Physical Properties and Reactions of Ergotamine
5 Questions
2 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What is the physical property of ergotamine in relation to its solubility?

  • Slightly soluble in water, insoluble in alcohol, freely soluble in CHCl3 and ether
  • Freely soluble in water, insoluble in alcohol, slightly soluble in CHCl3 and ether
  • Insoluble in water, slightly soluble in alcohol, freely soluble in CHCl3 and ether (correct)
  • Freely soluble in water, slightly soluble in alcohol, insoluble in CHCl3 and ether

    • What specific reaction results in a blue color for ergot alkaloids?

  • Conc H2SO4
  • Van Urk test
  • Conc H2SO4 + glacial acetic acid containing a trace of FeCl3 (correct)
  • Aqueous solution of alkaloidal salts

    • What is the source of physostigmine?

  • Ergotamine biosynthesis from tryptophan+SAM (pyrrolidine indole =indoline)
  • Fermentation using Streptomyces griseofuscus
  • Calabar bean alkaloids Me HO NMe NMe Pyrrolydine indole
  • Seeds of Physostigma venenosum (Fabaceae) containing 0.15% alkaloids (correct)

    • What pharmacological action does physostigmine exhibit?

    <p>Reversible choline esterase inhibitor enhancing the endogenous activities of acetylcholine</p> Signup and view all the answers

    For what medical condition is physostigmine used?

    <p>Glaucoma</p> Signup and view all the answers

    More Like This

    Use Quizgecko on...
    Browser
    Open
    Browser
    Browser