5 mEq/L in ECF, 150 mEq/L in ICF
    • Calcium (Ca++): 5 mEq/L in ECF, 2 mEq/L in ICF
    • Chloride (Cl-): 102-114 mEq/L in ECF, 1 mEq/L in ICF
    • Bicarbonate (HCO3-): 27 mEq/L in ECF, 10 mEq/L in ICF

    Homeostasis

    • Maintained by:
      • Water movement
      • Ion transport
      • Kidney function
    • Regulation of body fluids:
      • Thirst regulates fluid intake
      • Fluid output: kidneys, skin, lungs, and GI tract

    Fluid Movement

    • Types of fluid movement:
      • Diffusion: movement of dissolved particles through a semipermeable membrane
      • Osmosis: diffusion of water across a selectively permeable membrane
      • Filtration: movement across a membrane under pressure
      • Active transport: movement of ions against osmotic pressure

    Diabetes Insipidus

    • Causes:
      • Hypothalamic tumors, leukemia, lymphoma, sarcoidosis, head trauma, general anesthetics
      • Oat-cell carcinoma of the lung, leukemia, head injury, brain tumor, pneumonia, acute respiratory failure, tuberculosis
    • Pathophysiology:
      • ADH deficiency leading to polyuria and polydipsia
      • Inappropriate secretion of ADH with water retention
    • Laboratory findings:
      • Normal serum sodium and osmolarity if thirst mechanisms intact
      • Low serum sodium and osmolarity if thirst mechanisms impaired
    • Signs and symptoms:
      • Polyuria, nocturia, continuous thirst, polydipsia, craving ice water
      • Weight gain, fingerprinting edema, no peripheral edema

    Hypovolemia

    • Definition: fluid volume deficit occurs when loss of ECF volume exceeds intake of fluid
    • Causes:
      • Vomiting, diarrhea, fistulas, fever, excessive sweating, burns, blood loss, GI suction, 3rd space fluid shifts, decreased intake
    • Signs and symptoms:
      • Acute weight loss, decreased skin turgor, oliguria, concentrated urine, weak rapid pulse, > cap refill, low CVP, hypotension, flat neck veins, dizzy, weak, increased thirst, confusion, tachycardia, muscle cramps, sunken eyes
    • Laboratory findings:
      • Increased hgb and hct, increased serum and urine osmolality and specific gravity, decreased urine sodium, increased BUN and creatinine, increased urine specific gravity and osmolality

    Hypervolemia

    • Definition: fluid volume excess occurs when abnormal retention of water and sodium in ECF
    • Causes:
      • Compromised regulatory mechanisms: renal failure, heart failure, cirrhosis, overzealous admin of Na+ fluids, fluid shifts, prolonged corticosteroid therapy, severe stress, hyperaldosteronism
    • Signs and symptoms:
      • Acute weight gain, peripheral edema and ascites, distended jugular veins, crackles, elevated CVP, SOB, hypertension, bounding pulse, cough, tachypnea
    • Laboratory findings:
      • Decreased hgb and hct, decreased serum and urine osmolality, decreased urine sodium and specific gravity

    Fluid Volume Deficit; Nursing Care

    • Assess vital signs regularly
    • Postural (orthostatic) hypotension: ↓ in sys BP > 15 mmHg or ↑ HR > 15 beats/min
    • Daily weights: single best indicator of fluid volume status in adults
    • Apply safety measures: orthostatic hypotension, dizziness, and falls
    • Accurate record of intake and output: record drainage from body orifices and wound(s)
    • Administer free water (flush) to patients receiving enteral feedings
    • Urge caution in drinking coffee, tea, and colas with caffeine, which has a diuretic effect

    Fluid and Electrolytes

    • Distribution of body fluids:
      • Intracellular fluids (ICF): 42% of total body weight, 28 liters in males, 20 liters in females
      • Extracellular fluids (ECF): 17% of total body weight, consists of interstitial, intravascular, and transcellular fluids

    Electrolytes

    • Definition: charged particles (ions) dissolved in body fluids
    • Types of electrolytes:
      • Cations (positively charged): Na+, K+, Ca++, H+
      • Anions (negatively charged): Cl-, HCO3-, PO43-
    • Electrolyte concentration differs in ICF and ECF

    Normal Electrolyte Content and Body Fluids

    • Sodium (Na+): 142-146 mEq/L in ECF, 15 mEq/L in ICF
    • Potassium (K+): 5 mEq/L in ECF, 150 mEq/L in ICF
    • Calcium (Ca++): 5 mEq/L in ECF, 2 mEq/L in ICF
    • Chloride (Cl-): 102-114 mEq/L in ECF, 1 mEq/L in ICF
    • Bicarbonate (HCO3-): 27 mEq/L in ECF, 10 mEq/L in ICF

    Homeostasis

    • Maintained by:
      • Water movement
      • Ion transport
      • Kidney function
    • Regulation of body fluids:
      • Thirst regulates fluid intake
      • Fluid output: kidneys, skin, lungs, and GI tract

    Fluid Movement

    • Types of fluid movement:
      • Diffusion: movement of dissolved particles through a semipermeable membrane
      • Osmosis: diffusion of water across a selectively permeable membrane
      • Filtration: movement across a membrane under pressure
      • Active transport: movement of ions against osmotic pressure

    Diabetes Insipidus

    • Causes:
      • Hypothalamic tumors, leukemia, lymphoma, sarcoidosis, head trauma, general anesthetics
      • Oat-cell carcinoma of the lung, leukemia, head injury, brain tumor, pneumonia, acute respiratory failure, tuberculosis
    • Pathophysiology:
      • ADH deficiency leading to polyuria and polydipsia
      • Inappropriate secretion of ADH with water retention
    • Laboratory findings:
      • Normal serum sodium and osmolarity if thirst mechanisms intact
      • Low serum sodium and osmolarity if thirst mechanisms impaired
    • Signs and symptoms:
      • Polyuria, nocturia, continuous thirst, polydipsia, craving ice water
      • Weight gain, fingerprinting edema, no peripheral edema

    Hypovolemia

    • Definition: fluid volume deficit occurs when loss of ECF volume exceeds intake of fluid
    • Causes:
      • Vomiting, diarrhea, fistulas, fever, excessive sweating, burns, blood loss, GI suction, 3rd space fluid shifts, decreased intake
    • Signs and symptoms:
      • Acute weight loss, decreased skin turgor, oliguria, concentrated urine, weak rapid pulse, > cap refill, low CVP, hypotension, flat neck veins, dizzy, weak, increased thirst, confusion, tachycardia, muscle cramps, sunken eyes
    • Laboratory findings:
      • Increased hgb and hct, increased serum and urine osmolality and specific gravity, decreased urine sodium, increased BUN and creatinine, increased urine specific gravity and osmolality

    Hypervolemia

    • Definition: fluid volume excess occurs when abnormal retention of water and sodium in ECF
    • Causes:
      • Compromised regulatory mechanisms: renal failure, heart failure, cirrhosis, overzealous admin of Na+ fluids, fluid shifts, prolonged corticosteroid therapy, severe stress, hyperaldosteronism
    • Signs and symptoms:
      • Acute weight gain, peripheral edema and ascites, distended jugular veins, crackles, elevated CVP, SOB, hypertension, bounding pulse, cough, tachypnea
    • Laboratory findings:
      • Decreased hgb and hct, decreased serum and urine osmolality, decreased urine sodium and specific gravity

    Fluid Volume Deficit; Nursing Care

    • Assess vital signs regularly
    • Postural (orthostatic) hypotension: ↓ in sys BP > 15 mmHg or ↑ HR > 15 beats/min
    • Daily weights: single best indicator of fluid volume status in adults
    • Apply safety measures: orthostatic hypotension, dizziness, and falls
    • Accurate record of intake and output: record drainage from body orifices and wound(s)
    • Administer free water (flush) to patients receiving enteral feedings
    • Urge caution in drinking coffee, tea, and colas with caffeine, which has a diuretic effect

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    Description

    Learn about the distribution of body fluids, including intracellular and extracellular fluids, and how they change with age. Understand the composition of fluids in the human body.

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