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Questions and Answers
What is the physical property of ergotamine in relation to its solubility?
What is the physical property of ergotamine in relation to its solubility?
- Slightly soluble in water, insoluble in alcohol, freely soluble in CHCl3 and ether
- Freely soluble in water, insoluble in alcohol, slightly soluble in CHCl3 and ether
- Insoluble in water, slightly soluble in alcohol, freely soluble in CHCl3 and ether (correct)
- Freely soluble in water, slightly soluble in alcohol, insoluble in CHCl3 and ether
What specific reaction results in a blue color for ergot alkaloids?
What specific reaction results in a blue color for ergot alkaloids?
- Conc H2SO4
- Van Urk test
- Conc H2SO4 + glacial acetic acid containing a trace of FeCl3 (correct)
- Aqueous solution of alkaloidal salts
What is the source of physostigmine?
What is the source of physostigmine?
- Ergotamine biosynthesis from tryptophan+SAM (pyrrolidine indole =indoline)
- Fermentation using Streptomyces griseofuscus
- Calabar bean alkaloids Me HO NMe NMe Pyrrolydine indole
- Seeds of Physostigma venenosum (Fabaceae) containing 0.15% alkaloids (correct)
What pharmacological action does physostigmine exhibit?
What pharmacological action does physostigmine exhibit?
For what medical condition is physostigmine used?
For what medical condition is physostigmine used?