Podcast
Questions and Answers
What is formed when a phosphoric acid molecule (H3PO4) is linked with two hydroxyl groups (–OH) of two other molecules?
What is formed when a phosphoric acid molecule (H3PO4) is linked with two hydroxyl groups (–OH) of two other molecules?
- Four ester bonds
- Three ester bonds
- One ester bond
- Two ester bonds (correct)
What is the critical role played by phosphodiester linkages in nucleic acids?
What is the critical role played by phosphodiester linkages in nucleic acids?
- Stabilizing the double helix structure
- Providing a binding site for proteins
- Regulating gene expression
- Linking nucleotides together (correct)
What is the primary reason for the negative charge of phosphate groups in nucleotides at pH 7?
What is the primary reason for the negative charge of phosphate groups in nucleotides at pH 7?
- They are bound to metal ions
- They are involved in hydrogen bonding with the sugar molecule
- They are completely ionized due to their pKa near 0 (correct)
- They are neutralized by ionic interactions with proteins and polyamines
What is the characteristic of the backbones of both DNA and RNA?
What is the characteristic of the backbones of both DNA and RNA?
In a nucleic acid sequence, what is the correct direction of reading?
In a nucleic acid sequence, what is the correct direction of reading?
What is the term used to describe a short nucleic acid?
What is the term used to describe a short nucleic acid?
What is the result of each ester bond formation in the creation of phosphodiester linkages?
What is the result of each ester bond formation in the creation of phosphodiester linkages?
What is the difference between the C5 atom of thymine and uracil?
What is the difference between the C5 atom of thymine and uracil?
What is the molecular formula of phosphoric acid?
What is the molecular formula of phosphoric acid?
What is the type of bond formed between the phosphate group and the sugar of a nucleotide?
What is the type of bond formed between the phosphate group and the sugar of a nucleotide?
What is the negatively charged group in nucleotides that attracts proteins?
What is the negatively charged group in nucleotides that attracts proteins?
What is the primary difference between the backbone of DNA and RNA molecules?
What is the primary difference between the backbone of DNA and RNA molecules?
What is the significance of the 5′ and 3′ ends of a polynucleotide chain?
What is the significance of the 5′ and 3′ ends of a polynucleotide chain?
Why do nucleic acids in cells often associate with proteins?
Why do nucleic acids in cells often associate with proteins?
What symbol is used to represent the phosphate group in nucleic acid sequences?
What symbol is used to represent the phosphate group in nucleic acid sequences?
What type of ring structure does purine contain?
What type of ring structure does purine contain?
Which of the following nucleotides is found in DNA but not in RNA?
Which of the following nucleotides is found in DNA but not in RNA?
What is the type of pentose found in the backbone of RNA molecules?
What is the type of pentose found in the backbone of RNA molecules?
